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Items: 1 to 20 of 100

1.

Impairment of Nrf2- and Nitrergic-Mediated Gastrointestinal Motility in an MPTP Mouse Model of Parkinson's Disease.

Sampath C, Kalpana R, Ansah T, Charlton C, Hale A, Channon KM, Srinivasan S, Gangula PR.

Dig Dis Sci. 2019 Jun 11. doi: 10.1007/s10620-019-05693-5. [Epub ahead of print]

PMID:
31187328
2.

Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease.

Anderson G, Noorian AR, Taylor G, Anitha M, Bernhard D, Srinivasan S, Greene JG.

Exp Neurol. 2007 Sep;207(1):4-12. Epub 2007 May 18.

3.

Sepiapterin alleviates impaired gastric nNOS function in spontaneous diabetic female rodents through NRF2 mRNA turnover and miRNA biogenesis pathway.

Gangula PR, Challagundla KB, Ravella K, Mukhopadhyay S, Chinnathambi V, Mittal MK, Sekhar KR, Sampath C.

Am J Physiol Gastrointest Liver Physiol. 2018 Dec 1;315(6):G980-G990. doi: 10.1152/ajpgi.00152.2018. Epub 2018 Oct 4.

PMID:
30285465
4.

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

L'Episcopo F, Tirolo C, Caniglia S, Testa N, Serra PA, Impagnatiello F, Morale MC, Marchetti B.

J Neuroinflammation. 2010 Nov 23;7:83. doi: 10.1186/1742-2094-7-83.

5.

Polybacterial Periodontal Pathogens Alter Vascular and Gut BH4/nNOS/NRF2-Phase II Enzyme Expression.

Gangula P, Ravella K, Chukkapalli S, Rivera M, Srinivasan S, Hale A, Channon K, Southerland J, Kesavalu L.

PLoS One. 2015 Jun 25;10(6):e0129885. doi: 10.1371/journal.pone.0129885. eCollection 2015.

6.

Intestinal Pathology and Gut Microbiota Alterations in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Mouse Model of Parkinson's Disease.

Lai F, Jiang R, Xie W, Liu X, Tang Y, Xiao H, Gao J, Jia Y, Bai Q.

Neurochem Res. 2018 Oct;43(10):1986-1999. doi: 10.1007/s11064-018-2620-x. Epub 2018 Aug 31.

PMID:
30171422
7.

Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression.

Meng F, Wang J, Ding F, Xie Y, Zhang Y, Zhu J.

Oncol Lett. 2017 Jan;13(1):296-300. doi: 10.3892/ol.2016.5383. Epub 2016 Nov 14.

8.

Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease.

Tian YM, Chen X, Luo DZ, Zhang XH, Xue H, Zheng LF, Yang N, Wang XM, Zhu JX.

Neuroscience. 2008 May 15;153(3):634-44. doi: 10.1016/j.neuroscience.2008.02.033. Epub 2008 Feb 29.

PMID:
18420351
9.

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.

Ahuja M, Ammal Kaidery N, Yang L, Calingasan N, Smirnova N, Gaisin A, Gaisina IN, Gazaryan I, Hushpulian DM, Kaddour-Djebbar I, Bollag WB, Morgan JC, Ratan RR, Starkov AA, Beal MF, Thomas B.

J Neurosci. 2016 Jun 8;36(23):6332-51. doi: 10.1523/JNEUROSCI.0426-16.2016.

10.

Contractile dysfunction and nitrergic dysregulation in small intestine of a primate model of Parkinson's disease.

Coletto E, Dolan JS, Pritchard S, Gant A, Hikima A, Jackson MJ, Benham CD, Chaudhuri KR, Rose S, Jenner P, Iravani MM.

NPJ Parkinsons Dis. 2019 Jun 10;5:10. doi: 10.1038/s41531-019-0081-9. eCollection 2019.

11.

Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease.

Lv E, Deng J, Yu Y, Wang Y, Gong X, Jia J, Wang X.

Free Radic Res. 2015;49(11):1296-307. doi: 10.3109/10715762.2015.1067696. Epub 2015 Jul 30.

PMID:
26118717
12.

Administration of tetrahydrobiopterin restored the decline of dopamine in the striatum induced by an acute action of MPTP.

Kurosaki H, Yamaguchi K, Man-Yoshi K, Muramatsu SI, Hara S, Ichinose H.

Neurochem Int. 2019 May;125:16-24. doi: 10.1016/j.neuint.2019.02.005. Epub 2019 Feb 7.

PMID:
30739038
13.

Impairment of gastric nitrergic and NRF2 system in apolipoprotein E knockout mice.

Ravella K, Yang H, Gangula PR.

Dig Dis Sci. 2012 Jun;57(6):1504-9. doi: 10.1007/s10620-012-2070-2.

14.

GYY4137, an H2S Slow-Releasing Donor, Prevents Nitrative Stress and α-Synuclein Nitration in an MPTP Mouse Model of Parkinson's Disease.

Hou X, Yuan Y, Sheng Y, Yuan B, Wang Y, Zheng J, Liu CF, Zhang X, Hu LF.

Front Pharmacol. 2017 Oct 30;8:741. doi: 10.3389/fphar.2017.00741. eCollection 2017.

15.

Tetrahydrobiopterin (BH4), a cofactor for nNOS, restores gastric emptying and nNOS expression in female diabetic rats.

Gangula PR, Mukhopadhyay S, Ravella K, Cai S, Channon KM, Garfield RE, Pasricha PJ.

Am J Physiol Gastrointest Liver Physiol. 2010 May;298(5):G692-9. doi: 10.1152/ajpgi.00450.2009. Epub 2010 Feb 25.

16.

Neuronal nitric oxide synthase phosphorylation induced by docosahexaenoic acid protects dopaminergic neurons in an experimental model of Parkinson's disease.

Parlak H, Ozkan A, Dilmac S, Tanriover G, Ozsoy O, Agar A.

Folia Histochem Cytobiol. 2018;56(1):27-37. doi: 10.5603/FHC.a2018.0005. Epub 2018 Mar 26.

17.

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

Singh S, Singh K, Patel DK, Singh C, Nath C, Singh VK, Singh RK, Singh MP.

Rejuvenation Res. 2009 Jun;12(3):185-97. doi: 10.1089/rej.2009.0850.

PMID:
19594327
18.

Gastrodin prevents motor deficits and oxidative stress in the MPTP mouse model of Parkinson's disease: involvement of ERK1/2-Nrf2 signaling pathway.

Wang XL, Xing GH, Hong B, Li XM, Zou Y, Zhang XJ, Dong MX.

Life Sci. 2014 Oct 2;114(2):77-85. doi: 10.1016/j.lfs.2014.08.004. Epub 2014 Aug 14.

PMID:
25132361
19.

E2 and not P4 increases NO release from NANC nerves of the gastrointestinal tract: implications in pregnancy.

Shah S, Nathan L, Singh R, Fu YS, Chaudhuri G.

Am J Physiol Regul Integr Comp Physiol. 2001 May;280(5):R1546-54.

20.

MPTP-induced parkinsonism extends to a subclass of TH-positive neurons in the gut.

Natale G, Kastsiushenka O, Fulceri F, Ruggieri S, Paparelli A, Fornai F.

Brain Res. 2010 Oct 8;1355:195-206. doi: 10.1016/j.brainres.2010.07.076. Epub 2010 Aug 5.

PMID:
20691673

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