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Items: 1 to 20 of 101

1.

Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking.

Linscheid N, Logantha SJRJ, Poulsen PC, Zhang S, Schrölkamp M, Egerod KL, Thompson JJ, Kitmitto A, Galli G, Humphries MJ, Zhang H, Pers TH, Olsen JV, Boyett M, Lundby A.

Nat Commun. 2019 Jun 28;10(1):2889. doi: 10.1038/s41467-019-10709-9.

2.

Contribution of small conductance K+ channels to sinoatrial node pacemaker activity: insights from atrial-specific Na+ /Ca2+ exchange knockout mice.

Torrente AG, Zhang R, Wang H, Zaini A, Kim B, Yue X, Philipson KD, Goldhaber JI.

J Physiol. 2017 Jun 15;595(12):3847-3865. doi: 10.1113/JP274249. Epub 2017 May 13.

3.

Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking.

Lei M, Jones SA, Liu J, Lancaster MK, Fung SS, Dobrzynski H, Camelliti P, Maier SK, Noble D, Boyett MR.

J Physiol. 2004 Sep 15;559(Pt 3):835-48. Epub 2004 Jul 14.

4.

Regulation of calcium clock-mediated pacemaking by inositol-1,4,5-trisphosphate receptors in mouse sinoatrial nodal cells.

Kapoor N, Tran A, Kang J, Zhang R, Philipson KD, Goldhaber JI.

J Physiol. 2015 Jun 15;593(12):2649-63. doi: 10.1113/JP270082. Epub 2015 May 26.

5.

Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix.

Gluck JM, Herren AW, Yechikov S, Kao HKJ, Khan A, Phinney BS, Chiamvimonvat N, Chan JW, Lieu DK.

PLoS One. 2017 Sep 21;12(9):e0185125. doi: 10.1371/journal.pone.0185125. eCollection 2017.

6.

Atrio-sinus interaction demonstrated by blockade of the rapid delayed rectifier current.

Verheijck EE, Wilders R, Bouman LN.

Circulation. 2002 Feb 19;105(7):880-5.

PMID:
11854131
7.

Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome.

Butters TD, Aslanidi OV, Inada S, Boyett MR, Hancox JC, Lei M, Zhang H.

Circ Res. 2010 Jul 9;107(1):126-37. doi: 10.1161/CIRCRESAHA.110.219949. Epub 2010 May 6.

8.

Current concepts of anatomy and electrophysiology of the sinus node.

Murphy C, Lazzara R.

J Interv Card Electrophysiol. 2016 Jun;46(1):9-18. doi: 10.1007/s10840-016-0137-2. Epub 2016 May 3. Review.

PMID:
27142063
9.

Roles of sarcoplasmic reticulum Ca2+ cycling and Na+/Ca2+ exchanger in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models.

Kurata Y, Hisatome I, Shibamoto T.

Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2285-300. doi: 10.1152/ajpheart.00221.2011. Epub 2012 Mar 23.

10.

Electrophysiological heterogeneity of pacemaker cells in the rabbit intercaval region, including the SA node: insights from recording multiple ion currents in each cell.

Monfredi O, Tsutsui K, Ziman B, Stern MD, Lakatta EG, Maltsev VA.

Am J Physiol Heart Circ Physiol. 2018 Mar 1;314(3):H403-H414. doi: 10.1152/ajpheart.00253.2016. Epub 2017 Sep 15.

11.

Regional difference in dynamical property of sinoatrial node pacemaking: role of na+ channel current.

Kurata Y, Matsuda H, Hisatome I, Shibamoto T.

Biophys J. 2008 Jul;95(2):951-77. doi: 10.1529/biophysj.107.112854. Epub 2008 Apr 4.

12.

Single cells isolated from human sinoatrial node: action potentials and numerical reconstruction of pacemaker current.

Verkerk AO, van Borren MM, Peters RJ, Broekhuis E, Lam KY, Coronel R, de Bakker JM, Tan HL, Wilders R.

Conf Proc IEEE Eng Med Biol Soc. 2007;2007:904-7.

PMID:
18002103
13.

A coupled SYSTEM of intracellular Ca2+ clocks and surface membrane voltage clocks controls the timekeeping mechanism of the heart's pacemaker.

Lakatta EG, Maltsev VA, Vinogradova TM.

Circ Res. 2010 Mar 5;106(4):659-73. doi: 10.1161/CIRCRESAHA.109.206078. Review.

14.

Pacemaker activity and ionic currents in mouse atrioventricular node cells.

Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME.

Channels (Austin). 2011 May-Jun;5(3):241-50. Epub 2011 May 1.

15.

The role of the calcium and the voltage clocks in sinoatrial node dysfunction.

Joung B, Chen PS, Lin SF.

Yonsei Med J. 2011 Mar;52(2):211-9. doi: 10.3349/ymj.2011.52.2.211. Review.

16.

Desmosomal junctions are necessary for adult sinus node function.

Mezzano V, Liang Y, Wright AT, Lyon RC, Pfeiffer E, Song MY, Gu Y, Dalton ND, Scheinman M, Peterson KL, Evans SM, Fowler S, Cerrone M, McCulloch AD, Sheikh F.

Cardiovasc Res. 2016 Aug 1;111(3):274-86. doi: 10.1093/cvr/cvw083. Epub 2016 Apr 20.

17.

Role of pacemaking current in cardiac nodes: insights from a comparative study of sinoatrial node and atrioventricular node.

Liu J, Noble PJ, Xiao G, Abdelrahman M, Dobrzynski H, Boyett MR, Lei M, Noble D.

Prog Biophys Mol Biol. 2008 Jan-Apr;96(1-3):294-304. Epub 2007 Aug 10. Review.

PMID:
17905415
18.

Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice.

Glukhov AV, Fedorov VV, Anderson ME, Mohler PJ, Efimov IR.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H482-91. doi: 10.1152/ajpheart.00756.2009. Epub 2010 Jun 4.

19.

Computational evaluation of the roles of Na+ current, iNa, and cell death in cardiac pacemaking and driving.

Zhang H, Zhao Y, Lei M, Dobrzynski H, Liu JH, Holden AV, Boyett MR.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H165-74. Epub 2006 Jul 28.

20.

Carvedilol analog modulates both basal and stimulated sinoatrial node automaticity.

Shinohara T, Kim D, Joung B, Maruyama M, Vembaiyan K, Back TG, Wayne Chen SR, Chen PS, Lin SF.

Heart Vessels. 2014 May;29(3):396-403. doi: 10.1007/s00380-013-0378-2. Epub 2013 Jul 9.

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