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Items: 1 to 20 of 101

1.

Impacts of particle shapes on the oral delivery of drug nanocrystals: Mucus permeation, transepithelial transport and bioavailability.

Guo M, Wei M, Li W, Guo M, Guo C, Ma M, Wang Y, Yang Z, Li M, Fu Q, Yang L, He Z.

J Control Release. 2019 Jun 15;307:64-75. doi: 10.1016/j.jconrel.2019.06.015. [Epub ahead of print]

PMID:
31207275
2.

Transmembrane Pathways and Mechanisms of Rod-like Paclitaxel Nanocrystals through MDCK Polarized Monolayer.

Deng F, Zhang H, Wang X, Zhang Y, Hu H, Song S, Dai W, He B, Zheng Y, Wang X, Zhang Q.

ACS Appl Mater Interfaces. 2017 Feb 22;9(7):5803-5816. doi: 10.1021/acsami.6b15151. Epub 2017 Feb 9.

PMID:
28116899
3.

Oral Delivery of Puerarin Nanocrystals To Improve Brain Accumulation and Anti-Parkinsonian Efficacy.

Xiong S, Liu W, Li D, Chen X, Liu F, Yuan D, Pan H, Wang Q, Fang S, Chen T.

Mol Pharm. 2019 Apr 1;16(4):1444-1455. doi: 10.1021/acs.molpharmaceut.8b01012. Epub 2019 Mar 6.

PMID:
30811206
4.

Preparation and in-vitro/in-vivo characterization of trans-resveratrol nanocrystals for oral administration.

Singh SK, Makadia V, Sharma S, Rashid M, Shahi S, Mishra PR, Wahajuddin M, Gayen JR.

Drug Deliv Transl Res. 2017 Jun;7(3):395-407. doi: 10.1007/s13346-017-0362-y.

PMID:
28194730
5.

Development of surface stabilized candesartan cilexetil nanocrystals with enhanced dissolution rate, permeation rate across CaCo-2, and oral bioavailability.

Jain S, Reddy VA, Arora S, Patel K.

Drug Deliv Transl Res. 2016 Oct;6(5):498-510. doi: 10.1007/s13346-016-0297-8.

PMID:
27129488
6.

In vitro and in vivo evaluation of SN-38 nanocrystals with different particle sizes.

Chen M, Li W, Zhang X, Dong Y, Hua Y, Zhang H, Gao J, Zhao L, Li Y, Zheng A.

Int J Nanomedicine. 2017 Aug 1;12:5487-5500. doi: 10.2147/IJN.S133816. eCollection 2017.

7.

Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine.

Xiong W, Sang W, Linghu KG, Zhong ZF, Cheang WS, Li J, Hu YJ, Yu H, Wang YT.

Int J Nanomedicine. 2018 Jun 28;13:3781-3793. doi: 10.2147/IJN.S163763. eCollection 2018.

8.

Pharmaceutical and pharmacokinetic characteristics of different types of fenofibrate nanocrystals prepared by different bottom-up approaches.

Zhang H, Meng Y, Wang X, Dai W, Wang X, Zhang Q.

Drug Deliv. 2014 Dec;21(8):588-94. doi: 10.3109/10717544.2013.865815. Epub 2013 Dec 9.

PMID:
24320001
9.

Transport Mechanism of Coumarin 6 Nanocrystals with Two Particle Sizes in MDCKII Monolayer and Larval Zebrafish.

Miao X, Li Y, Wang X, Lee SM, Zheng Y.

ACS Appl Mater Interfaces. 2016 May 25;8(20):12620-30. doi: 10.1021/acsami.6b01680. Epub 2016 May 16.

PMID:
27159431
10.

Enhanced transport of nanocage stabilized pure nanodrug across intestinal epithelial barrier mimicking Listeria monocytogenes.

Xia D, Tao J, He Y, Zhu Q, Chen D, Yu M, Cui F, Gan Y.

Biomaterials. 2015 Jan;37:320-32. doi: 10.1016/j.biomaterials.2014.10.038. Epub 2014 Oct 25.

PMID:
25453961
11.

Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms.

Silva E, Barreiros L, Segundo MA, Costa Lima SA, Reis S.

Acta Biomater. 2017 Apr 15;53:439-449. doi: 10.1016/j.actbio.2017.01.057. Epub 2017 Jan 22.

PMID:
28119111
12.

Overcoming multiple gastrointestinal barriers by bilayer modified hollow mesoporous silica nanocarriers.

Wang Y, Zhao Y, Cui Y, Zhao Q, Zhang Q, Musetti S, Kinghorn KA, Wang S.

Acta Biomater. 2018 Jan;65:405-416. doi: 10.1016/j.actbio.2017.10.025. Epub 2017 Oct 14. Erratum in: Acta Biomater. 2018 Feb 21;:.

PMID:
29037897
13.

Enhanced oral absorption and anticancer efficacy of cabazitaxel by overcoming intestinal mucus and epithelium barriers using surface polyethylene oxide (PEO) decorated positively charged polymer-lipid hybrid nanoparticles.

Ren T, Wang Q, Xu Y, Cong L, Gou J, Tao X, Zhang Y, He H, Yin T, Zhang H, Zhang Y, Tang X.

J Control Release. 2018 Jan 10;269:423-438. doi: 10.1016/j.jconrel.2017.11.015. Epub 2017 Nov 11.

PMID:
29133120
14.

Investigating the role of Pluronic-g-Cationic polyelectrolyte as functional stabilizer for nanocrystals: Impact on Paclitaxel oral bioavailability and tumor growth.

Sharma S, Verma A, Pandey G, Mittapelly N, Mishra PR.

Acta Biomater. 2015 Oct;26:169-83. doi: 10.1016/j.actbio.2015.08.005. Epub 2015 Aug 8.

PMID:
26265061
15.

Rod shaped nanocrystals exhibit superior in vitro dissolution and in vivo bioavailability over spherical like nanocrystals: a case study of lovastatin.

Guo M, Fu Q, Wu C, Guo Z, Li M, Sun J, He Z, Yang L.

Colloids Surf B Biointerfaces. 2015 Apr 1;128:410-418. doi: 10.1016/j.colsurfb.2015.02.039. Epub 2015 Feb 25.

PMID:
25766921
16.

Spironolactone nanocrystals for oral administration: Different pharmacokinetic performances induced by stabilizers.

Mu S, Li M, Guo M, Yang W, Wang Y, Li J, Fu Q, He Z.

Colloids Surf B Biointerfaces. 2016 Nov 1;147:73-80. doi: 10.1016/j.colsurfb.2016.07.051. Epub 2016 Jul 28.

PMID:
27490456
17.

Preparation and Evaluation of Diosgenin Nanocrystals to Improve Oral Bioavailability.

Liu CZ, Chang JH, Zhang L, Xue HF, Liu XG, Liu P, Fu Q.

AAPS PharmSciTech. 2017 Aug;18(6):2067-2076. doi: 10.1208/s12249-016-0684-y. Epub 2016 Dec 19.

PMID:
27995466
18.

Formulation of nimodipine nanocrystals for oral administration.

Li J, Fu Q, Liu X, Li M, Wang Y.

Arch Pharm Res. 2016 Feb;39(2):202-212. doi: 10.1007/s12272-015-0685-5. Epub 2015 Nov 19.

PMID:
26584914
19.

Overcoming the diffusion barrier of mucus and absorption barrier of epithelium by self-assembled nanoparticles for oral delivery of insulin.

Shan W, Zhu X, Liu M, Li L, Zhong J, Sun W, Zhang Z, Huang Y.

ACS Nano. 2015 Mar 24;9(3):2345-56. doi: 10.1021/acsnano.5b00028. Epub 2015 Feb 10.

PMID:
25658958
20.

Improved oral bioavailability for lutein by nanocrystal technology: formulation development, in vitro and in vivo evaluation.

Chang D, Ma Y, Cao G, Wang J, Zhang X, Feng J, Wang W.

Artif Cells Nanomed Biotechnol. 2018 Aug;46(5):1018-1024. doi: 10.1080/21691401.2017.1358732. Epub 2017 Jul 27.

PMID:
28749189

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