Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 91


Long-term intranasal insulin aspart: a profile of gene expression, memory, and insulin receptors in aged F344 rats.

Frazier HN, Ghoweri AO, Sudkamp E, Johnson ES, Anderson KL, Fox G, Vatthanaphone K, Xia M, Lin RL, Hargis-Staggs KE, Porter NM, Pauly JR, Blalock EM, Thibault O.

J Gerontol A Biol Sci Med Sci. 2019 Jun 10. pii: glz105. doi: 10.1093/gerona/glz105. [Epub ahead of print]


Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging.

Maimaiti S, Anderson KL, DeMoll C, Brewer LD, Rauh BA, Gant JC, Blalock EM, Porter NM, Thibault O.

J Gerontol A Biol Sci Med Sci. 2016 Jan;71(1):30-9. doi: 10.1093/gerona/glu314. Epub 2015 Feb 6.


FK506-Binding Protein 12.6/1b, a Negative Regulator of [Ca2+], Rescues Memory and Restores Genomic Regulation in the Hippocampus of Aging Rats.

Gant JC, Blalock EM, Chen KC, Kadish I, Thibault O, Porter NM, Landfield PW.

J Neurosci. 2018 Jan 24;38(4):1030-1041. doi: 10.1523/JNEUROSCI.2234-17.2017. Epub 2017 Dec 18.


Intranasal insulin treatment of an experimental model of moderate traumatic brain injury.

Brabazon F, Wilson CM, Jaiswal S, Reed J, Frey WH Nd, Byrnes KR.

J Cereb Blood Flow Metab. 2017 Sep;37(9):3203-3218. doi: 10.1177/0271678X16685106. Epub 2017 Jan 6.


Broadening the definition of brain insulin resistance in aging and Alzheimer's disease.

Frazier HN, Ghoweri AO, Anderson KL, Lin RL, Porter NM, Thibault O.

Exp Neurol. 2019 Mar;313:79-87. doi: 10.1016/j.expneurol.2018.12.007. Epub 2018 Dec 18. Review.


Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains.

Adzovic L, Lynn AE, D'Angelo HM, Crockett AM, Kaercher RM, Royer SE, Hopp SC, Wenk GL.

J Neuroinflammation. 2015 Apr 2;12:63. doi: 10.1186/s12974-015-0282-z. Erratum in: J Neuroinflammation. 2015;12:142.


Insulin receptor signaling in long-term memory consolidation following spatial learning.

Dou JT, Chen M, Dufour F, Alkon DL, Zhao WQ.

Learn Mem. 2005 Nov-Dec;12(6):646-55. Epub 2005 Nov 14.


Effects of long-term pioglitazone treatment on peripheral and central markers of aging.

Blalock EM, Phelps JT, Pancani T, Searcy JL, Anderson KL, Gant JC, Popovic J, Avdiushko MG, Cohen DA, Chen KC, Porter NM, Thibault O.

PLoS One. 2010 Apr 29;5(4):e10405. doi: 10.1371/journal.pone.0010405.


Intranasal insulin improves cerebral blood flow, Nrf-2 expression and BDNF in STZ (ICV)-induced memory impaired rats.

Rajasekar N, Nath C, Hanif K, Shukla R.

Life Sci. 2017 Mar 15;173:1-10. doi: 10.1016/j.lfs.2016.09.020. Epub 2016 Sep 28.


A novel, rapidly acquired and persistent spatial memory task that induces immediate early gene expression.

Feldman LA, Shapiro ML, Nalbantoglu J.

Behav Brain Funct. 2010 Jul 2;6:35. doi: 10.1186/1744-9081-6-35.


Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory.

Vanguilder HD, Bixler GV, Sonntag WE, Freeman WM.

J Neurochem. 2012 Apr;121(1):77-98. doi: 10.1111/j.1471-4159.2012.07671.x. Epub 2012 Feb 10.


Intranasal insulin improves memory in humans: superiority of insulin aspart.

Benedict C, Hallschmid M, Schmitz K, Schultes B, Ratter F, Fehm HL, Born J, Kern W.

Neuropsychopharmacology. 2007 Jan;32(1):239-43. Epub 2006 Aug 16.


Blockade of hippocampal bradykinin B1 receptors improves spatial learning and memory deficits in middle-aged rats.

Bitencourt RM, Guerra de Souza AC, Bicca MA, Pamplona FA, de Mello N, Passos GF, Medeiros R, Takahashi RN, Calixto JB, Prediger RD.

Behav Brain Res. 2017 Jan 1;316:74-81. doi: 10.1016/j.bbr.2016.08.041. Epub 2016 Aug 24.


Intranasal insulin treatment improves memory and learning in a rat amyloid-beta model of Alzheimer's disease.

Farzampour S, Majdi A, Sadigh-Eteghad S.

Physiol Int. 2016 Sep;103(3):344-353. doi: 10.1556/2060.103.2016.3.7.


Intranasal Insulin Administration Ameliorates Streptozotocin (ICV)-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Memory Impairment in Rats.

Rajasekar N, Nath C, Hanif K, Shukla R.

Mol Neurobiol. 2017 Oct;54(8):6507-6522. doi: 10.1007/s12035-016-0169-8. Epub 2016 Oct 11.


Spatial memory impairments in a prediabetic rat model.

Soares E, Prediger RD, Nunes S, Castro AA, Viana SD, Lemos C, De Souza CM, Agostinho P, Cunha RA, Carvalho E, Fontes Ribeiro CA, Reis F, Pereira FC.

Neuroscience. 2013 Oct 10;250:565-77. doi: 10.1016/j.neuroscience.2013.07.055. Epub 2013 Jul 30.


Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment.

VanGuilder HD, Bixler GV, Brucklacher RM, Farley JA, Yan H, Warrington JP, Sonntag WE, Freeman WM.

J Neuroinflammation. 2011 Oct 11;8:138. doi: 10.1186/1742-2094-8-138.


Intranasal Insulin Prevents Anesthesia-Induced Cognitive Impairment and Chronic Neurobehavioral Changes.

Chen Y, Dai CL, Wu Z, Iqbal K, Liu F, Zhang B, Gong CX.

Front Aging Neurosci. 2017 May 10;9:136. doi: 10.3389/fnagi.2017.00136. eCollection 2017.


Differential sensitivity of men and women to anorexigenic and memory-improving effects of intranasal insulin.

Benedict C, Kern W, Schultes B, Born J, Hallschmid M.

J Clin Endocrinol Metab. 2008 Apr;93(4):1339-44. doi: 10.1210/jc.2007-2606. Epub 2008 Jan 29.


Supplemental Content

Support Center