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CXCL16/CXCR6 is involved in LPS-induced acute lung injury via P38 signalling.

Tu GW, Ju MJ, Zheng YJ, Hao GW, Ma GG, Hou JY, Zhang XP, Luo Z, Lu LM.

J Cell Mol Med. 2019 Jun 14. doi: 10.1111/jcmm.14419. [Epub ahead of print]


TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells.

Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S, Chandrasekar B.

Biochem Biophys Res Commun. 2006 Sep 8;347(4):1113-20. Epub 2006 Jul 13.


Tumor-associated macrophages promote the metastasis of ovarian carcinoma cells by enhancing CXCL16/CXCR6 expression.

Hong L, Wang S, Li W, Wu D, Chen W.

Pathol Res Pract. 2018 Sep;214(9):1345-1351. doi: 10.1016/j.prp.2018.07.009. Epub 2018 Jul 11.


Activation of the CXCL16/CXCR6 pathway promotes lipid deposition in fatty livers of apolipoprotein E knockout mice and HepG2 cells.

Ma KL, Wu Y, Zhang Y, Wang GH, Hu ZB, Ruan XZ.

Am J Transl Res. 2018 Jun 15;10(6):1802-1816. eCollection 2018.


The Role of Autophagy and the Chemokine (C-X-C Motif) Ligand 16 During Acute Lung Injury in Mice.

Gao Y, Wang N, Li RH, Xiao YZ.

Med Sci Monit. 2018 Apr 20;24:2404-2412.


Expression and regulation of the chemokine CXCL16 in Crohn's disease and models of intestinal inflammation.

Diegelmann J, Seiderer J, Niess JH, Haller D, Göke B, Reinecker HC, Brand S.

Inflamm Bowel Dis. 2010 Nov;16(11):1871-81. doi: 10.1002/ibd.21306.


Involvement of Escherichia coli in pathogenesis of xanthogranulomatous cholecystitis with scavenger receptor class A and CXCL16-CXCR6 interaction.

Sawada S, Harada K, Isse K, Sato Y, Sasaki M, Kaizaki Y, Nakanuma Y.

Pathol Int. 2007 Oct;57(10):652-63.


PDTC attenuate LPS-induced kidney injury in systemic lupus erythematosus-prone MRL/lpr mice.

Zhai JX, Zhang ZX, Feng YJ, Ding SS, Wang XH, Zou LW, Ye DQ.

Mol Biol Rep. 2012 Jun;39(6):6763-71. doi: 10.1007/s11033-012-1501-7. Epub 2012 Feb 9.


Cigarette Smoke Increases Endothelial CXCL16-Leukocyte CXCR6 Adhesion In Vitro and In Vivo. Potential Consequences in Chronic Obstructive Pulmonary Disease.

Marques P, Collado A, Escudero P, Rius C, González C, Servera E, Piqueras L, Sanz MJ.

Front Immunol. 2017 Dec 13;8:1766. doi: 10.3389/fimmu.2017.01766. eCollection 2017.


The chemokine receptor CXCR6 and its ligand CXCL16 are expressed in carcinomas and inhibit proliferation.

Meijer J, Ogink J, Kreike B, Nuyten D, de Visser KE, Roos E.

Cancer Res. 2008 Jun 15;68(12):4701-8. doi: 10.1158/0008-5472.CAN-08-0482. Retraction in: Ogink J, Kreike B, Nuyten D, de Visser KE, Roos E. Cancer Res. 2011 Feb 1;71(3):1196.


CXCL16 is activated by p-JNK and is involved in H2O2-induced HK-2 cell injury via p-ERK signaling.

Zhang W, Hua T, Li J, Zheng L, Wang Y, Xu M, Qi G.

Am J Transl Res. 2018 Nov 15;10(11):3723-3732. eCollection 2018.


Functional role of endothelial CXCL16/CXCR6-platelet-leucocyte axis in angiotensin II-associated metabolic disorders.

Collado A, Marques P, Escudero P, Rius C, Domingo E, Martinez-Hervás S, Real JT, Ascaso JF, Piqueras L, Sanz MJ.

Cardiovasc Res. 2018 Nov 1;114(13):1764-1775. doi: 10.1093/cvr/cvy135.


[Effect of pyrrolidine dithiocarbamate on oxidative stress and mitochondrial function of lung tissue in mice with acute lung injury].

Yang H, Chao K, Liang M, Sun R.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 May;30(5):428-433. doi: 10.3760/cma.j.issn.2095-4352.2018.05.007. Chinese.


Activation of the CXCL16/CXCR6 Axis by TNF-α Contributes to Ectopic Endometrial Stromal Cells Migration and Invasion.

Peng Y, Ma J, Lin J.

Reprod Sci. 2019 Mar;26(3):420-427. doi: 10.1177/1933719118776797. Epub 2018 May 20.


[Expression of CXCL16/CXCR6 in fibroblast-like synoviocytes in rheumatoid arthritis and its role in synoviocyte proliferation].

Zhang X, Zhao JX, Sun L, Liu XY.

Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Aug 18;49(4):663-668. Chinese.


CXCL16 and CXCR6 are coexpressed in human lung cancer in vivo and mediate the invasion of lung cancer cell lines in vitro.

Hu W, Liu Y, Zhou W, Si L, Ren L.

PLoS One. 2014 Jun 4;9(6):e99056. doi: 10.1371/journal.pone.0099056. eCollection 2014.


The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.

Darash-Yahana M, Gillespie JW, Hewitt SM, Chen YY, Maeda S, Stein I, Singh SP, Bedolla RB, Peled A, Troyer DA, Pikarsky E, Karin M, Farber JM.

PLoS One. 2009 Aug 19;4(8):e6695. doi: 10.1371/journal.pone.0006695.


CXCL16 upregulates RANKL expression in rheumatoid arthritis synovial fibroblasts through the JAK2/STAT3 and p38/MAPK signaling pathway.

Li CH, Xu LL, Zhao JX, Sun L, Yao ZQ, Deng XL, Liu R, Yang L, Xing R, Liu XY.

Inflamm Res. 2016 Mar;65(3):193-202. doi: 10.1007/s00011-015-0905-y. Epub 2015 Nov 30.


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