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Items: 1 to 20 of 102

1.

Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.

Gill JF, Delezie J, Santos G, McGuirk S, Schnyder S, Frank S, Rausch M, St-Pierre J, Handschin C.

Aging Cell. 2019 Oct;18(5):e12993. doi: 10.1111/acel.12993. Epub 2019 Jul 10.

2.

Improved skeletal muscle Ca2+ regulation in vivo following contractions in mice overexpressing PGC-1α.

Eshima H, Miura S, Senoo N, Hatakeyama K, Poole DC, Kano Y.

Am J Physiol Regul Integr Comp Physiol. 2017 Jun 1;312(6):R1017-R1028. doi: 10.1152/ajpregu.00032.2017. Epub 2017 Apr 24.

3.

PGC-1α affects aging-related changes in muscle and motor function by modulating specific exercise-mediated changes in old mice.

Gill JF, Santos G, Schnyder S, Handschin C.

Aging Cell. 2018 Feb;17(1). doi: 10.1111/acel.12697. Epub 2017 Oct 25.

6.

Autophagy activation, not peroxisome proliferator-activated receptor γ coactivator 1α, may mediate exercise-induced improvements in glucose handling during diet-induced obesity.

Rosa-Caldwell ME, Brown JL, Lee DE, Blackwell TA, Turner KW, Brown LA, Perry RA, Haynie WS, Washington TA, Greene NP.

Exp Physiol. 2017 Sep 1;102(9):1194-1207. doi: 10.1113/EP086406. Epub 2017 Jul 22.

7.

Exercise induces TFEB expression and activity in skeletal muscle in a PGC-1α-dependent manner.

Erlich AT, Brownlee DM, Beyfuss K, Hood DA.

Am J Physiol Cell Physiol. 2018 Jan 1;314(1):C62-C72. doi: 10.1152/ajpcell.00162.2017. Epub 2017 Oct 18.

8.

Thyroid hormone activation by type 2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-γ coactivator-1α expression in skeletal muscle.

Bocco BM, Louzada RA, Silvestre DH, Santos MC, Anne-Palmer E, Rangel IF, Abdalla S, Ferreira AC, Ribeiro MO, Gereben B, Carvalho DP, Bianco AC, Werneck-de-Castro JP.

J Physiol. 2016 Sep 15;594(18):5255-69. doi: 10.1113/JP272440. Epub 2016 Aug 18.

9.

Exercise training attenuates aging-associated mitochondrial dysfunction in rat skeletal muscle: role of PGC-1α.

Kang C, Chung E, Diffee G, Ji LL.

Exp Gerontol. 2013 Nov;48(11):1343-50. doi: 10.1016/j.exger.2013.08.004. Epub 2013 Aug 30.

PMID:
23994518
10.

Remodeling of calcium handling in skeletal muscle through PGC-1α: impact on force, fatigability, and fiber type.

Summermatter S, Thurnheer R, Santos G, Mosca B, Baum O, Treves S, Hoppeler H, Zorzato F, Handschin C.

Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C88-99. doi: 10.1152/ajpcell.00190.2011. Epub 2011 Sep 14.

11.

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C.

J Biol Chem. 2010 Oct 22;285(43):32793-800. doi: 10.1074/jbc.M110.145995. Epub 2010 Aug 17.

12.

Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation.

Sczelecki S, Besse-Patin A, Abboud A, Kleiner S, Laznik-Bogoslavski D, Wrann CD, Ruas JL, Haibe-Kains B, Estall JL.

Am J Physiol Endocrinol Metab. 2014 Jan 15;306(2):E157-67. doi: 10.1152/ajpendo.00578.2013. Epub 2013 Nov 26.

13.

Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner.

Halling JF, Ringholm S, Olesen J, Prats C, Pilegaard H.

Exp Gerontol. 2017 Oct 1;96:1-6. doi: 10.1016/j.exger.2017.05.020. Epub 2017 May 31.

PMID:
28577890
14.

The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading.

Cannavino J, Brocca L, Sandri M, Grassi B, Bottinelli R, Pellegrino MA.

J Physiol. 2015 Apr 15;593(8):1981-95. doi: 10.1113/jphysiol.2014.286740. Epub 2015 Feb 4.

15.

PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle.

Pagel-Langenickel I, Bao J, Joseph JJ, Schwartz DR, Mantell BS, Xu X, Raghavachari N, Sack MN.

J Biol Chem. 2008 Aug 15;283(33):22464-72. doi: 10.1074/jbc.M800842200. Epub 2008 Jun 25.

16.

Role of PGC-1α signaling in skeletal muscle health and disease.

Kang C, Li Ji L.

Ann N Y Acad Sci. 2012 Oct;1271:110-7. doi: 10.1111/j.1749-6632.2012.06738.x. Review.

17.

Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α.

Ringholm S, Olesen J, Pedersen JT, Brandt CT, Halling JF, Hellsten Y, Prats C, Pilegaard H.

Exp Gerontol. 2013 Nov;48(11):1311-8. doi: 10.1016/j.exger.2013.08.012. Epub 2013 Aug 29.

PMID:
23994519
18.

An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation.

Miura S, Kawanaka K, Kai Y, Tamura M, Goto M, Shiuchi T, Minokoshi Y, Ezaki O.

Endocrinology. 2007 Jul;148(7):3441-8. Epub 2007 Apr 19.

PMID:
17446185
19.

Mitochondrial biogenesis and peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) deacetylation by physical activity: intact adipocytokine signaling is required.

Li L, Pan R, Li R, Niemann B, Aurich AC, Chen Y, Rohrbach S.

Diabetes. 2011 Jan;60(1):157-67. doi: 10.2337/db10-0331. Epub 2010 Oct 7.

20.

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.

Finley LW, Lee J, Souza A, Desquiret-Dumas V, Bullock K, Rowe GC, Procaccio V, Clish CB, Arany Z, Haigis MC.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2931-6. doi: 10.1073/pnas.1115813109. Epub 2012 Feb 3.

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