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Items: 1 to 20 of 102


Si-Miao-Yong-An decoction ameliorates cardiac function through restoring the equilibrium of SOD and NOX2 in heart failure mice.

Ren Y, Chen X, Li P, Zhang H, Su C, Zeng Z, Wu Y, Xie X, Wang Q, Han J, Guo S, Liu B, Wang W.

Pharmacol Res. 2019 Jun 20;146:104318. doi: 10.1016/j.phrs.2019.104318. [Epub ahead of print]


Dissection of mechanisms of Chinese medicinal formula Si-Miao-Yong-an decoction protects against cardiac hypertrophy and fibrosis in isoprenaline-induced heart failure.

Zhao Y, Jiang Y, Chen Y, Zhang F, Zhang X, Zhu L, Yao X.

J Ethnopharmacol. 2019 Jun 29:112050. doi: 10.1016/j.jep.2019.112050. [Epub ahead of print]


Effects of Xin-Ji-Er-Kang on heart failure induced by myocardial infarction: Role of inflammation, oxidative stress and endothelial dysfunction.

Hu J, Cheng P, Huang GY, Cai GW, Lian FZ, Wang XY, Gao S.

Phytomedicine. 2018 Mar 15;42:245-257. doi: 10.1016/j.phymed.2018.03.036. Epub 2018 Mar 19.


Overexpression of miR-142-3p improves mitochondrial function in cardiac hypertrophy.

Liu BL, Cheng M, Hu S, Wang S, Wang L, Tu X, Huang CX, Jiang H, Wu G.

Biomed Pharmacother. 2018 Dec;108:1347-1356. doi: 10.1016/j.biopha.2018.09.146. Epub 2018 Oct 4.


Loss of NOX2 (gp91phox) prevents oxidative stress and progression to advanced heart failure.

Parajuli N, Patel VB, Wang W, Basu R, Oudit GY.

Clin Sci (Lond). 2014 Sep;127(5):331-40. doi: 10.1042/CS20130787.


Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model.

Peng L, Li M, Xu YZ, Zhang GY, Yang C, Zhou YN, Li LJ, Zhang JP.

J Ethnopharmacol. 2012 Aug 30;143(1):241-8. doi: 10.1016/j.jep.2012.06.030. Epub 2012 Jun 28.


YiQiFuMai Powder Injection attenuates coronary artery ligation-induced myocardial remodeling and heart failure through modulating MAPKs signaling pathway.

Pang LZ, Ju AC, Zheng XJ, Li F, Song YF, Zhao Y, Gu YF, Chen FL, Liu CH, Qi J, Gao Z, Kou JP, Yu BY.

J Ethnopharmacol. 2017 Apr 18;202:67-77. doi: 10.1016/j.jep.2017.02.032. Epub 2017 Feb 22.


1H NMR-based dynamic metabolomics delineates the therapeutic effects of Baoyuan decoction on isoproterenol-induced cardiac hypertrophy.

Du Z, Wen R, Liu Q, Wang J, Lu Y, Zhao M, Guo X, Tu P, Jiang Y.

J Pharm Biomed Anal. 2019 Jan 30;163:64-77. doi: 10.1016/j.jpba.2018.09.049. Epub 2018 Sep 29.


Hydrogen (H2) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways.

Zhang Y, Xu J, Long Z, Wang C, Wang L, Sun P, Li P, Wang T.

Front Pharmacol. 2016 Oct 27;7:392. eCollection 2016.


Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation.

Ahn B, Coblentz PD, Beharry AW, Patel N, Judge AR, Moylan JS, Hoopes CW, Bonnell MR, Ferreira LF.

Front Physiol. 2017 Jan 9;7:686. doi: 10.3389/fphys.2016.00686. eCollection 2016.


Oltipraz attenuates the progression of heart failure in rats through inhibiting oxidative stress and inflammatory response.

Tang Y, Guo M, Ma XY, Sun WP, Hao MH, Zhu HY.

Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8918-8923. doi: 10.26355/eurrev_201812_16661.


Depressed Corin Levels Indicate Early Systolic Dysfunction Before Increases of Atrial Natriuretic Peptide/B-Type Natriuretic Peptide and Heart Failure Development.

Tripathi R, Wang D, Sullivan R, Fan TH, Gladysheva IP, Reed GL.

Hypertension. 2016 Feb;67(2):362-7. doi: 10.1161/HYPERTENSIONAHA.115.06300. Epub 2015 Dec 14.


Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.

Bodiga S, Zhong JC, Wang W, Basu R, Lo J, Liu GC, Guo D, Holland SM, Scholey JW, Penninger JM, Kassiri Z, Oudit GY.

Cardiovasc Res. 2011 Jul 1;91(1):151-61. doi: 10.1093/cvr/cvr036. Epub 2011 Feb 1.


Tanshinone IIA protects against cardiac hypertrophy via inhibiting calcineurin/NFATc3 pathway.

Tan X, Li J, Wang X, Chen N, Cai B, Wang G, Shan H, Dong D, Liu Y, Li X, Yang F, Li X, Zhang P, Li X, Yang B, Lu Y.

Int J Biol Sci. 2011 Apr 7;7(3):383-9.


Chronic cocaine-induced cardiac oxidative stress and mitogen-activated protein kinase activation: the role of Nox2 oxidase.

Fan L, Sawbridge D, George V, Teng L, Bailey A, Kitchen I, Li JM.

J Pharmacol Exp Ther. 2009 Jan;328(1):99-106. doi: 10.1124/jpet.108.145201. Epub 2008 Oct 24.


Loss of p47phox subunit enhances susceptibility to biomechanical stress and heart failure because of dysregulation of cortactin and actin filaments.

Patel VB, Wang Z, Fan D, Zhabyeyev P, Basu R, Das SK, Wang W, Desaulniers J, Holland SM, Kassiri Z, Oudit GY.

Circ Res. 2013 Jun 7;112(12):1542-56. doi: 10.1161/CIRCRESAHA.111.300299. Epub 2013 Apr 3.


A metabolite of Danshen formulae attenuates cardiac fibrosis induced by isoprenaline, via a NOX2/ROS/p38 pathway.

Yin Q, Lu H, Bai Y, Tian A, Yang Q, Wu J, Yang C, Fan TP, Zhang Y, Zheng X, Zheng X, Li Z.

Br J Pharmacol. 2015 Dec;172(23):5573-85. doi: 10.1111/bph.13133. Epub 2015 May 5.


Delivery of Nox2-NADPH oxidase siRNA with polyketal nanoparticles for improving cardiac function following myocardial infarction.

Somasuntharam I, Boopathy AV, Khan RS, Martinez MD, Brown ME, Murthy N, Davis ME.

Biomaterials. 2013 Oct;34(31):7790-8. doi: 10.1016/j.biomaterials.2013.06.051. Epub 2013 Jul 13.


Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production.

Matono R, Miyano K, Kiyohara T, Sumimoto H.

J Biol Chem. 2014 Sep 5;289(36):24874-84. doi: 10.1074/jbc.M114.581785. Epub 2014 Jul 23.

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