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Items: 1 to 20 of 113


Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury.

Liu Y, Lu T, Zhang C, Xu J, Xue Z, Busuttil RW, Xu N, Xia Q, Kupiec-Weglinski JW, Ji H.

J Hepatol. 2019 Jun 13. pii: S0168-8278(19)30344-7. doi: 10.1016/j.jhep.2019.05.029. [Epub ahead of print]


Pituitary Adenylate Cyclase-Activating Polypeptides Prevent Hepatocyte Damage by Promoting Yes-associated Protein in Liver Ischemia/Reperfusion Injury.

Liu Y, Lu T, Zhang C, Xue Z, Xu J, Busuttil RW, Xia Q, Xu N, Kupiec-Weglinski JW, Ji H.

Transplantation. 2019 Apr 8. doi: 10.1097/TP.0000000000002742. [Epub ahead of print]


KEAP1-NRF2 complex in ischemia-induced hepatocellular damage of mouse liver transplants.

Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW.

J Hepatol. 2013 Dec;59(6):1200-7. doi: 10.1016/j.jhep.2013.07.016. Epub 2013 Jul 16.


Vasoactive intestinal peptide attenuates liver ischemia/reperfusion injury in mice via the cyclic adenosine monophosphate-protein kinase a pathway.

Ji H, Zhang Y, Liu Y, Shen XD, Gao F, Nguyen TT, Busuttil RW, Waschek JA, Kupiec-Weglinski JW.

Liver Transpl. 2013 Sep;19(9):945-56. doi: 10.1002/lt.23681. Epub 2013 Jul 26.


Macrophage heme oxygenase-1-SIRT1-p53 axis regulates sterile inflammation in liver ischemia-reperfusion injury.

Nakamura K, Zhang M, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Araujo JA, Kupiec-Weglinski JW.

J Hepatol. 2017 Dec;67(6):1232-1242. doi: 10.1016/j.jhep.2017.08.010. Epub 2017 Aug 23.


Neuropeptide PACAP in mouse liver ischemia and reperfusion injury: immunomodulation by the cAMP-PKA pathway.

Ji H, Zhang Y, Shen XD, Gao F, Huang CY, Abad C, Busuttil RW, Waschek JA, Kupiec-Weglinski JW.

Hepatology. 2013 Mar;57(3):1225-37. doi: 10.1002/hep.25802. Epub 2013 Jan 18.


A Soluble Form of P Selectin Glycoprotein Ligand 1 Requires Signaling by Nuclear Factor Erythroid 2-Related Factor 2 to Protect Liver Transplant Endothelial Cells Against Ischemia-Reperfusion Injury.

Zhang C, Zhang Y, Liu Y, Liu Y, Kageyama S, Shen XD, Gao F, Zheng S, Busuttil RW, Shaw GD, Ji H, Kupiec-Weglinski JW.

Am J Transplant. 2017 Jun;17(6):1462-1475. doi: 10.1111/ajt.14159. Epub 2017 Feb 6.


Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and regeneration after liver ischemia-reperfusion injury.

Konishi T, Schuster RM, Lentsch AB.

Am J Physiol Gastrointest Liver Physiol. 2018 Apr 1;314(4):G471-G482. doi: 10.1152/ajpgi.00153.2017. Epub 2018 Jan 11.


Recombinant relaxin protects liver transplants from ischemia damage by hepatocyte glucocorticoid receptor: From bench-to-bedside.

Kageyama S, Nakamura K, Fujii T, Ke B, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW.

Hepatology. 2018 Jul;68(1):258-273. doi: 10.1002/hep.29787. Epub 2018 May 10.


Nuclear factor erythroid 2-related factor 2 regulates toll-like receptor 4 innate responses in mouse liver ischemia-reperfusion injury through Akt-forkhead box protein O1 signaling network.

Huang J, Yue S, Ke B, Zhu J, Shen XD, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW.

Transplantation. 2014 Oct 15;98(7):721-8. doi: 10.1097/TP.0000000000000316.


Activation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in mice.

Ji H, Shen XD, Zhang Y, Gao F, Huang CY, Chang WW, Lee C, Ke B, Busuttil RW, Kupiec-Weglinski JW.

Liver Transpl. 2012 Jun;18(6):659-70. doi: 10.1002/lt.23399.


Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

Liu Y, Ji H, Zhang Y, Shen X, Gao F, He X, Li GA, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW.

J Hepatol. 2015 Mar;62(3):563-72. doi: 10.1016/j.jhep.2014.10.034. Epub 2014 Oct 31.


Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human.

Nakamura K, Kageyama S, Ke B, Fujii T, Sosa RA, Reed EF, Datta N, Zarrinpar A, Busuttil RW, Kupiec-Weglinski JW.

Liver Transpl. 2017 Oct;23(10):1282-1293. doi: 10.1002/lt.24821.


ATF3-mediated NRF2/HO-1 signaling regulates TLR4 innate immune responses in mouse liver ischemia/reperfusion injury.

Rao J, Qian X, Li G, Pan X, Zhang C, Zhang F, Zhai Y, Wang X, Lu L.

Am J Transplant. 2015 Jan;15(1):76-87. doi: 10.1111/ajt.12954. Epub 2014 Oct 30.


Serelaxin induces Notch1 signaling and alleviates hepatocellular damage in orthotopic liver transplantation.

Kageyama S, Nakamura K, Ke B, Busuttil RW, Kupiec-Weglinski JW.

Am J Transplant. 2018 Jul;18(7):1755-1763. doi: 10.1111/ajt.14706. Epub 2018 Mar 23.


T-cell immunoglobulin and mucin domain 4 (TIM-4) signaling in innate immune-mediated liver ischemia-reperfusion injury.

Ji H, Liu Y, Zhang Y, Shen XD, Gao F, Busuttil RW, Kuchroo VK, Kupiec-Weglinski JW.

Hepatology. 2014 Dec;60(6):2052-2064. doi: 10.1002/hep.27334. Epub 2014 Oct 29.


Hippo Signaling Controls NLR Family Pyrin Domain Containing 3 Activation and Governs Immunoregulation of Mesenchymal Stem Cells in Mouse Liver Injury.

Li C, Jin Y, Wei S, Sun Y, Jiang L, Zhu Q, Farmer DG, Busuttil RW, Kupiec-Weglinski JW, Ke B.

Hepatology. 2019 May 7. doi: 10.1002/hep.30700. [Epub ahead of print]


Targeting TIM-1 on CD4 T cells depresses macrophage activation and overcomes ischemia-reperfusion injury in mouse orthotopic liver transplantation.

Zhang Y, Ji H, Shen X, Cai J, Gao F, Koenig KM, Batikian CM, Busuttil RW, Kupiec-Weglinski JW.

Am J Transplant. 2013 Jan;13(1):56-66. doi: 10.1111/j.1600-6143.2012.04316.x. Epub 2012 Nov 8.


The Hippo pathway effector YAP controls mouse hepatic stellate cell activation.

Mannaerts I, Leite SB, Verhulst S, Claerhout S, Eysackers N, Thoen LF, Hoorens A, Reynaert H, Halder G, van Grunsven LA.

J Hepatol. 2015 Sep;63(3):679-88. doi: 10.1016/j.jhep.2015.04.011. Epub 2015 Apr 20.


Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice.

Yaron JR, Chen H, Ambadapadi S, Zhang L, Tafoya AM, Munk BH, Wakefield DN, Fuentes J, Marques BJ, Harripersaud K, Bartee MY, Davids JA, Zheng D, Rand K, Dixon L, Moyer RW, Clapp WL, Lucas AR.

J Inflamm (Lond). 2019 May 29;16:12. doi: 10.1186/s12950-019-0215-1. eCollection 2019.

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