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Items: 1 to 20 of 101

1.

Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer's disease mouse model, and causes reduction of amyloid precursor protein.

Shin MK, Choi MS, Chae HJ, Kim JW, Kim HG, Kim KL.

Sci Rep. 2019 Jun 11;9(1):8512. doi: 10.1038/s41598-019-44739-6.

2.

Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.

Shin MK, Kim HG, Baek SH, Jung WR, Park DI, Park JS, Jo DG, Kim KL.

Neurobiol Aging. 2014 May;35(5):990-1001. doi: 10.1016/j.neurobiolaging.2013.10.091. Epub 2013 Oct 29.

PMID:
24268884
3.

Disease modifying effect of chronic oral treatment with a neurotrophic peptidergic compound in a triple transgenic mouse model of Alzheimer's disease.

Kazim SF, Blanchard J, Dai CL, Tung YC, LaFerla FM, Iqbal IG, Iqbal K.

Neurobiol Dis. 2014 Nov;71:110-30. doi: 10.1016/j.nbd.2014.07.001. Epub 2014 Jul 15.

PMID:
25046994
4.

The ganglioside GQ1b regulates BDNF expression via the NMDA receptor signaling pathway.

Shin MK, Jung WR, Kim HG, Roh SE, Kwak CH, Kim CH, Kim SJ, Kim KL.

Neuropharmacology. 2014 Feb;77:414-21. doi: 10.1016/j.neuropharm.2013.10.022. Epub 2013 Oct 30.

PMID:
24184316
5.

Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease.

Huang M, Jiang X, Liang Y, Liu Q, Chen S, Guo Y.

Exp Gerontol. 2017 May;91:25-33. doi: 10.1016/j.exger.2017.02.004. Epub 2017 Feb 20.

PMID:
28223223
6.

Nobiletin, a citrus flavonoid, improves cognitive impairment and reduces soluble Aβ levels in a triple transgenic mouse model of Alzheimer's disease (3XTg-AD).

Nakajima A, Aoyama Y, Shin EJ, Nam Y, Kim HC, Nagai T, Yokosuka A, Mimaki Y, Yokoi T, Ohizumi Y, Yamada K.

Behav Brain Res. 2015 Aug 1;289:69-77. doi: 10.1016/j.bbr.2015.04.028. Epub 2015 Apr 22.

PMID:
25913833
7.

Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.

Kazim SF, Chuang SC, Zhao W, Wong RK, Bianchi R, Iqbal K.

Front Aging Neurosci. 2017 Mar 24;9:71. doi: 10.3389/fnagi.2017.00071. eCollection 2017.

8.

Chronic low dose of AM404 ameliorates the cognitive impairment and pathological features in hyperglycemic 3xTg-AD mice.

Huang HJ, Chen SL, Huang HY, Sun YC, Lee GC, Lee-Chen GJ, Hsieh-Li HM, Su MT.

Psychopharmacology (Berl). 2019 Feb;236(2):763-773. doi: 10.1007/s00213-018-5108-0. Epub 2018 Nov 13.

9.

Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice.

Kapadia M, Mian MF, Michalski B, Azam AB, Ma D, Salwierz P, Christopher A, Rosa E, Zovkic IB, Forsythe P, Fahnestock M, Sakic B.

J Alzheimers Dis. 2018;63(3):1191-1205. doi: 10.3233/JAD-170779.

PMID:
29710702
10.

Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease.

Wu X, Kosaraju J, Zhou W, Tam KY.

ACS Chem Neurosci. 2017 Mar 15;8(3):676-685. doi: 10.1021/acschemneuro.6b00388. Epub 2016 Dec 29.

PMID:
28032988
11.

A novel GLP-1/GIP/Gcg triagonist reduces cognitive deficits and pathology in the 3xTg mouse model of Alzheimer's disease.

Li T, Jiao JJ, Hölscher C, Wu MN, Zhang J, Tong JQ, Dong XF, Qu XS, Cao Y, Cai HY, Su Q, Qi JS.

Hippocampus. 2018 May;28(5):358-372. doi: 10.1002/hipo.22837. Epub 2018 Mar 5.

PMID:
29473979
12.

Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms.

Giuliani D, Ottani A, Zaffe D, Galantucci M, Strinati F, Lodi R, Guarini S.

Neurobiol Learn Mem. 2013 Sep;104:82-91. doi: 10.1016/j.nlm.2013.05.006. Epub 2013 May 31.

PMID:
23726868
13.

L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.

Peng Y, Sun J, Hon S, Nylander AN, Xia W, Feng Y, Wang X, Lemere CA.

J Neurosci. 2010 Jun 16;30(24):8180-9. doi: 10.1523/JNEUROSCI.0340-10.2010.

14.

Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's disease.

Shishido H, Kishimoto Y, Kawai N, Toyota Y, Ueno M, Kubota T, Kirino Y, Tamiya T.

Neurosci Lett. 2016 Aug 26;629:62-67. doi: 10.1016/j.neulet.2016.06.066. Epub 2016 Jun 29.

PMID:
27373531
15.

Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease.

Velazquez R, Shaw DM, Caccamo A, Oddo S.

Mol Neurodegener. 2016 Jul 13;11(1):52. doi: 10.1186/s13024-016-0118-z.

16.

Sex Differences in Neuropathology and Cognitive Behavior in APP/PS1/tau Triple-Transgenic Mouse Model of Alzheimer's Disease.

Yang JT, Wang ZJ, Cai HY, Yuan L, Hu MM, Wu MN, Qi JS.

Neurosci Bull. 2018 Oct;34(5):736-746. doi: 10.1007/s12264-018-0268-9. Epub 2018 Aug 11.

PMID:
30099679
17.

Angelica tenuissima Nakai Ameliorates Cognitive Impairment and Promotes Neurogenesis in Mouse Model of Alzheimer's Disease.

Choi M, Lee Y, Cho SH.

Chin J Integr Med. 2018 May;24(5):378-384. doi: 10.1007/s11655-017-2812-2. Epub 2017 Jun 3.

PMID:
28578486
18.

Brain-derived neurotrophic factor ameliorates learning deficits in a rat model of Alzheimer's disease induced by aβ1-42.

Zhang L, Fang Y, Lian Y, Chen Y, Wu T, Zheng Y, Zong H, Sun L, Zhang R, Wang Z, Xu Y.

PLoS One. 2015 Apr 7;10(4):e0122415. doi: 10.1371/journal.pone.0122415. eCollection 2015.

19.

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.

Behav Brain Res. 2011 Sep 23;222(2):342-50. doi: 10.1016/j.bbr.2011.03.072. Epub 2011 Apr 14.

PMID:
21513747
20.

Fuzhisan ameliorates Aβ production and tau phosphorylation in hippocampal of 11month old APP/PS1 transgenic mice: A Western blot study.

Zhang ZX, Zhao RP, Wang DS, Wang AN.

Exp Gerontol. 2016 Nov;84:88-95. doi: 10.1016/j.exger.2016.09.003. Epub 2016 Sep 7.

PMID:
27612601

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