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Items: 1 to 20 of 110

1.

The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export.

Wilson MS, Jessen HJ, Saiardi A.

J Biol Chem. 2019 Jul 26;294(30):11597-11608. doi: 10.1074/jbc.RA119.007848. Epub 2019 Jun 11.

2.

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

Fridy PC, Otto JC, Dollins DE, York JD.

J Biol Chem. 2007 Oct 19;282(42):30754-62. Epub 2007 Aug 9.

3.

Deletion of inositol hexakisphosphate kinase 1 (IP6K1) reduces cell migration and invasion, conferring protection from aerodigestive tract carcinoma in mice.

Jadav RS, Kumar D, Buwa N, Ganguli S, Thampatty SR, Balasubramanian N, Bhandari R.

Cell Signal. 2016 Aug;28(8):1124-36. doi: 10.1016/j.cellsig.2016.04.011. Epub 2016 Apr 30.

4.

Inositol pyrophosphates modulate hydrogen peroxide signalling.

Onnebo SM, Saiardi A.

Biochem J. 2009 Sep 14;423(1):109-18. doi: 10.1042/BJ20090241.

PMID:
19614566
5.

Inositol hexakisphosphate kinase 1 maintains hemostasis in mice by regulating platelet polyphosphate levels.

Ghosh S, Shukla D, Suman K, Lakshmi BJ, Manorama R, Kumar S, Bhandari R.

Blood. 2013 Aug 22;122(8):1478-86. doi: 10.1182/blood-2013-01-481549. Epub 2013 Jun 19.

PMID:
23782934
6.

Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis.

Lee TS, Lee JY, Kyung JW, Yang Y, Park SJ, Lee S, Pavlovic I, Kong B, Jho YS, Jessen HJ, Kweon DH, Shin YK, Kim SH, Yoon TY, Kim S.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8314-9. doi: 10.1073/pnas.1521600113. Epub 2016 Jun 30. Erratum in: Proc Natl Acad Sci U S A. 2017 Aug 7;:.

7.

Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport.

Chanduri M, Rai A, Malla AB, Wu M, Fiedler D, Mallik R, Bhandari R.

Biochem J. 2016 Oct 1;473(19):3031-47. doi: 10.1042/BCJ20160610. Epub 2016 Jul 29.

8.

Inositol pyrophosphates: between signalling and metabolism.

Wilson MS, Livermore TM, Saiardi A.

Biochem J. 2013 Jun 15;452(3):369-79. doi: 10.1042/BJ20130118. Review.

PMID:
23725456
9.

Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase.

Fu C, Xu J, Cheng W, Rojas T, Chin AC, Snowman AM, Harraz MM, Snyder SH.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2036-2041. doi: 10.1073/pnas.1700165114. Epub 2017 Feb 2.

10.

Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity.

Lev S, Li C, Desmarini D, Saiardi A, Fewings NL, Schibeci SD, Sharma R, Sorrell TC, Djordjevic JT.

MBio. 2015 Jun 2;6(3):e00531-15. doi: 10.1128/mBio.00531-15.

11.

Eukaryotic Phosphate Homeostasis: The Inositol Pyrophosphate Perspective.

Azevedo C, Saiardi A.

Trends Biochem Sci. 2017 Mar;42(3):219-231. doi: 10.1016/j.tibs.2016.10.008. Epub 2016 Nov 19. Review.

PMID:
27876550
12.

Inositol pyrophosphate synthesis by inositol hexakisphosphate kinase 1 is required for homologous recombination repair.

Jadav RS, Chanduri MV, Sengupta S, Bhandari R.

J Biol Chem. 2013 Feb 1;288(5):3312-21. doi: 10.1074/jbc.M112.396556. Epub 2012 Dec 19.

13.

Protein kinase- and lipase inhibitors of inositide metabolism deplete IP7 indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity.

Rajasekaran SS, Illies C, Shears SB, Wang H, Ayala TS, Martins JO, Daré E, Berggren PO, Barker CJ.

Cell Signal. 2018 Jan;42:127-133. doi: 10.1016/j.cellsig.2017.10.008. Epub 2017 Oct 16.

14.

The emerging roles of inositol pyrophosphates in eukaryotic cell physiology.

Thota SG, Bhandari R.

J Biosci. 2015 Sep;40(3):593-605. Review.

15.

Inositol pyrophosphates and Akt/PKB: Is the pancreatic β-cell the exception to the rule?

Kim J, Darè E, Rajasekaran SS, Ryu SH, Berggren PO, Barker CJ.

Cell Signal. 2019 Jun;58:131-136. doi: 10.1016/j.cellsig.2019.02.003. Epub 2019 Feb 8.

16.

Analysis of Dictyostelium discoideum inositol pyrophosphate metabolism by gel electrophoresis.

Pisani F, Livermore T, Rose G, Chubb JR, Gaspari M, Saiardi A.

PLoS One. 2014 Jan 9;9(1):e85533. doi: 10.1371/journal.pone.0085533. eCollection 2014.

17.

Preparation of quality inositol pyrophosphates.

Loss O, Azevedo C, Szijgyarto Z, Bosch D, Saiardi A.

J Vis Exp. 2011 Sep 3;(55):e3027. doi: 10.3791/3027.

18.

How inositol pyrophosphates control cellular phosphate homeostasis?

Saiardi A.

Adv Biol Regul. 2012 May;52(2):351-9. doi: 10.1016/j.jbior.2012.03.002. Epub 2012 Apr 5. Review.

19.

Inositol Hexakisphosphate Kinase-2 in Cerebellar Granule Cells Regulates Purkinje Cells and Motor Coordination via Protein 4.1N.

Nagpal L, Fu C, Snyder SH.

J Neurosci. 2018 Aug 22;38(34):7409-7419. doi: 10.1523/JNEUROSCI.1165-18.2018. Epub 2018 Jul 13.

20.

Inositol Hexakisphosphate Kinase-3 Regulates the Morphology and Synapse Formation of Cerebellar Purkinje Cells via Spectrin/Adducin.

Fu C, Xu J, Li RJ, Crawford JA, Khan AB, Ma TM, Cha JY, Snowman AM, Pletnikov MV, Snyder SH.

J Neurosci. 2015 Aug 5;35(31):11056-67. doi: 10.1523/JNEUROSCI.1069-15.2015.

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