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Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells.

Pettinato G, Lehoux S, Ramanathan R, Salem MM, He LX, Muse O, Flaumenhaft R, Thompson MT, Rouse EA, Cummings RD, Wen X, Fisher RA.

Sci Rep. 2019 Jun 20;9(1):8920. doi: 10.1038/s41598-019-45514-3.


Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies.

Yu Y, Liu H, Ikeda Y, Amiot BP, Rinaldo P, Duncan SA, Nyberg SL.

Stem Cell Res. 2012 Nov;9(3):196-207. doi: 10.1016/j.scr.2012.06.004. Epub 2012 Jun 28.


Differentiation and transplantation of human induced pluripotent stem cell-derived hepatocyte-like cells.

Asgari S, Moslem M, Bagheri-Lankarani K, Pournasr B, Miryounesi M, Baharvand H.

Stem Cell Rev. 2013 Aug;9(4):493-504. doi: 10.1007/s12015-011-9330-y.


Generation of hepatocyte-like cells from human induced pluripotent stem (iPS) cells by co-culturing embryoid body cells with liver non-parenchymal cell line TWNT-1.

Javed MS, Yaqoob N, Iwamuro M, Kobayashi N, Fujiwara T.

J Coll Physicians Surg Pak. 2014 Feb;24(2):91-6. doi: 02.2014/JCPSP.9196.


Differentiation of human foreskin fibroblast-derived induced pluripotent stem cells into hepatocyte-like cells.

Wang J, Zhao P, Wan Z, Jin X, Cheng Y, Yan T, Qing S, Ding N, Xin S.

Cell Biochem Funct. 2016 Oct;34(7):475-482. doi: 10.1002/cbf.3210. Epub 2016 Aug 29.


Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/β-catenin Pathway Inhibition.

Pettinato G, Ramanathan R, Fisher RA, Mangino MJ, Zhang N, Wen X.

Sci Rep. 2016 Sep 12;6:32888. doi: 10.1038/srep32888.


Efficient Differentiation of Human Induced Pluripotent Stem Cell (hiPSC) Derived Hepatocyte-Like Cells on hMSCs Feeder.

Mobarra N, Soleimani M, Kouhkan F, Hesari Z, Lahmy R, Mossahebi-Mohammadi M, Arefian E, Jaafarpour Z, Nasiri H, Pakzad R, Tavakoli R, Pasalar P.

Int J Hematol Oncol Stem Cell Res. 2014 Oct 1;8(4):20-9.


Three-dimensional hydrogel culture conditions promote the differentiation of human induced pluripotent stem cells into hepatocytes.

Luo Y, Lou C, Zhang S, Zhu Z, Xing Q, Wang P, Liu T, Liu H, Li C, Shi W, Du Z, Gao Y.

Cytotherapy. 2018 Jan;20(1):95-107. doi: 10.1016/j.jcyt.2017.08.008. Epub 2017 Sep 29.


Bioprinting of human pluripotent stem cells and their directed differentiation into hepatocyte-like cells for the generation of mini-livers in 3D.

Faulkner-Jones A, Fyfe C, Cornelissen DJ, Gardner J, King J, Courtney A, Shu W.

Biofabrication. 2015 Oct 21;7(4):044102. doi: 10.1088/1758-5090/7/4/044102.


Regulation of Human Pluripotent Stem Cell-Derived Hepatic Cell Phenotype by Three-Dimensional Hydrogel Models.

Toivonen S, Malinen MM, Küblbeck J, Petsalo A, Urtti A, Honkakoski P, Otonkoski T.

Tissue Eng Part A. 2016 Jul;22(13-14):971-84. doi: 10.1089/ten.TEA.2016.0127. Epub 2016 Jul 7.


Functional comparison of human embryonic stem cells and induced pluripotent stem cells as sources of hepatocyte-like cells.

Jeong J, Kim KN, Chung MS, Kim HJ.

Tissue Eng Regen Med. 2016 Dec 17;13(6):740-749. doi: 10.1007/s13770-016-0094-y. eCollection 2016 Dec.


Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes.

Xu Z, He X, Shi X, Xia Y, Liu X, Wu H, Li P, Zhang H, Yin W, Du X, Li L, Li Y.

Stem Cell Res Ther. 2018 Aug 9;9(1):211. doi: 10.1186/s13287-018-0940-z.


Generation of hepatobiliary organoids from human induced pluripotent stem cells.

Wu F, Wu D, Ren Y, Huang Y, Feng B, Zhao N, Zhang T, Chen X, Chen S, Xu A.

J Hepatol. 2019 Jun;70(6):1145-1158. doi: 10.1016/j.jhep.2018.12.028. Epub 2019 Jan 7.


Generation of functional hepatocyte-like cells from human pluripotent stem cells in a scalable suspension culture.

Vosough M, Omidinia E, Kadivar M, Shokrgozar MA, Pournasr B, Aghdami N, Baharvand H.

Stem Cells Dev. 2013 Oct 15;22(20):2693-705. doi: 10.1089/scd.2013.0088. Epub 2013 Jul 9.


Mouse decellularised liver scaffold improves human embryonic and induced pluripotent stem cells differentiation into hepatocyte-like cells.

Lorvellec M, Scottoni F, Crowley C, Fiadeiro R, Maghsoudlou P, Pellegata AF, Mazzacuva F, Gjinovci A, Lyne AM, Zulini J, Little D, Mosaku O, Kelly D, De Coppi P, Gissen P.

PLoS One. 2017 Dec 20;12(12):e0189586. doi: 10.1371/journal.pone.0189586. eCollection 2017.


Disease-corrected hepatocyte-like cells from familial hypercholesterolemia-induced pluripotent stem cells.

Fattahi F, Asgari S, Pournasr B, Seifinejad A, Totonchi M, Taei A, Aghdami N, Salekdeh GH, Baharvand H.

Mol Biotechnol. 2013 Jul;54(3):863-73. doi: 10.1007/s12033-012-9635-3.


Efficient Production of Hepatocyte-like Cells from Human-induced Pluripotent Stem Cells by Optimizing Growth Factors.

Jafarpour Z, Soleimani M, Hosseinkhani S, M H MH, Yaghmaei P, Mobarra N, Geramizadeh B.

Int J Organ Transplant Med. 2018;9(2):77-87. Epub 2018 May 1.


In situ differentiation and generation of functional liver organoids from human iPSCs in a 3D perfusable chip system.

Wang Y, Wang H, Deng P, Chen W, Guo Y, Tao T, Qin J.

Lab Chip. 2018 Dec 7;18(23):3606-3616. doi: 10.1039/c8lc00869h. Epub 2018 Oct 25.


Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.

Heslop JA, Kia R, Pridgeon CS, Sison-Young RL, Liloglou T, Elmasry M, Fenwick SW, Mills JS, Kitteringham NR, Goldring CE, Park BK.

Stem Cells Transl Med. 2017 May;6(5):1321-1331. doi: 10.1002/sctm.16-0029. Erratum in: Stem Cells Transl Med. 2017 Aug;6(8):1751.


Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions.

Xia Y, Carpentier A, Cheng X, Block PD, Zhao Y, Zhang Z, Protzer U, Liang TJ.

J Hepatol. 2017 Mar;66(3):494-503. doi: 10.1016/j.jhep.2016.10.009. Epub 2016 Oct 14.

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