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Items: 1 to 20 of 93

1.

The Human TET2 Gene Contains Three Distinct Promoter Regions With Differing Tissue and Developmental Specificities.

Lou H, Li H, Ho KJ, Cai LL, Huang AS, Shank TR, Verneris MR, Nickerson ML, Dean M, Anderson SK.

Front Cell Dev Biol. 2019 Jun 7;7:99. doi: 10.3389/fcell.2019.00099. eCollection 2019.

2.

Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation.

Sohni A, Bartoccetti M, Khoueiry R, Spans L, Vande Velde J, De Troyer L, Pulakanti K, Claessens F, Rao S, Koh KP.

Mol Cell Biol. 2015 Mar;35(6):1026-42. doi: 10.1128/MCB.01172-14. Epub 2015 Jan 12.

3.

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.

Ruiz MA, Rivers A, Ibanez V, Vaitkus K, Mahmud N, DeSimone J, Lavelle D.

Epigenetics. 2015;10(5):397-407. doi: 10.1080/15592294.2015.1039220.

4.

TET2 Inhibits Differentiation of Embryonic Stem Cells but Does Not Overcome Methylation-Induced Gene Silencing.

Norman L, Tarrant P, Chevassut T.

Bone Marrow Res. 2014;2014:986571. doi: 10.1155/2014/986571. Epub 2014 Aug 25.

5.

TET family proteins and 5-hydroxymethylcytosine in esophageal squamous cell carcinoma.

Murata A, Baba Y, Ishimoto T, Miyake K, Kosumi K, Harada K, Kurashige J, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Yamamoto M, Oda S, Watanabe M, Nakao M, Baba H.

Oncotarget. 2015 Sep 15;6(27):23372-82.

6.

TET enzymes are successively expressed during human spermatogenesis and their expression level is pivotal for male fertility.

Ni K, Dansranjavin T, Rogenhofer N, Oeztuerk N, Deuker J, Bergmann M, Schuppe HC, Wagenlehner F, Weidner W, Steger K, Schagdarsurengin U.

Hum Reprod. 2016 Jul;31(7):1411-24. doi: 10.1093/humrep/dew096. Epub 2016 May 1.

PMID:
27141042
7.

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.

Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen SE, Peters B, Rao A.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1361-6. doi: 10.1073/pnas.1322921111. Epub 2014 Jan 13.

8.

Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation.

Shen Q, Zhang Q, Shi Y, Shi Q, Jiang Y, Gu Y, Li Z, Li X, Zhao K, Wang C, Li N, Cao X.

Nature. 2018 Feb 1;554(7690):123-127. doi: 10.1038/nature25434. Epub 2018 Jan 24.

PMID:
29364877
9.

A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.

Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, Joung JK, Rao A, Look AT.

Mol Cell Biol. 2015 Mar;35(5):789-804. doi: 10.1128/MCB.00971-14. Epub 2014 Dec 15.

10.

TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.

Mahfoudhi E, Talhaoui I, Cabagnols X, Della Valle V, Secardin L, Rameau P, Bernard OA, Ishchenko AA, Abbes S, Vainchenker W, Saparbaev M, Plo I.

DNA Repair (Amst). 2016 Jul;43:78-88. doi: 10.1016/j.dnarep.2016.05.031. Epub 2016 May 24.

PMID:
27289557
11.

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

Ko M, An J, Bandukwala HS, Chavez L, Aijö T, Pastor WA, Segal MF, Li H, Koh KP, Lähdesmäki H, Hogan PG, Aravind L, Rao A.

Nature. 2013 May 2;497(7447):122-6. doi: 10.1038/nature12052. Epub 2013 Apr 7.

12.

Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro.

Zhong X, Wang QQ, Li JW, Zhang YM, An XR, Hou J.

Sci Rep. 2017 Mar 8;7:43539. doi: 10.1038/srep43539.

13.
14.

Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency.

Wille CK, Li Y, Rui L, Johannsen EC, Kenney SC.

J Virol. 2017 Feb 14;91(5). pii: e01987-16. doi: 10.1128/JVI.01987-16. Print 2017 Mar 1.

15.

Tet2 restrains inflammatory gene expression in macrophages.

Cull AH, Snetsinger B, Buckstein R, Wells RA, Rauh MJ.

Exp Hematol. 2017 Nov;55:56-70.e13. doi: 10.1016/j.exphem.2017.08.001. Epub 2017 Aug 18.

16.

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases.

Solary E, Bernard OA, Tefferi A, Fuks F, Vainchenker W.

Leukemia. 2014 Mar;28(3):485-96. doi: 10.1038/leu.2013.337. Epub 2013 Nov 13. Review.

PMID:
24220273
17.

The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells.

Ichiyama K, Chen T, Wang X, Yan X, Kim BS, Tanaka S, Ndiaye-Lobry D, Deng Y, Zou Y, Zheng P, Tian Q, Aifantis I, Wei L, Dong C.

Immunity. 2015 Apr 21;42(4):613-26. doi: 10.1016/j.immuni.2015.03.005. Epub 2015 Apr 7. Erratum in: Immunity. 2015 Jun 16;42(6):1214.

18.

Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.

Rakoczy J, Padmanabhan N, Krzak AM, Kieckbusch J, Cindrova-Davies T, Watson ED.

Placenta. 2017 Nov;59:46-56. doi: 10.1016/j.placenta.2017.09.008. Epub 2017 Sep 22.

PMID:
29108636
19.

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

Minor EA, Court BL, Young JI, Wang G.

J Biol Chem. 2013 May 10;288(19):13669-74. doi: 10.1074/jbc.C113.464800. Epub 2013 Apr 2.

20.

Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.

Putiri EL, Tiedemann RL, Thompson JJ, Liu C, Ho T, Choi JH, Robertson KD.

Genome Biol. 2014 Jun 23;15(6):R81. doi: 10.1186/gb-2014-15-6-r81.

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