Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 100

1.

A novel mPGES-1 inhibitor alleviates inflammatory responses by downregulating PGE2 in experimental models.

Lee HH, Moon Y, Shin JS, Lee JH, Kim TW, Jang C, Park C, Lee J, Kim Y, Kim Y, Werz O, Park BY, Lee JY, Lee KT.

Prostaglandins Other Lipid Mediat. 2019 Jun 20;144:106347. doi: 10.1016/j.prostaglandins.2019.106347. [Epub ahead of print]

PMID:
31229523
2.

RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNFalpha or anti-IL-1 therapies.

Stolina M, Schett G, Dwyer D, Vonderfecht S, Middleton S, Duryea D, Pacheco E, Van G, Bolon B, Feige U, Zack D, Kostenuik P.

Arthritis Res Ther. 2009;11(6):R187. doi: 10.1186/ar2879. Epub 2009 Dec 11.

3.

Inhibition of microsomal prostaglandin E-synthase-1 (mPGES-1) selectively suppresses PGE2 in an in vitro equine inflammation model.

Martin EM, Jones SL.

Vet Immunol Immunopathol. 2017 Oct;192:33-40. doi: 10.1016/j.vetimm.2017.09.008. Epub 2017 Oct 3.

4.
5.

Aminothiazoles inhibit RANKL- and LPS-mediated osteoclastogenesis and PGE2 production in RAW 264.7 cells.

Kats A, Norgård M, Wondimu Z, Koro C, Concha Quezada H, Andersson G, Yucel-Lindberg T.

J Cell Mol Med. 2016 Jun;20(6):1128-38. doi: 10.1111/jcmm.12814. Epub 2016 Mar 14.

6.
7.

Anti-inflammatory effects of 7-hydroxyl-1-methylindole-3-acetonitrile, a synthetic arvelexin derivative, on the macrophages through destabilizing mPGES-1 mRNA and suppressing NF-κB activation.

Shin JS, Choi HE, Kim SD, Lee YS, Cho YW, Lee KT.

Chem Biol Interact. 2014 Dec 5;224:68-77. doi: 10.1016/j.cbi.2014.10.004. Epub 2014 Oct 19.

PMID:
25451575
8.

Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.

Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ.

Prostaglandins Leukot Essent Fatty Acids. 2013 Oct;89(5):351-8. doi: 10.1016/j.plefa.2013.08.003. Epub 2013 Aug 30.

9.

Aminothiazoles inhibit osteoclastogenesis and PGE2 production in LPS-stimulated co-cultures of periodontal ligament and RAW 264.7 cells, and RANKL-mediated osteoclastogenesis and bone resorption in PBMCs.

Kats A, Gerasimcik N, Näreoja T, Nederberg J, Grenlöv S, Lagnöhed E, Desai S, Andersson G, Yucel-Lindberg T.

J Cell Mol Med. 2019 Feb;23(2):1152-1163. doi: 10.1111/jcmm.14015. Epub 2018 Dec 1.

10.

Expression of mPGES-1 and IP mRNA is reduced by LLLT in both subplantar and brain tissues in the model of peripheral inflammation induced by carrageenan.

Chagas LR, Silva JA Jr, de Almeida Pires J, Costa MS.

Lasers Med Sci. 2015 Jan;30(1):83-8. doi: 10.1007/s10103-014-1622-4. Epub 2014 Jun 29.

PMID:
24974175
11.
12.

Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile.

Boulet L, Ouellet M, Bateman KP, Ethier D, Percival MD, Riendeau D, Mancini JA, Méthot N.

J Biol Chem. 2004 May 28;279(22):23229-37. Epub 2004 Mar 11.

13.

Characterization of a new mPGES-1 inhibitor in rat models of inflammation.

Leclerc P, Pawelzik SC, Idborg H, Spahiu L, Larsson C, Stenberg P, Korotkova M, Jakobsson PJ.

Prostaglandins Other Lipid Mediat. 2013 Apr-May;102-103:1-12. doi: 10.1016/j.prostaglandins.2013.03.005. Epub 2013 Mar 23.

PMID:
23528231
14.

Protective effects of total flavonoids of Astragalus against adjuvant-induced arthritis in rats by regulating OPG/RANKL/NF-κB pathway.

Liu XY, Xu L, Wang Y, Li JX, Zhang Y, Zhang C, Wang SS, Zhang XM.

Int Immunopharmacol. 2017 Mar;44:105-114. doi: 10.1016/j.intimp.2017.01.010. Epub 2017 Jan 13.

PMID:
28092862
15.

Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo.

Park SM, Min BG, Jung JY, Jegal KH, Lee CW, Kim KY, Kim YW, Choi YW, Cho IJ, Ku SK, Kim SC.

BMC Complement Altern Med. 2018 Jan 19;18(1):20. doi: 10.1186/s12906-018-2088-x.

16.

Lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 mediates late-phase PGE2 production in bone marrow derived macrophages.

Xiao L, Ornatowska M, Zhao G, Cao H, Yu R, Deng J, Li Y, Zhao Q, Sadikot RT, Christman JW.

PLoS One. 2012;7(11):e50244. doi: 10.1371/journal.pone.0050244. Epub 2012 Nov 30.

17.

Fatty acid-binding protein 5 controls microsomal prostaglandin E synthase 1 (mPGES-1) induction during inflammation.

Bogdan D, Falcone J, Kanjiya MP, Park SH, Carbonetti G, Studholme K, Gomez M, Lu Y, Elmes MW, Smietalo N, Yan S, Ojima I, Puopolo M, Kaczocha M.

J Biol Chem. 2018 Apr 6;293(14):5295-5306. doi: 10.1074/jbc.RA118.001593. Epub 2018 Feb 13.

18.

Microglia-specific expression of microsomal prostaglandin E2 synthase-1 contributes to lipopolysaccharide-induced prostaglandin E2 production.

Ikeda-Matsuo Y, Ikegaya Y, Matsuki N, Uematsu S, Akira S, Sasaki Y.

J Neurochem. 2005 Sep;94(6):1546-58. Epub 2005 Jul 5.

19.

Biomolecular evidence of anti-inflammatory effects by Clematis mandshurica Ruprecht root extract in rodent cells.

Lee CW, Park SM, Kim YS, Jegal KH, Lee JR, Cho IJ, Ku SK, Lee JY, Ahn YT, Son Y, Ju SA, Kim SC, An WG.

J Ethnopharmacol. 2014 Sep 11;155(2):1141-55. doi: 10.1016/j.jep.2014.06.048. Epub 2014 Jun 27.

PMID:
24975194
20.

Signal pathways involved in the regulation of prostaglandin E synthase-1 in human gingival fibroblasts.

Yucel-Lindberg T, Olsson T, Kawakami T.

Cell Signal. 2006 Dec;18(12):2131-42.

PMID:
16766159

Supplemental Content

Support Center