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Items: 1 to 20 of 98

1.

SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway.

Gu X, Jiang Y, Xue W, Song C, Wang Y, Liu Y, Cui B.

Clin Exp Pharmacol Physiol. 2019 Jun 17. doi: 10.1111/1440-1681.13124. [Epub ahead of print]

PMID:
31206801
2.

Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration.

Bradley E, Dasgupta S, Jiang X, Zhao X, Zhu G, He Q, Dinkins M, Bieberich E, Wang G.

PLoS One. 2014 Oct 20;9(10):e110119. doi: 10.1371/journal.pone.0110119. eCollection 2014.

3.

Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium.

Fu P, Ebenezer DL, Berdyshev EV, Bronova IA, Shaaya M, Harijith A, Natarajan V.

J Biol Chem. 2016 Dec 30;291(53):27187-27203. doi: 10.1074/jbc.M116.758946. Epub 2016 Nov 18.

4.

Sphingosine-1-phosphate promotes the proliferation and attenuates apoptosis of Endothelial progenitor cells via S1PR1/S1PR3/PI3K/Akt pathway.

Wang H, Huang H, Ding SF.

Cell Biol Int. 2018 Nov;42(11):1492-1502. doi: 10.1002/cbin.10991. Epub 2018 Jul 8.

PMID:
29790626
5.

CLDN8 promotes colorectal cancer cell proliferation, migration, and invasion by activating MAPK/ERK signaling.

Cheng B, Rong A, Zhou Q, Li W.

Cancer Manag Res. 2019 Apr 30;11:3741-3751. doi: 10.2147/CMAR.S189558. eCollection 2019.

6.

TMEM206 promotes the malignancy of colorectal cancer cells by interacting with AKT and extracellular signal-regulated kinase signaling pathways.

Zhao J, Zhu D, Zhang X, Zhang Y, Zhou J, Dong M.

J Cell Physiol. 2019 Jul;234(7):10888-10898. doi: 10.1002/jcp.27751. Epub 2018 Nov 11.

PMID:
30417481
7.

NCOA5 promotes proliferation, migration and invasion of colorectal cancer cells via activation of PI3K/AKT pathway.

Sun K, Wang S, He J, Xie Y, He Y, Wang Z, Qin L.

Oncotarget. 2017 Nov 14;8(64):107932-107946. doi: 10.18632/oncotarget.22429. eCollection 2017 Dec 8.

8.

S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis.

Fang C, Bian G, Ren P, Xiang J, Song J, Yu C, Zhang Q, Liu L, Chen K, Liu F, Zhang K, Wu C, Sun R, Hu D, Ju G, Wang J.

FASEB J. 2018 Jul;32(7):3597-3613. doi: 10.1096/fj.201701116R. Epub 2018 Feb 8.

PMID:
29452570
9.

Sphingosine-1-phosphate mediates AKT/ERK maintenance of dental pulp homoeostasis.

Pan HY, Yang H, Shao MY, Xu J, Zhang P, Cheng R, Hu T.

Int Endod J. 2015 May;48(5):460-8. doi: 10.1111/iej.12335. Epub 2014 Jul 15.

PMID:
24931601
10.

Lipid transporter Spns2 promotes microglia pro-inflammatory activation in response to amyloid-beta peptide.

Zhong L, Jiang X, Zhu Z, Qin H, Dinkins MB, Kong JN, Leanhart S, Wang R, Elsherbini A, Bieberich E, Zhao Y, Wang G.

Glia. 2019 Mar;67(3):498-511. doi: 10.1002/glia.23558. Epub 2018 Nov 28.

PMID:
30484906
11.

Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells.

Hisano Y, Kobayashi N, Yamaguchi A, Nishi T.

PLoS One. 2012;7(6):e38941. doi: 10.1371/journal.pone.0038941. Epub 2012 Jun 12.

12.

Biological function of SPNS2: From zebrafish to human.

Zhu X, Ren K, Zeng YZ, Zheng Z, Yi GH.

Mol Immunol. 2018 Nov;103:55-62. doi: 10.1016/j.molimm.2018.08.025. Epub 2018 Sep 6. Review.

PMID:
30196234
13.

Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts.

Laurenzana A, Cencetti F, Serratì S, Bruno G, Japtok L, Bianchini F, Torre E, Fibbi G, Del Rosso M, Bruni P, Donati C.

J Mol Med (Berl). 2015 Oct;93(10):1145-57. doi: 10.1007/s00109-015-1292-0. Epub 2015 May 9.

PMID:
25952146
14.
16.

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice.

Fukuhara S, Simmons S, Kawamura S, Inoue A, Orba Y, Tokudome T, Sunden Y, Arai Y, Moriwaki K, Ishida J, Uemura A, Kiyonari H, Abe T, Fukamizu A, Hirashima M, Sawa H, Aoki J, Ishii M, Mochizuki N.

J Clin Invest. 2012 Apr;122(4):1416-26. doi: 10.1172/JCI60746. Epub 2012 Mar 12.

17.

Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells.

Blanchard O, Stepanovska B, Starck M, Erhardt M, Römer I, Meyer Zu Heringdorf D, Pfeilschifter J, Zangemeister-Wittke U, Huwiler A.

Int J Mol Sci. 2018 May 17;19(5). pii: E1498. doi: 10.3390/ijms19051498.

18.

The protective role of all-transretinoic acid (ATRA) against colorectal cancer development is achieved via increasing miR-3666 expression and decreasing E2F7 expression.

Liu W, Song Y, Zhang C, Gao P, Huang B, Yang J.

Biomed Pharmacother. 2018 Aug;104:94-101. doi: 10.1016/j.biopha.2018.05.015. Epub 2018 May 14.

PMID:
29772445
19.

The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors.

Kawahara A, Nishi T, Hisano Y, Fukui H, Yamaguchi A, Mochizuki N.

Science. 2009 Jan 23;323(5913):524-7. doi: 10.1126/science.1167449. Epub 2008 Dec 11.

20.

Sphingosine 1-phosphate stimulates eyelid closure in the developing rat by stimulating EGFR signaling.

Bian G, Yu C, Liu L, Fang C, Chen K, Ren P, Zhang Q, Liu F, Zhang K, Xue Q, Xiang J, Guo H, Song J, Zhao Y, Wu W, Chung SK, Sun R, Ju G, Wang J.

Sci Signal. 2018 Oct 23;11(553). pii: eaat1470. doi: 10.1126/scisignal.aat1470.

PMID:
30352949

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