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Items: 1 to 20 of 99

1.

LIR Motif-Containing Hyperdisulfide β-Ginkgotide is Cytoprotective, Adaptogenic, and Scaffold-Ready.

Dutta B, Huang J, To J, Tam JP.

Molecules. 2019 Jun 30;24(13). pii: E2417. doi: 10.3390/molecules24132417.

2.

β-Ginkgotides: Hyperdisulfide-constrained peptides from Ginkgo biloba.

Wong KH, Tan WL, Xiao T, Tam JP.

Sci Rep. 2017 Jul 21;7(1):6140. doi: 10.1038/s41598-017-06598-x.

3.

Ginkgotides: Proline-Rich Hevein-Like Peptides from Gymnosperm Ginkgo biloba.

Wong KH, Tan WL, Serra A, Xiao T, Sze SK, Yang D, Tam JP.

Front Plant Sci. 2016 Nov 3;7:1639. eCollection 2016.

4.

FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy.

Olsvik HL, Lamark T, Takagi K, Larsen KB, Evjen G, Øvervatn A, Mizushima T, Johansen T.

J Biol Chem. 2015 Dec 4;290(49):29361-74. doi: 10.1074/jbc.M115.686915. Epub 2015 Oct 14.

5.

A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ.

Kwon DH, Kim L, Kim BW, Kim JH, Roh KH, Choi EJ, Song HK.

Biochem Biophys Res Commun. 2017 Aug 26;490(3):1093-1099. doi: 10.1016/j.bbrc.2017.06.173. Epub 2017 Jun 29.

PMID:
28668392
6.

Cysteine-Rich Peptide Family with Unusual Disulfide Connectivity from Jasminum sambac.

Kumari G, Serra A, Shin J, Nguyen PQ, Sze SK, Yoon HS, Tam JP.

J Nat Prod. 2015 Nov 25;78(11):2791-9. doi: 10.1021/acs.jnatprod.5b00762. Epub 2015 Nov 10.

PMID:
26555361
7.

Development of LC3/GABARAP sensors containing a LIR and a hydrophobic domain to monitor autophagy.

Lee YK, Jun YW, Choi HE, Huh YH, Kaang BK, Jang DJ, Lee JA.

EMBO J. 2017 Apr 13;36(8):1100-1116. doi: 10.15252/embj.201696315. Epub 2017 Mar 20.

8.

iLIR database: A web resource for LIR motif-containing proteins in eukaryotes.

Jacomin AC, Samavedam S, Promponas V, Nezis IP.

Autophagy. 2016 Oct 2;12(10):1945-1953. Epub 2016 Aug 2.

9.

Development of GABARAP family protein-sensitive LIR-based probes for neuronal autophagy.

Jeon P, Park JH, Jun YW, Lee YK, Jang DJ, Lee JA.

Mol Brain. 2019 Apr 8;12(1):33. doi: 10.1186/s13041-019-0458-z.

10.

Acetylcholine mediates AMPK-dependent autophagic cytoprotection in H9c2 cells during hypoxia/reoxygenation injury.

Zhao M, Sun L, Yu XJ, Miao Y, Liu JJ, Wang H, Ren J, Zang WJ.

Cell Physiol Biochem. 2013;32(3):601-13. doi: 10.1159/000354464. Epub 2013 Sep 6.

11.

PEBP1, a RAF kinase inhibitory protein, negatively regulates starvation-induced autophagy by direct interaction with LC3.

Noh HS, Hah YS, Zada S, Ha JH, Sim G, Hwang JS, Lai TH, Nguyen HQ, Park JY, Kim HJ, Byun JH, Hahm JR, Kang KR, Kim DR.

Autophagy. 2016 Nov;12(11):2183-2196. Epub 2016 Aug 19.

12.

Methods for Studying Interactions Between Atg8/LC3/GABARAP and LIR-Containing Proteins.

Johansen T, Birgisdottir ÅB, Huber J, Kniss A, Dötsch V, Kirkin V, Rogov VV.

Methods Enzymol. 2017;587:143-169. doi: 10.1016/bs.mie.2016.10.023. Epub 2017 Jan 12.

PMID:
28253953
13.

Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1.

Rozenknop A, Rogov VV, Rogova NY, Löhr F, Güntert P, Dikic I, Dötsch V.

J Mol Biol. 2011 Jul 15;410(3):477-87. doi: 10.1016/j.jmb.2011.05.003. Epub 2011 May 18.

PMID:
21620860
14.

Structural basis of FYCO1 and MAP1LC3A interaction reveals a novel binding mode for Atg8-family proteins.

Cheng X, Wang Y, Gong Y, Li F, Guo Y, Hu S, Liu J, Pan L.

Autophagy. 2016 Aug 2;12(8):1330-9. doi: 10.1080/15548627.2016.1185590. Epub 2016 May 31.

15.

Characteristics and antifungal activity of a chitin binding protein from Ginkgo biloba.

Huang X, Xie W, Gong Z.

FEBS Lett. 2000 Jul 28;478(1-2):123-6.

16.

ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T.

J Biol Chem. 2012 Nov 16;287(47):39275-90. doi: 10.1074/jbc.M112.378109. Epub 2012 Oct 5.

17.

Time-resolved FRET and NMR analyses reveal selective binding of peptides containing the LC3-interacting region to ATG8 family proteins.

Atkinson JM, Ye Y, Gebru MT, Liu Q, Zhou S, Young MM, Takahashi Y, Lin Q, Tian F, Wang HG.

J Biol Chem. 2019 Sep 20;294(38):14033-14042. doi: 10.1074/jbc.RA119.008723. Epub 2019 Jul 30.

PMID:
31362979
18.

Ginkgo biloba exocarp extracts induces autophagy in Lewis lung cancer cells involving AMPK / mTOR / p70S6k signaling pathway.

Cao C, Han D, Su Y, Ge Y, Chen H, Xu A.

Biomed Pharmacother. 2017 Sep;93:1128-1135. doi: 10.1016/j.biopha.2017.07.036. Epub 2017 Jul 19.

PMID:
28738521
19.

Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold.

Tan WL, Wong KH, Lei J, Sakai N, Tan HW, Hilgenfeld R, Tam JP.

Sci Rep. 2017 Jul 12;7(1):5194. doi: 10.1038/s41598-017-05037-1.

20.

Beyond Atg8 binding: The role of AIM/LIR motifs in autophagy.

Fracchiolla D, Sawa-Makarska J, Martens S.

Autophagy. 2017 May 4;13(5):978-979. doi: 10.1080/15548627.2016.1277311. Epub 2017 Jan 25. Review.

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