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Items: 1 to 20 of 100

1.

Curcumin induced oxidative stress attenuation by N-acetylcysteine co-treatment: a fibroblast and epithelial cell in-vitro study in idiopathic pulmonary fibrosis.

Rodriguez LR, Bui SN, Beuschel RT, Ellis E, Liberti EM, Chhina MK, Cannon B, Lemma M, Nathan SD, Grant GM.

Mol Med. 2019 Jun 13;25(1):27. doi: 10.1186/s10020-019-0096-z.

2.

Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.

Smith MR, Gangireddy SR, Narala VR, Hogaboam CM, Standiford TJ, Christensen PJ, Kondapi AK, Reddy RC.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L616-25. doi: 10.1152/ajplung.00002.2009. Epub 2010 Jan 8.

3.

Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis.

Bocchino M, Agnese S, Fagone E, Svegliati S, Grieco D, Vancheri C, Gabrielli A, Sanduzzi A, Avvedimento EV.

PLoS One. 2010 Nov 16;5(11):e14003. doi: 10.1371/journal.pone.0014003.

4.

Comparative proteome analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP) and organ donors.

Korfei M, von der Beck D, Henneke I, Markart P, Ruppert C, Mahavadi P, Ghanim B, Klepetko W, Fink L, Meiners S, Krämer OH, Seeger W, Vancheri C, Guenther A.

J Proteomics. 2013 Jun 24;85:109-28. doi: 10.1016/j.jprot.2013.04.033. Epub 2013 May 6.

5.

Differential protection of pre- versus post-treatment with curcumin, Trolox, and N-acetylcysteine against acrylonitrile-induced cytotoxicity in primary rat astrocytes.

Yu B, Changsheng Y, Wenjun Z, Ben L, Hai Q, Jing M, Guangwei X, Shuhua W, Fang L, Aschner M, Rongzhu L.

Neurotoxicology. 2015 Dec;51:58-66. doi: 10.1016/j.neuro.2015.09.011. Epub 2015 Sep 26.

PMID:
26409646
6.

Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis.

Korfei M, Stelmaszek D, MacKenzie B, Skwarna S, Chillappagari S, Bach AC, Ruppert C, Saito S, Mahavadi P, Klepetko W, Fink L, Seeger W, Lasky JA, Pullamsetti SS, Krämer OH, Guenther A.

PLoS One. 2018 Nov 27;13(11):e0207915. doi: 10.1371/journal.pone.0207915. eCollection 2018.

7.

Effect of inhaled N-acetylcysteine monotherapy on lung function and redox balance in idiopathic pulmonary fibrosis.

Muramatsu Y, Sugino K, Ishida F, Tatebe J, Morita T, Homma S.

Respir Investig. 2016 May;54(3):170-8. doi: 10.1016/j.resinv.2015.11.004. Epub 2015 Dec 30.

PMID:
27108012
8.

TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis.

Oldham JM, Ma SF, Martinez FJ, Anstrom KJ, Raghu G, Schwartz DA, Valenzi E, Witt L, Lee C, Vij R, Huang Y, Strek ME, Noth I; IPFnet Investigators.

Am J Respir Crit Care Med. 2015 Dec 15;192(12):1475-82. doi: 10.1164/rccm.201505-1010OC.

9.

N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition.

Felton VM, Borok Z, Willis BC.

Am J Physiol Lung Cell Mol Physiol. 2009 Nov;297(5):L805-12. doi: 10.1152/ajplung.00009.2009. Epub 2009 Jul 31.

10.

Oxidative/nitrosative stress, autophagy and apoptosis as therapeutic targets of melatonin in idiopathic pulmonary fibrosis.

Hosseinzadeh A, Javad-Moosavi SA, Reiter RJ, Yarahmadi R, Ghaznavi H, Mehrzadi S.

Expert Opin Ther Targets. 2018 Dec;22(12):1049-1061. doi: 10.1080/14728222.2018.1541318. Epub 2018 Nov 16. Review.

PMID:
30445883
11.

Pharmacological treatment of idiopathic pulmonary fibrosis - preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine.

Myllärniemi M, Kaarteenaho R.

Eur Clin Respir J. 2015 Feb 10;2. doi: 10.3402/ecrj.v2.26385. eCollection 2015. Review.

12.

N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycin-induced pulmonary fibrosis in rats.

Li S, Yang X, Li W, Li J, Su X, Chen L, Yan G.

Respiration. 2012;84(6):509-17. doi: 10.1159/000340041. Epub 2012 Sep 20.

13.

Effectiveness of combined therapy with pirfenidone and inhaled N-acetylcysteine for advanced idiopathic pulmonary fibrosis: a case-control study.

Sakamoto S, Muramatsu Y, Satoh K, Ishida F, Kikuchi N, Sano G, Sugino K, Isobe K, Takai Y, Homma S.

Respirology. 2015 Apr;20(3):445-52. doi: 10.1111/resp.12477. Epub 2015 Feb 2.

14.

SH2 Domain-Containing Phosphatase-2 Is a Novel Antifibrotic Regulator in Pulmonary Fibrosis.

Tzouvelekis A, Yu G, Lino Cardenas CL, Herazo-Maya JD, Wang R, Woolard T, Zhang Y, Sakamoto K, Lee H, Yi JS, DeIuliis G, Xylourgidis N, Ahangari F, Lee PJ, Aidinis V, Herzog EL, Homer R, Bennett AM, Kaminski N.

Am J Respir Crit Care Med. 2017 Feb 15;195(4):500-514. doi: 10.1164/rccm.201602-0329OC.

15.

Attenuation of bleomycin-induced lung injury and oxidative stress by N-acetylcysteine plus deferoxamine.

Teixeira KC, Soares FS, Rocha LG, Silveira PC, Silva LA, Valença SS, Dal Pizzol F, Streck EL, Pinho RA.

Pulm Pharmacol Ther. 2008;21(2):309-16. Epub 2007 Aug 29.

PMID:
17904883
16.

Desensitization of idiopathic pulmonary fibrosis fibroblasts to Alternaria alternata extract-mediated necrotic cell death.

Im J, Kim K, Yhee JY, O'Grady SM, Nho RS.

Physiol Rep. 2016 Nov;4(21). pii: e13020. Epub 2016 Nov 15.

17.

Curcumin mediates time and concentration dependent regulation of redox homeostasis leading to cytotoxicity in macrophage cells.

Kunwar A, Sandur SK, Krishna M, Priyadarsini KI.

Eur J Pharmacol. 2009 Jun 2;611(1-3):8-16. doi: 10.1016/j.ejphar.2009.03.060. Epub 2009 Apr 1.

PMID:
19344704
18.

Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits.

Rushworth GF, Megson IL.

Pharmacol Ther. 2014 Feb;141(2):150-9. doi: 10.1016/j.pharmthera.2013.09.006. Epub 2013 Sep 28. Review.

PMID:
24080471
19.

Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation.

Scharstuhl A, Mutsaers HA, Pennings SW, Szarek WA, Russel FG, Wagener FA.

J Cell Mol Med. 2009 Apr;13(4):712-25. doi: 10.1111/j.1582-4934.2008.00339.x. Epub 2008 Apr 10.

20.

R-Spondin-2 Is Upregulated in Idiopathic Pulmonary Fibrosis and Affects Fibroblast Behavior.

Munguía-Reyes A, Balderas-Martínez YI, Becerril C, Checa M, Ramírez R, Ortiz B, Meléndez-Zajgla J, Pardo A, Selman M.

Am J Respir Cell Mol Biol. 2018 Jul;59(1):65-76. doi: 10.1165/rcmb.2017-0115OC.

PMID:
29345973

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