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Moderate Hypothermic Circulatory Arrest Is Preferable During Cardiopulmonary Bypass.

Gong M, Li L, Liu Y, Xu S, Dai L, Liu Y, Li H, Wang X, Guan X, Zhang H.

Ther Hypothermia Temp Manag. 2019 Jun 18. doi: 10.1089/ther.2019.0005. [Epub ahead of print]


Moderate and deep hypothermic circulatory arrest has a comparable effect on acute kidney injury after total arch replacement with frozen elephant trunk procedure in type A aortic dissection.

Fang Z, Wang G, Liu Q, Zhou H, Zhou S, Lei G, Zhang C, Yang L, Shi S, Li J, Qian X, Sun X, Wei B, Yu C.

Interact Cardiovasc Thorac Surg. 2019 Jul 1;29(1):130-136. doi: 10.1093/icvts/ivz092.


Moderate Versus Deep Hypothermia With Unilateral Selective Antegrade Cerebral Perfusion for Acute Type A Dissection.

Leshnower BG, Thourani VH, Halkos ME, Sarin EL, Keeling WB, Lamias MJ, Guyton RA, Chen EP.

Ann Thorac Surg. 2015 Nov;100(5):1563-8; discussion 1568-9. doi: 10.1016/j.athoracsur.2015.05.032. Epub 2015 Jul 30.


Moderate versus deep hypothermic circulatory arrest for elective aortic transverse hemiarch reconstruction.

Vallabhajosyula P, Jassar AS, Menon RS, Komlo C, Gutsche J, Desai ND, Hargrove WC, Bavaria JE, Szeto WY.

Ann Thorac Surg. 2015 May;99(5):1511-7. doi: 10.1016/j.athoracsur.2014.12.067. Epub 2015 Mar 29.


Deep Hypothermia With Retrograde Cerebral Perfusion Versus Moderate Hypothermia With Antegrade Cerebral Perfusion for Arch Surgery.

Leshnower BG, Rangaraju S, Allen JW, Stringer AY, Gleason TG, Chen EP.

Ann Thorac Surg. 2019 Apr;107(4):1104-1110. doi: 10.1016/j.athoracsur.2018.10.008. Epub 2018 Nov 15.


Modified hypothermic circulatory arrest for emergent repair of acute aortic dissection type a: a single-center experience.

Qian H, Hu J, Du L, Xue Y, Meng W, Zhang EY.

J Cardiothorac Surg. 2013 May 9;8:125. doi: 10.1186/1749-8090-8-125.


The Impact of Deep Versus Moderate Hypothermia on Postoperative Kidney Function After Elective Aortic Hemiarch Repair.

Arnaoutakis GJ, Vallabhajosyula P, Bavaria JE, Sultan I, Siki M, Naidu S, Milewski RK, Williams ML, Hargrove WC 3rd, Desai ND, Szeto WY.

Ann Thorac Surg. 2016 Oct;102(4):1313-21. doi: 10.1016/j.athoracsur.2016.04.007. Epub 2016 Jun 16.


A meta-analysis of deep hypothermic circulatory arrest versus moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion.

Tian DH, Wan B, Bannon PG, Misfeld M, LeMaire SA, Kazui T, Kouchoukos NT, Elefteriades JA, Bavaria J, Coselli JS, Griepp RB, Mohr FW, Oo A, Svensson LG, Hughes GC, Yan TD.

Ann Cardiothorac Surg. 2013 Mar;2(2):148-58. doi: 10.3978/j.issn.2225-319X.2013.03.13.


Moderate hypothermic circulatory arrest in total arch repair for acute type A aortic dissection: clinical safety and efficacy.

Gong M, Ma WG, Guan XL, Wang LF, Li JC, Lan F, Sun LZ, Zhang HJ.

J Thorac Dis. 2016 May;8(5):925-33. doi: 10.21037/jtd.2016.02.75.


Moderate Hypothermia Provides Better Protection of the Intestinal Barrier than Deep Hypothermia during Circulatory Arrest in a Piglet Model: A Microdialysis Study.

Liang M, Feng K, Yang X, Chen G, Tang Z, Lin W, Rong J, Wu Z.

PLoS One. 2016 Sep 29;11(9):e0163684. doi: 10.1371/journal.pone.0163684. eCollection 2016.


Moderate hypothermia during aortic arch surgery is associated with reduced risk of early mortality.

Tsai JY, Pan W, Lemaire SA, Pisklak P, Lee VV, Bracey AW, Elayda MA, Preventza O, Price MD, Collard CD, Coselli JS.

J Thorac Cardiovasc Surg. 2013 Sep;146(3):662-7. doi: 10.1016/j.jtcvs.2013.03.004. Epub 2013 Apr 1.


Retrograde and antegrade cerebral perfusion: results in short elective arch reconstructive times.

Milewski RK, Pacini D, Moser GW, Moeller P, Cowie D, Szeto WY, Woo YJ, Desai N, Di Marco L, Pochettino A, Di Bartolomeo R, Bavaria JE.

Ann Thorac Surg. 2010 May;89(5):1448-57. doi: 10.1016/j.athoracsur.2010.01.056.


Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement.

Keeling WB, Tian DH, Leshnower BG, Numata S, Hughes GC, Matalanis G, Okita Y, Yan TD, Kouchoukos N, Chen EP; IAASSG Investigators.

Ann Thorac Surg. 2018 Jan;105(1):54-61. doi: 10.1016/j.athoracsur.2017.06.072. Epub 2017 Nov 20.


Effect of granulocyte-colony stimulating factor on expression of selected proteins involved in regulation of apoptosis in the brain of newborn piglets after cardiopulmonary bypass and deep hypothermic circulatory arrest.

Pastuszko P, Schears GJ, Pirzadeh A, Kubin J, Greeley WJ, Wilson DF, Pastuszko A.

J Thorac Cardiovasc Surg. 2012 Jun;143(6):1436-42. doi: 10.1016/j.jtcvs.2012.01.018. Epub 2012 Feb 4.


Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.

Jiang X, Gu T, Liu Y, Gao S, Shi E, Zhang G.

Ther Hypothermia Temp Manag. 2019 Jun;9(2):118-127. doi: 10.1089/ther.2018.0013. Epub 2018 Jul 23.


Postoperative hypoxemia exacerbates potential brain injury after deep hypothermic circulatory arrest.

Tsui SS, Schultz JM, Shen I, Ungerleider RM.

Ann Thorac Surg. 2004 Jul;78(1):188-96; discussion 188-96.


Antegrade cerebral perfusion during deep hypothermia circulatory arrest attenuates the apoptosis of neurons in porcine hippocampus.

Zhao R, Cui Q, Yu SQ, Sun GC, Wang HB, Jin ZX, Gu CH, Yi DH.

Heart Surg Forum. 2009 Aug;12(4):E219-24. doi: 10.1532/HSF98.20091018.


Proteomics of cerebral injury in a neonatal model of cardiopulmonary bypass with deep hypothermic circulatory arrest.

Sheikh AM, Barrett C, Villamizar N, Alzate O, Miller S, Shelburne J, Lodge A, Lawson J, Jaggers J.

J Thorac Cardiovasc Surg. 2006 Oct;132(4):820-8. Epub 2006 Sep 1.


Evaluation of cerebral metabolism and quantitative electroencephalography after hypothermic circulatory arrest and low-flow cardiopulmonary bypass at different temperatures.

Mezrow CK, Midulla PS, Sadeghi AM, Gandsas A, Wang W, Dapunt OE, Zappulla R, Griepp RB.

J Thorac Cardiovasc Surg. 1994 Apr;107(4):1006-19.


Cardiac surgery with deep hypothermic circulatory arrest produces less systemic inflammatory response than low-flow cardiopulmonary bypass in newborns.

Tassani P, Barankay A, Haas F, Paek SU, Heilmaier M, Hess J, Lange R, Richter JA.

J Thorac Cardiovasc Surg. 2002 Apr;123(4):648-54.

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