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Items: 1 to 20 of 102

1.

Reversal of Osteopenia in Ovariectomized Rats by Pentoxifylline: Evidence of Osteogenic and Osteo-Angiogenic Roles of the Drug.

Pal S, Porwal K, Singh H, Malik MY, Rashid M, Kulkarni C, Khan Y, Jagavelu K, Wahajuddin M, Chattopadhyay N.

Calcif Tissue Int. 2019 Jun 7. doi: 10.1007/s00223-019-00567-4. [Epub ahead of print]

PMID:
31175387
2.

Oral dosing of pentoxifylline, a pan-phosphodiesterase inhibitor restores bone mass and quality in osteopenic rabbits by an osteogenic mechanism: A comparative study with human parathyroid hormone.

Pal S, Porwal K, Khanna K, Gautam MK, Malik MY, Rashid M, Macleod RJ, Wahajuddin M, Parameswaran V, Bellare JR, Chattopadhyay N.

Bone. 2019 Jun;123:28-38. doi: 10.1016/j.bone.2019.03.010. Epub 2019 Mar 9.

PMID:
30858147
3.

Intermittent minodronic acid treatment with sufficient bone resorption inhibition prevents reduction in bone mass and strength in ovariectomized rats with established osteopenia comparable with daily treatment.

Kimoto A, Tanaka M, Nozaki K, Mori M, Fukushima S, Mori H, Shiroya T, Nakamura T.

Bone. 2013 Jul;55(1):189-97. doi: 10.1016/j.bone.2013.02.013. Epub 2013 Feb 26.

PMID:
23486179
4.

Isoformononetin, a methoxydaidzein present in medicinal plants, reverses bone loss in osteopenic rats and exerts bone anabolic action by preventing osteoblast apoptosis.

Srivastava K, Tyagi AM, Khan K, Dixit M, Lahiri S, Kumar A, Changkija B, Khan MP, Nagar GK, Yadav DK, Maurya R, Singh SP, Jain GK, Wahajuddin, Trivedi R, Chattopadhyay N, Singh D.

Phytomedicine. 2013 Apr 15;20(6):470-80. doi: 10.1016/j.phymed.2012.12.021. Epub 2013 Feb 8.

PMID:
23395215
5.

Raloxifene and teriparatide (hPTH 1-34) have complementary effects on the osteopenic skeleton of ovariectomized rats.

Ma YL, Bryant HU, Zeng Q, Schmidt A, Jee WS, Sato M.

J Bone Miner Metab. 2005;23 Suppl:62-8.

PMID:
15984416
6.

A nutraceutical composition containing diosmin and hesperidin has osteogenic and anti-resorptive effects and expands the anabolic window of teriparatide.

Bhattacharyya S, Pal S, Mohamed R, Singh P, Chattopadhyay S, Pal China S, Porwal K, Sanyal S, Gayen JR, Chattopadhyay N.

Biomed Pharmacother. 2019 Jul 12;118:109207. doi: 10.1016/j.biopha.2019.109207. [Epub ahead of print]

PMID:
31306971
7.

Thyroid-stimulating hormone restores bone volume, microarchitecture, and strength in aged ovariectomized rats.

Sampath TK, Simic P, Sendak R, Draca N, Bowe AE, O'Brien S, Schiavi SC, McPherson JM, Vukicevic S.

J Bone Miner Res. 2007 Jun;22(6):849-59.

8.

Pharmacological activation of aldehyde dehydrogenase 2 promotes osteoblast differentiation via bone morphogenetic protein-2 and induces bone anabolic effect.

Mittal M, Pal S, China SP, Porwal K, Dev K, Shrivastava R, Raju KS, Rashid M, Trivedi AK, Sanyal S, Wahajuddin M, Bhaduria S, Maurya R, Chattopadhyay N.

Toxicol Appl Pharmacol. 2017 Feb 1;316:63-73. doi: 10.1016/j.taap.2016.12.013. Epub 2016 Dec 23.

PMID:
28017615
9.

Ulmus davidiana extract improves lumbar vertebral parameters in ovariectomized osteopenic rats.

Zhuang X, Fu C, Liu W, Wang Y, Xu F, Zhang Q, Liu Y, Liu Y.

Am J Transl Res. 2016 Feb 15;8(2):298-313. eCollection 2016.

10.

Long-term minodronic acid (ONO-5920/YM529) treatment suppresses increased bone turnover, plus prevents reduction in bone mass and bone strength in ovariectomized rats with established osteopenia.

Tanaka M, Mori H, Kayasuga R, Ochi Y, Kawada N, Yamada H, Kishikawa K.

Bone. 2008 Nov;43(5):894-900. doi: 10.1016/j.bone.2008.07.002. Epub 2008 Jul 18.

PMID:
18687415
11.

Dimethyloxalylglycine prevents bone loss in ovariectomized C57BL/6J mice through enhanced angiogenesis and osteogenesis.

Peng J, Lai ZG, Fang ZL, Xing S, Hui K, Hao C, Jin Q, Qi Z, Shen WJ, Dong QN, Bing ZH, Fu DL.

PLoS One. 2014 Nov 13;9(11):e112744. doi: 10.1371/journal.pone.0112744. eCollection 2014. Erratum in: PLoS One. 2015;10(4):e0124702.

12.

Guava fruit extract and its triterpene constituents have osteoanabolic effect: Stimulation of osteoblast differentiation by activation of mitochondrial respiration via the Wnt/β-catenin signaling.

Porwal K, Pal S, Dev K, China SP, Kumar Y, Singh C, Barbhuyan T, Sinha N, Sanyal S, Trivedi AK, Maurya R, Chattopadhyay N.

J Nutr Biochem. 2017 Jun;44:22-34. doi: 10.1016/j.jnutbio.2017.02.011. Epub 2017 Mar 8. Erratum in: J Nutr Biochem. 2017 Oct;48:138.

PMID:
28343085
13.

Enhanced osteoporotic bone regeneration by strontium-substituted calcium silicate bioactive ceramics.

Lin K, Xia L, Li H, Jiang X, Pan H, Xu Y, Lu WW, Zhang Z, Chang J.

Biomaterials. 2013 Dec;34(38):10028-42. doi: 10.1016/j.biomaterials.2013.09.056. Epub 2013 Oct 2.

PMID:
24095251
14.

Positive skeletal effects of cladrin, a naturally occurring dimethoxydaidzein, in osteopenic rats that were maintained after treatment discontinuation.

Khan K, Sharan K, Swarnkar G, Chakravarti B, Mittal M, Barbhuyan TK, China SP, Khan MP, Nagar GK, Yadav D, Dixit P, Maurya R, Chattopadhyay N.

Osteoporos Int. 2013 Apr;24(4):1455-70. doi: 10.1007/s00198-012-2121-8. Epub 2012 Aug 30.

PMID:
22932734
15.

Teriparatide [rhPTH (1-34)], but not strontium ranelate, demonstrated bone anabolic efficacy in mature, osteopenic, ovariectomized rats.

Ma YL, Zeng QQ, Porras LL, Harvey A, Moore TL, Shelbourn TL, Dalsky GP, Wronski TJ, Aguirre JI, Bryant HU, Sato M.

Endocrinology. 2011 May;152(5):1767-78. doi: 10.1210/en.2010-1112. Epub 2011 Feb 22.

PMID:
21343258
16.

A new vitamin D analog, 2MD, restores trabecular and cortical bone mass and strength in ovariectomized rats with established osteopenia.

Ke HZ, Qi H, Crawford DT, Simmons HA, Xu G, Li M, Plum L, Clagett-Dame M, DeLuca HF, Thompson DD, Brown TA.

J Bone Miner Res. 2005 Oct;20(10):1742-55. Epub 2005 Jun 13.

17.

A nonprostanoid EP4 receptor selective prostaglandin E2 agonist restores bone mass and strength in aged, ovariectomized rats.

Ke HZ, Crawford DT, Qi H, Simmons HA, Owen TA, Paralkar VM, Li M, Lu B, Grasser WA, Cameron KO, Lefker BA, DaSilva-Jardine P, Scott DO, Zhang Q, Tian XY, Jee WS, Brown TA, Thompson DD.

J Bone Miner Res. 2006 Apr;21(4):565-75. Epub 2006 Apr 5.

18.
19.

Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone.

Khedgikar V, Kushwaha P, Gautam J, Verma A, Changkija B, Kumar A, Sharma S, Nagar GK, Singh D, Trivedi PK, Sangwan NS, Mishra PR, Trivedi R.

Cell Death Dis. 2013 Aug 22;4:e778. doi: 10.1038/cddis.2013.294.

20.

Prostaglandin E2 increases bone strength in intact rats and in ovariectomized rats with established osteopenia.

Ke HZ, Shen VW, Qi H, Crawford DT, Wu DD, Liang XG, Chidsey-Frink KL, Pirie CM, Simmons HA, Thompson DD.

Bone. 1998 Sep;23(3):249-55.

PMID:
9737347

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