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Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury.

Ye Z, Zhang L, Li R, Dong W, Liu S, Li Z, Liang H, Wang L, Shi W, Malik AB, Cheng KT, Liang X.

Kidney Blood Press Res. 2019 Jun 21:1-14. doi: 10.1159/000499685. [Epub ahead of print]


Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury.

Zhang Z, Shao X, Jiang N, Mou S, Gu L, Li S, Lin Q, He Y, Zhang M, Zhou W, Ni Z.

Cell Death Dis. 2018 Sep 24;9(10):983. doi: 10.1038/s41419-018-1023-x.


Knockout of interleukin-17A protects against sepsis-associated acute kidney injury.

Luo CJ, Luo F, Zhang L, Xu Y, Cai GY, Fu B, Feng Z, Sun XF, Chen XM.

Ann Intensive Care. 2016 Dec;6(1):56. doi: 10.1186/s13613-016-0157-1. Epub 2016 Jun 22.


Inhibition of hepatic cells pyroptosis attenuates CLP-induced acute liver injury.

Chen YL, Xu G, Liang X, Wei J, Luo J, Chen GN, Yan XD, Wen XP, Zhong M, Lv X.

Am J Transl Res. 2016 Dec 15;8(12):5685-5695. eCollection 2016.


Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice.

Wu DD, Pan PH, Liu B, Su XL, Zhang LM, Tan HY, Cao Z, Zhou ZR, Li HT, Li HS, Huang L, Li YY.

Chin Med J (Engl). 2015 Oct 5;128(19):2638-45. doi: 10.4103/0366-6999.166039.


miR-21 promotes NLRP3 inflammasome activation to mediate pyroptosis and endotoxic shock.

Xue Z, Xi Q, Liu H, Guo X, Zhang J, Zhang Z, Li Y, Yang G, Zhou D, Yang H, Zhang L, Zhang Q, Gu C, Yang J, Da Y, Yao Z, Duo S, Zhang R.

Cell Death Dis. 2019 Jun 12;10(6):461. doi: 10.1038/s41419-019-1713-z.


MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis.

Wu H, Huang T, Ying L, Han C, Li D, Xu Y, Zhang M, Mou S, Dong Z.

Cell Physiol Biochem. 2016;40(6):1692-1705. doi: 10.1159/000453218. Epub 2016 Dec 23.


Propofol Does Not Reduce Pyroptosis of Enterocytes and Intestinal Epithelial Injury After Lipopolysaccharide Challenge.

Zhang XY, Chen X, Zhang HF, Guan S, Wen SH, Huang WQ, Liu ZM.

Dig Dis Sci. 2018 Jan;63(1):81-91. doi: 10.1007/s10620-017-4801-x. Epub 2017 Oct 23.


Ischemia-reperfusion induces renal tubule pyroptosis via the CHOP-caspase-11 pathway.

Yang JR, Yao FH, Zhang JG, Ji ZY, Li KL, Zhan J, Tong YN, Lin LR, He YN.

Am J Physiol Renal Physiol. 2014 Jan 1;306(1):F75-84. doi: 10.1152/ajprenal.00117.2013. Epub 2013 Oct 16.


[NLRP3 inflammasome induces pyroptosis in lung tissues of radiation-induced lung injury in mice].

Han R, Wu D, Deng S, Liu T, Zhang T, Xu Y.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Sep;33(9):1206-1211. Chinese.


Bradykinin B2 receptors play a neuroprotective role in Hypoxia/reoxygenation injury related to pyroptosis pathway.

Tang M, Li X, Liu P, Wang J, He F, Zhu X.

Curr Neurovasc Res. 2018;15(2):138-144. doi: 10.2174/1567202615666180528073141.


Total Coumarins from Hydrangea paniculata Show Renal Protective Effects in Lipopolysaccharide-Induced Acute Kidney Injury via Anti-inflammatory and Antioxidant Activities.

Zhang S, Ma J, Sheng L, Zhang D, Chen X, Yang J, Wang D.

Front Pharmacol. 2017 Dec 14;8:872. doi: 10.3389/fphar.2017.00872. eCollection 2017.


Vitamin D receptor activation protects against lipopolysaccharide-induced acute kidney injury through suppression of tubular cell apoptosis.

Du J, Jiang S, Hu Z, Tang S, Sun Y, He J, Li Z, Yi B, Wang J, Zhang H, Li YC.

Am J Physiol Renal Physiol. 2019 May 1;316(5):F1068-F1077. doi: 10.1152/ajprenal.00332.2018. Epub 2019 Mar 13.


[Expression and significance of c-FLIP protein in sepsis mice with acute kidney injury].

Fan H, Le J, Chen G, Sun M, Ye J, Zhu Y, Zhu J.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Dec;30(12):1132-1136. doi: 10.3760/cma.j.issn.2095-4352.2018.12.006. Chinese.


Inflammatory cytokines and lipopolysaccharide induce Fas-mediated apoptosis in renal tubular cells.

Jo SK, Cha DR, Cho WY, Kim HK, Chang KH, Yun SY, Won NH.

Nephron. 2002 Jul;91(3):406-15.


CYLD deficiency exacerbates lipopolysaccharide (LPS)-induced pyroptosis in astrocytes of mice with sepsis.

Li L, Shu MQ, Chen J.

Biochem Biophys Res Commun. 2019 Jul 5;514(4):1066-1073. doi: 10.1016/j.bbrc.2019.05.033. Epub 2019 May 13.


The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.

Deng M, Tang Y, Li W, Wang X, Zhang R, Zhang X, Zhao X, Liu J, Tang C, Liu Z, Huang Y, Peng H, Xiao L, Tang D, Scott MJ, Wang Q, Liu J, Xiao X, Watkins S, Li J, Yang H, Wang H, Chen F, Tracey KJ, Billiar TR, Lu B.

Immunity. 2018 Oct 16;49(4):740-753.e7. doi: 10.1016/j.immuni.2018.08.016. Epub 2018 Oct 9.


Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury.

Cheng KT, Xiong S, Ye Z, Hong Z, Di A, Tsang KM, Gao X, An S, Mittal M, Vogel SM, Miao EA, Rehman J, Malik AB.

J Clin Invest. 2017 Nov 1;127(11):4124-4135. doi: 10.1172/JCI94495. Epub 2017 Oct 9.


RIPK3 mediates renal tubular epithelial cell apoptosis in endotoxin‑induced acute kidney injury.

Zhang S, Li R, Dong W, Yang H, Zhang L, Chen Y, Wang W, Li C, Wu Y, Ye Z, Zhao X, Li Z, Zhang M, Liu S, Liang X.

Mol Med Rep. 2019 Aug;20(2):1613-1620. doi: 10.3892/mmr.2019.10416. Epub 2019 Jun 24.


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