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Angiotensin I-converting enzyme gene plays a crucial role in the pathology of carcinomas in colorectal cancer.

Zhang K, Mao T, He Z, Wu X, Peng Y, Chen Y, Dong Y, Ruan Z, Wang Z.

Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):2500-2506. doi: 10.1080/21691401.2019.1626402.


The clinicopathological significance of HES1 promoter hypomethylation in patients with colorectal cancer.

Wu Y, Gong L, Xu J, Mou Y, Xu X, Qian Z.

Onco Targets Ther. 2017 Dec 8;10:5827-5834. doi: 10.2147/OTT.S151857. eCollection 2017.


Cadherin-11 is inactivated due to promoter methylation and functions in colorectal cancer as a tumour suppressor.

Yuan S, Li L, Xiang S, Jia H, Luo T.

Cancer Manag Res. 2019 Mar 28;11:2517-2529. doi: 10.2147/CMAR.S193921. eCollection 2019.


Prognostic Values of EPDR1 Hypermethylation and Its Inhibitory Function on Tumor Invasion in Colorectal Cancer.

Chu CH, Chang SC, Wang HH, Yang SH, Lai KC, Lee TC.

Cancers (Basel). 2018 Oct 22;10(10). pii: E393. doi: 10.3390/cancers10100393.


Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth.

Wang Y, He T, Herman JG, Linghu E, Yang Y, Fuks F, Zhou F, Song L, Guo M.

Clin Epigenetics. 2017 Oct 18;9:115. doi: 10.1186/s13148-017-0417-4. eCollection 2017. Erratum in: Clin Epigenetics. 2018 Mar 14;10 :36.


Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis.

Hur K, Cejas P, Feliu J, Moreno-Rubio J, Burgos E, Boland CR, Goel A.

Gut. 2014 Apr;63(4):635-46. doi: 10.1136/gutjnl-2012-304219. Epub 2013 May 23.


Up-regulated expression of SNHG6 predicts poor prognosis in colorectal cancer.

Li M, Bian Z, Yao S, Zhang J, Jin G, Wang X, Yin Y, Huang Z.

Pathol Res Pract. 2018 May;214(5):784-789. doi: 10.1016/j.prp.2017.12.014. Epub 2018 Jan 3.


The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer.

Savio AJ, Mrkonjic M, Lemire M, Gallinger S, Knight JA, Bapat B.

Clin Epigenetics. 2017 Mar 9;9:26. doi: 10.1186/s13148-017-0326-6. eCollection 2017.


Long non-coding RNA RUNX1-IT1 plays a tumour-suppressive role in colorectal cancer by inhibiting cell proliferation and migration.

Shi J, Zhong X, Song Y, Wu Z, Gao P, Zhao J, Sun J, Wang J, Liu J, Wang Z.

Cell Biochem Funct. 2019 Jan;37(1):11-20. doi: 10.1002/cbf.3368. Epub 2018 Nov 30.


The association between ACE polymorphism and risk of colorectal cancer in a Chinese population.

Liu SY, Sima X, Wang CH, Gao M.

Clin Biochem. 2011 Oct;44(14-15):1223-6. doi: 10.1016/j.clinbiochem.2011.07.016. Epub 2011 Aug 6.


Hypermethylation and prognostic implication of Syk gene in human colorectal cancer.

Yang Z, Huo L, Chen H, Ni B, Xiang J, Kang L, Wang L, Peng J, Yuan Y, Wang J.

Med Oncol. 2013;30(2):586. doi: 10.1007/s12032-013-0586-8. Epub 2013 Apr 23.


Promoter methylation and expression of SOCS-1 affect clinical outcome and epithelial-mesenchymal transition in colorectal cancer.

Kang XC, Chen ML, Yang F, Gao BQ, Yang QH, Zheng WW, Hao S.

Biomed Pharmacother. 2016 May;80:23-29. doi: 10.1016/j.biopha.2016.02.011. Epub 2016 Mar 14.


Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo.

Yang S, Li W, Sun H, Wu B, Ji F, Sun T, Chang H, Shen P, Wang Y, Zhou D.

BMC Cancer. 2015 Dec 16;15:969. doi: 10.1186/s12885-015-1958-6.


Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.

Gao D, Han Y, Yang Y, Herman JG, Linghu E, Zhan Q, Fuks F, Lu ZJ, Guo M.

Epigenetics. 2017 Jul 3;12(7):575-583. doi: 10.1080/15592294.2017.1341027. Epub 2017 Jul 5.


Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer.

Kaneko M, Kotake M, Bando H, Yamada T, Takemura H, Minamoto T.

BMC Cancer. 2016 Dec 12;16(1):945.


Long non-coding RNA FOXP4-AS1 is an unfavourable prognostic factor and regulates proliferation and apoptosis in colorectal cancer.

Li J, Lian Y, Yan C, Cai Z, Ding J, Ma Z, Peng P, Wang K.

Cell Prolif. 2017 Feb;50(1). doi: 10.1111/cpr.12312. Epub 2016 Oct 27.


Decreased expression of semaphorin 3D is associated with genesis and development in colorectal cancer.

Wang Z, Ding M, Qian N, Song B, Yu J, Tang J, Wang J.

World J Surg Oncol. 2017 Mar 20;15(1):67. doi: 10.1186/s12957-017-1128-1.


Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer.

Yan W, Wu K, Herman JG, Xu X, Yang Y, Dai G, Guo M.

Clin Epigenetics. 2018 May 23;10:69. doi: 10.1186/s13148-018-0501-4. eCollection 2018.


Antihypertensives as novel antineoplastics: angiotensin-I-converting enzyme inhibitors and angiotensin II type 1 receptor blockers in pancreatic ductal adenocarcinoma.

Arafat HA, Gong Q, Chipitsyna G, Rizvi A, Saa CT, Yeo CJ.

J Am Coll Surg. 2007 May;204(5):996-1005; discussion 1005-6.


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