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Items: 1 to 20 of 102


Suppressive effect of microRNA-449a on the NDRG1/PTEN/AKT axis regulates endometrial cancer growth and metastasis.

Wu AY, Hu Y, Cang W, Li D, Wang WJ, Tian Q, Gu LY, Zhang N, Ji F, Qiu LH.

Exp Cell Res. 2019 Jun 13. pii: S0014-4827(19)30308-8. doi: 10.1016/j.yexcr.2019.06.013. [Epub ahead of print]


MicroRNA-449a Inhibits Tumor Metastasis through AKT/ERK1/2 Inactivation by Targeting Steroid Receptor Coactivator (SRC) in Endometrial Cancer.

Hu Y, Wu AY, Xu C, Song KQ, Wang WJ, Yin X, Di W, Hong ZB, Qiu LH.

J Cancer. 2019 Jan 1;10(2):547-555. doi: 10.7150/jca.27748. eCollection 2019.


MiR-449a exerts tumor-suppressive functions in human glioblastoma by targeting Myc-associated zinc-finger protein.

Yao Y, Ma J, Xue Y, Wang P, Li Z, Li Z, Hu Y, Shang X, Liu Y.

Mol Oncol. 2015 Mar;9(3):640-56. doi: 10.1016/j.molonc.2014.11.003. Epub 2014 Nov 20.


MicroRNA-449a functions as a tumor suppressor in pancreatic cancer by the epigenetic regulation of ATDC expression.

Li F, Liang J, Bai L.

Biomed Pharmacother. 2018 Jul;103:782-789. doi: 10.1016/j.biopha.2018.04.101. Epub 2018 Apr 24.


MicroRNA-92a promotes epithelial-mesenchymal transition through activation of PTEN/PI3K/AKT signaling pathway in non-small cell lung cancer metastasis.

Lu C, Shan Z, Hong J, Yang L.

Int J Oncol. 2017 Jul;51(1):235-244. doi: 10.3892/ijo.2017.3999. Epub 2017 May 16.


microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest.

Zhao Z, Ma X, Sung D, Li M, Kosti A, Lin G, Chen Y, Pertsemlidis A, Hsiao TH, Du L.

RNA Biol. 2015;12(5):538-54. doi: 10.1080/15476286.2015.1023495.


MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A.

Ye W, Xue J, Zhang Q, Li F, Zhang W, Chen H, Huang Y, Zheng F.

Oncol Rep. 2014 Sep;32(3):1193-9. doi: 10.3892/or.2014.3303. Epub 2014 Jul 3.


miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1.

Liu Y, Wang Y, Sun X, Mei C, Wang L, Li Z, Zha X.

Oncotarget. 2016 Mar 22;7(12):13491-501. doi: 10.18632/oncotarget.4821.


MiR-449a suppresses cell migration and invasion by targeting PLAGL2 in breast cancer.

Xu B, Zhang X, Wang S, Shi B.

Pathol Res Pract. 2018 May;214(5):790-795. doi: 10.1016/j.prp.2017.12.012. Epub 2018 Jan 5.


The microRNA-449 family inhibits TGF-β-mediated liver cancer cell migration by targeting SOX4.

Sandbothe M, Buurman R, Reich N, Greiwe L, Vajen B, Gürlevik E, Schäffer V, Eilers M, Kühnel F, Vaquero A, Longerich T, Roessler S, Schirmacher P, Manns MP, Illig T, Schlegelberger B, Skawran B.

J Hepatol. 2017 May;66(5):1012-1021. doi: 10.1016/j.jhep.2017.01.004. Epub 2017 Jan 11.


MicroRNA-449a suppresses hepatocellular carcinoma cell growth via G1 phase arrest and the HGF/MET c-Met pathway.

Cheng J, Wu LM, Deng XS, Wu J, Lv Z, Zhao HF, Yang Z, Ni Y.

Hepatobiliary Pancreat Dis Int. 2018 Aug;17(4):336-344. doi: 10.1016/j.hbpd.2018.07.006. Epub 2018 Jul 26.


Circ-8073 regulates CEP55 by sponging miR-449a to promote caprine endometrial epithelial cells proliferation via the PI3K/AKT/mTOR pathway.

Liu X, Zhang L, Liu Y, Cui J, Che S, An X, Song Y, Cao B.

Biochim Biophys Acta Mol Cell Res. 2018 Aug;1865(8):1130-1147. doi: 10.1016/j.bbamcr.2018.05.011. Epub 2018 May 22.


MicroRNA-449a deficiency promotes colon carcinogenesis.

Niki M, Nakajima K, Ishikawa D, Nishida J, Ishifune C, Tsukumo SI, Shimada M, Nagahiro S, Mitamura Y, Yasutomo K.

Sci Rep. 2017 Sep 6;7(1):10696. doi: 10.1038/s41598-017-10500-0.


miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells.

Noonan EJ, Place RF, Basak S, Pookot D, Li LC.

Oncotarget. 2010 Sep;1(5):349-58.


Loss of miR-449a-caused PrLZ overexpression promotes prostate cancer metastasis.

Chen W, Liu Y, Chen H, Ning H, Ding K.

Int J Oncol. 2017 Aug;51(2):435-444. doi: 10.3892/ijo.2017.4038. Epub 2017 Jun 12.


MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells.

Mao A, Zhao Q, Zhou X, Sun C, Si J, Zhou R, Gan L, Zhang H.

Sci Rep. 2016 Jun 2;6:27346. doi: 10.1038/srep27346.


MicroRNA-449a inhibits proliferation and induces apoptosis by directly repressing E2F3 in gastric cancer.

Li X, Li H, Zhang R, Liu J, Liu J.

Cell Physiol Biochem. 2015;35(5):2033-42. doi: 10.1159/000374010. Epub 2015 Mar 30.


MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met.

Luo W, Huang B, Li Z, Li H, Sun L, Zhang Q, Qiu X, Wang E.

PLoS One. 2013 May 29;8(5):e64759. doi: 10.1371/journal.pone.0064759. Print 2013.


Hsa_circ_0009910 promotes carcinogenesis by promoting the expression of miR-449a target IL6R in osteosarcoma.

Deng N, Li L, Gao J, Zhou J, Wang Y, Wang C, Liu Y.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):189-196. doi: 10.1016/j.bbrc.2017.11.028. Epub 2017 Nov 5.


miR-449a Suppresses Tumor Growth, Migration, and Invasion in Non-Small Cell Lung Cancer by Targeting a HMGB1-Mediated NF-κB Signaling Pathway.

Wu D, Liu J, Chen J, He H, Ma H, Lv X.

Oncol Res. 2019 Feb 5;27(2):227-235. doi: 10.3727/096504018X15213089759999. Epub 2018 Mar 21.


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