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Items: 1 to 20 of 102


AdipoRon Attenuates Neuroinflammation After Intracerebral Hemorrhage Through AdipoR1-AMPK Pathway.

Zheng J, Sun Z, Liang F, Xu W, Lu J, Shi L, Shao A, Yu J, Zhang J.

Neuroscience. 2019 Aug 1;412:116-130. doi: 10.1016/j.neuroscience.2019.05.060. Epub 2019 Jun 7.


AdipoRon Protects Against Secondary Brain Injury After Intracerebral Hemorrhage via Alleviating Mitochondrial Dysfunction: Possible Involvement of AdipoR1-AMPK-PGC1α Pathway.

Yu J, Zheng J, Lu J, Sun Z, Wang Z, Zhang J.

Neurochem Res. 2019 Jul;44(7):1678-1689. doi: 10.1007/s11064-019-02794-5. Epub 2019 Apr 13.


Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice.

Zhao L, Chen S, Sherchan P, Ding Y, Zhao W, Guo Z, Yu J, Tang J, Zhang JH.

J Neuroinflammation. 2018 Jul 30;15(1):215. doi: 10.1186/s12974-018-1256-8.


Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice.

Chen S, Zhao L, Sherchan P, Ding Y, Yu J, Nowrangi D, Tang J, Xia Y, Zhang JH.

J Neuroinflammation. 2018 Apr 11;15(1):106. doi: 10.1186/s12974-018-1140-6.


The Adiponectin Receptor Agonist AdipoRon Ameliorates Diabetic Nephropathy in a Model of Type 2 Diabetes.

Kim Y, Lim JH, Kim MY, Kim EN, Yoon HE, Shin SJ, Choi BS, Kim YS, Chang YS, Park CW.

J Am Soc Nephrol. 2018 Apr;29(4):1108-1127. doi: 10.1681/ASN.2017060627. Epub 2018 Jan 12.


Activation of adiponectin receptors has negative impact on muscle mass in C2C12 myotubes and fast-type mouse skeletal muscle.

Ito R, Higa M, Goto A, Aoshima M, Ikuta A, Ohashi K, Yokoyama S, Ohno Y, Egawa T, Miyata H, Goto K.

PLoS One. 2018 Oct 11;13(10):e0205645. doi: 10.1371/journal.pone.0205645. eCollection 2018.


Sinomenine enhances microglia M2 polarization and attenuates inflammatory injury in intracerebral hemorrhage.

Shi H, Zheng K, Su Z, Su H, Zhong M, He X, Zhou C, Chen H, Xiong Q, Zhang Y.

J Neuroimmunol. 2016 Oct 15;299:28-34. doi: 10.1016/j.jneuroim.2016.08.010. Epub 2016 Aug 9.


Negative regulation of glial Tim-3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral hemorrhage in rats.

Chen ZQ, Yu H, Li HY, Shen HT, Li X, Zhang JY, Zhang ZW, Wang Z, Chen G.

CNS Neurosci Ther. 2019 Jun;25(6):674-684. doi: 10.1111/cns.13100. Epub 2019 Jan 24.


Regulatory T cells ameliorate intracerebral hemorrhage-induced inflammatory injury by modulating microglia/macrophage polarization through the IL-10/GSK3β/PTEN axis.

Zhou K, Zhong Q, Wang YC, Xiong XY, Meng ZY, Zhao T, Zhu WY, Liao MF, Wu LR, Yang YR, Liu J, Duan CM, Li J, Gong QW, Liu L, Yang MH, Xiong A, Wang J, Yang QW.

J Cereb Blood Flow Metab. 2017 Mar;37(3):967-979. doi: 10.1177/0271678X16648712. Epub 2016 Jul 20.


Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation.

Xu Y, Xu Y, Wang Y, Wang Y, He L, Jiang Z, Huang Z, Liao H, Li J, Saavedra JM, Zhang L, Pang T.

Brain Behav Immun. 2015 Nov;50:298-313. doi: 10.1016/j.bbi.2015.07.015. Epub 2015 Jul 16.


Minocycline promotes posthemorrhagic neurogenesis via M2 microglia polarization via upregulation of the TrkB/BDNF pathway in rats.

Miao H, Li R, Han C, Lu X, Zhang H.

J Neurophysiol. 2018 Sep 1;120(3):1307-1317. doi: 10.1152/jn.00234.2018. Epub 2018 May 23.


Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase reduces brain damage and attenuates neuroinflammation after intracerebral hemorrhage.

Wu CH, Shyue SK, Hung TH, Wen S, Lin CC, Chang CF, Chen SF.

J Neuroinflammation. 2017 Nov 25;14(1):230. doi: 10.1186/s12974-017-1005-4.


Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia.

Lan X, Han X, Li Q, Li Q, Gao Y, Cheng T, Wan J, Zhu W, Wang J.

Brain Behav Immun. 2017 Mar;61:326-339. doi: 10.1016/j.bbi.2016.12.012. Epub 2016 Dec 20.


Cannabinoid receptor-2 stimulation suppresses neuroinflammation by regulating microglial M1/M2 polarization through the cAMP/PKA pathway in an experimental GMH rat model.

Tao Y, Li L, Jiang B, Feng Z, Yang L, Tang J, Chen Q, Zhang J, Tan Q, Feng H, Chen Z, Zhu G.

Brain Behav Immun. 2016 Nov;58:118-129. doi: 10.1016/j.bbi.2016.05.020. Epub 2016 May 31.


Interleukin-33 reduces neuronal damage and white matter injury via selective microglia M2 polarization after intracerebral hemorrhage in rats.

Chen Z, Xu N, Dai X, Zhao C, Wu X, Shankar S, Huang H, Wang Z.

Brain Res Bull. 2019 Aug;150:127-135. doi: 10.1016/j.brainresbull.2019.05.016. Epub 2019 May 24.


Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells.

Ramzan AA, Bitler BG, Hicks D, Barner K, Qamar L, Behbakht K, Powell T, Jansson T, Wilson H.

Mol Cell Biochem. 2019 Jul 10. doi: 10.1007/s11010-019-03586-9. [Epub ahead of print]


Hepatoprotective effects of AdipoRon against d-galactosamine-induced liver injury in mice.

Wang Y, Wan Y, Ye G, Wang P, Xue X, Wu G, Ye B.

Eur J Pharm Sci. 2016 Oct 10;93:123-31. doi: 10.1016/j.ejps.2016.08.017. Epub 2016 Aug 9.


Administration of rCTRP9 Attenuates Neuronal Apoptosis Through AdipoR1/PI3K/Akt Signaling Pathway after ICH in Mice.

Zhao L, Zhang JH, Sherchan P, Krafft PR, Zhao W, Wang S, Chen S, Guo Z, Tang J.

Cell Transplant. 2019 Jan 14:963689718822809. doi: 10.1177/0963689718822809. [Epub ahead of print]


MiR-124 contributes to M2 polarization of microglia and confers brain inflammatory protection via the C/EBP-α pathway in intracerebral hemorrhage.

Yu A, Zhang T, Duan H, Pan Y, Zhang X, Yang G, Wang J, Deng Y, Yang Z.

Immunol Lett. 2017 Feb;182:1-11. doi: 10.1016/j.imlet.2016.12.003. Epub 2016 Dec 23.


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