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Items: 1 to 20 of 103


Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells.

Lee J, Hong SW, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Cell Stress Chaperones. 2019 Jul;24(4):825-833. doi: 10.1007/s12192-019-01012-z. Epub 2019 Jun 10.


Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats.

Ding S, Jiang J, Zhang G, Bu Y, Zhang G, Zhao X.

PLoS One. 2017 Aug 17;12(8):e0183541. doi: 10.1371/journal.pone.0183541. eCollection 2017.


The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.

Liu LQ, Fan ZQ, Tang YF, Ke ZJ.

Alcohol Clin Exp Res. 2014 Mar;38(3):683-93. doi: 10.1111/acer.12311. Epub 2013 Nov 13.


SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism.

Guo R, Liu W, Liu B, Zhang B, Li W, Xu Y.

Int J Cardiol. 2015 Jul 15;191:36-45. doi: 10.1016/j.ijcard.2015.04.245. Epub 2015 May 1.


Exendin-4 improves ER stress-induced lipid accumulation and regulates lipin-1 signaling in HepG2 cells.

Lee J, Hong SW, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Cell Stress Chaperones. 2018 Jul;23(4):629-638. doi: 10.1007/s12192-017-0872-z. Epub 2018 Jun 22.


An ATF4-Signal-Modulating Machine Other Than GADD34 Acts in ATF4-to-CHOP Signaling to Block CHOP Expression in ER-Stress-Related Autophagy.

Iwasaki N, Sugiyama Y, Miyazaki S, Nakagawa H, Nishimura K, Matsuo S.

J Cell Biochem. 2015 Jul;116(7):1300-9. doi: 10.1002/jcb.25085.


C1q/TNF-Related Protein 9 (CTRP9) attenuates hepatic steatosis via the autophagy-mediated inhibition of endoplasmic reticulum stress.

Jung TW, Hong HC, Hwang HJ, Yoo HJ, Baik SH, Choi KM.

Mol Cell Endocrinol. 2015 Dec 5;417:131-40. doi: 10.1016/j.mce.2015.09.027. Epub 2015 Sep 28.


Endoplasmic reticulum stress in retinal vascular degeneration: protective role of resveratrol.

Li C, Wang L, Huang K, Zheng L.

Invest Ophthalmol Vis Sci. 2012 May 31;53(6):3241-9. doi: 10.1167/iovs.11-8406.


Sirt3-Mediated Autophagy Contributes to Resveratrol-Induced Protection against ER Stress in HT22 Cells.

Yan WJ, Liu RB, Wang LK, Ma YB, Ding SL, Deng F, Hu ZY, Wang DB.

Front Neurosci. 2018 Feb 27;12:116. doi: 10.3389/fnins.2018.00116. eCollection 2018.


Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1.

Ghemrawi R, Pooya S, Lorentz S, Gauchotte G, Arnold C, Gueant JL, Battaglia-Hsu SF.

Cell Death Dis. 2013 Mar 21;4:e553. doi: 10.1038/cddis.2013.69.


Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation.

Choi SI, Lee E, Akuzum B, Jeong JB, Maeng YS, Kim TI, Kim EK.

J Pineal Res. 2017 Oct;63(3). doi: 10.1111/jpi.12426. Epub 2017 Jul 18.


Hrd1 and ER-Associated Protein Degradation, ERAD, are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes.

Doroudgar S, Völkers M, Thuerauf DJ, Khan M, Mohsin S, Respress JL, Wang W, Gude N, Müller OJ, Wehrens XH, Sussman MA, Glembotski CC.

Circ Res. 2015 Aug 28;117(6):536-46. doi: 10.1161/CIRCRESAHA.115.306993. Epub 2015 Jul 2.


Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats.

Pan QR, Ren YL, Liu WX, Hu YJ, Zheng JS, Xu Y, Wang G.

Nutr Res. 2015 Jul;35(7):576-84. doi: 10.1016/j.nutres.2015.05.006. Epub 2015 May 21.


Protective Effects of Alisma orientale Extract against Hepatic Steatosis via Inhibition of Endoplasmic Reticulum Stress.

Jang MK, Han YR, Nam JS, Han CW, Kim BJ, Jeong HS, Ha KT, Jung MH.

Int J Mol Sci. 2015 Nov 2;16(11):26151-65. doi: 10.3390/ijms161125944.


Sirtuin1 and autophagy protect cells from fluoride-induced cell stress.

Suzuki M, Bartlett JD.

Biochim Biophys Acta. 2014 Feb;1842(2):245-55. doi: 10.1016/j.bbadis.2013.11.023. Epub 2013 Dec 1.


Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation.

Yoo J, Cho IJ, Jeong IK, Ahn KJ, Chung HY, Hwang YC.

Toxicol Appl Pharmacol. 2018 Dec 1;360:18-29. doi: 10.1016/j.taap.2018.09.032. Epub 2018 Sep 22.


Exendin-4 attenuates endoplasmic reticulum stress through a SIRT1-dependent mechanism.

Lee J, Hong SW, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Cell Stress Chaperones. 2014 Sep;19(5):649-56. doi: 10.1007/s12192-013-0490-3. Epub 2014 Jan 21.


SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150.

Jung TW, Lee KT, Lee MW, Ka KH.

Biochem Biophys Res Commun. 2012 Jun 1;422(2):229-32. doi: 10.1016/j.bbrc.2012.04.129. Epub 2012 Apr 30.


SIRT1/HSF1/HSP pathway is essential for exenatide-alleviated, lipid-induced hepatic endoplasmic reticulum stress.

Zheng X, Xu F, Liang H, Cao H, Cai M, Xu W, Weng J.

Hepatology. 2017 Sep;66(3):809-824. doi: 10.1002/hep.29238. Epub 2017 Jul 20.


Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver.

Li Y, Xu S, Giles A, Nakamura K, Lee JW, Hou X, Donmez G, Li J, Luo Z, Walsh K, Guarente L, Zang M.

FASEB J. 2011 May;25(5):1664-79. doi: 10.1096/fj.10-173492. Epub 2011 Feb 14.

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