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Items: 1 to 20 of 93

1.

An Antitumor Bis(N-Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target.

Hu D, Yang C, Lok CN, Xing F, Lee PY, Fung YME, Jiang H, Che CM.

Angew Chem Int Ed Engl. 2019 Jun 4. doi: 10.1002/anie.201904131. [Epub ahead of print]

PMID:
31165553
2.
3.

Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.

Yu Q, Wang X, Wang L, Zheng J, Wang J, Wang B.

Scand J Gastroenterol. 2016 Oct;51(10):1220-6. doi: 10.1080/00365521.2016.1190399. Epub 2016 Jun 2.

PMID:
27251594
4.

Anti-cancer characteristics and ototoxicity of platinum(II) amine complexes with only one leaving ligand.

Monroe JD, Hruska HL, Ruggles HK, Williams KM, Smith ME.

PLoS One. 2018 Mar 7;13(3):e0192505. doi: 10.1371/journal.pone.0192505. eCollection 2018.

5.

Antitumor activity of a new platinum(II) complex with low nephrotoxicity and genotoxicity.

Marzano C, Bettio F, Baccichetti F, Trevisan A, Giovagnini L, Fregona D.

Chem Biol Interact. 2004 Jun 30;148(1-2):37-48.

PMID:
15223355
7.

Effects of histidin-2-ylidene vs. imidazol-2-ylidene ligands on the anticancer and antivascular activity of complexes of ruthenium, iridium, platinum, and gold.

Schmitt F, Donnelly K, Muenzner JK, Rehm T, Novohradsky V, Brabec V, Kasparkova J, Albrecht M, Schobert R, Mueller T.

J Inorg Biochem. 2016 Oct;163:221-228. doi: 10.1016/j.jinorgbio.2016.07.021. Epub 2016 Jul 27.

PMID:
27491634
8.

N-Heterocyclic Carbene-Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy.

Chekkat N, Dahm G, Chardon E, Wantz M, Sitz J, Decossas M, Lambert O, Frisch B, Rubbiani R, Gasser G, Guichard G, Fournel S, Bellemin-Laponnaz S.

Bioconjug Chem. 2016 Aug 17;27(8):1942-8. doi: 10.1021/acs.bioconjchem.6b00320. Epub 2016 Aug 8.

PMID:
27459208
9.
10.

Pincer-Type Platinum(II) Complexes Containing N-Heterocyclic Carbene (NHC) Ligand: Structures, Photophysical and Anion-Binding Properties, and Anticancer Activities.

Li K, Zou T, Chen Y, Guan X, Che CM.

Chemistry. 2015 May 11;21(20):7441-53. doi: 10.1002/chem.201406453. Epub 2015 Apr 1.

PMID:
25828963
11.

Organoplatinum(II) complexes containing chelating or bridging bis(N-heterocyclic carbene) ligands: formation of a platinum(II) carbonate complex by aerial CO2 fixation.

Jamali S, Milić D, Kia R, Mazloomi Z, Abdolahi H.

Dalton Trans. 2011 Oct 7;40(37):9362-5. doi: 10.1039/c1dt10736d. Epub 2011 Jun 9.

PMID:
21660338
12.

Novel cis-[(NHC)1(NHC)2(L)Cl]platinum(ii) complexes - synthesis, structures, and anticancer activities.

Rehm T, Rothemund M, Muenzner JK, Noor A, Kempe R, Schobert R.

Dalton Trans. 2016 Oct 21;45(39):15390-15398. Epub 2016 Sep 6.

PMID:
27603959
13.

The role of arsenic in the hydrolysis and DNA metalation processes in an arsenous acid-platinum(ii) anticancer complex.

Marino T, Parise A, Russo N.

Phys Chem Chem Phys. 2017 Jan 4;19(2):1328-1334. doi: 10.1039/c6cp06179f.

PMID:
27966695
14.

Water-soluble platinum nanoparticles stabilized by sulfonated N-heterocyclic carbenes: influence of the synthetic approach.

Baquero EA, Tricard S, Coppel Y, Flores JC, Chaudret B, de Jesús E.

Dalton Trans. 2018 Mar 28;47(12):4093-4104. doi: 10.1039/c8dt00240a. Epub 2018 Feb 20.

PMID:
29460941
15.

Reactivity of coordinatively unsaturated bis(N-heterocyclic carbene) Pt(II) complexes toward H(2). Crystal structure of a 14-electron Pt(II) hydride complex.

Rivada-Wheelaghan O, Roselló-Merino M, Ortuño MA, Vidossich P, Gutiérrez-Puebla E, Lledós A, Conejero S.

Inorg Chem. 2014 Apr 21;53(8):4257-68. doi: 10.1021/ic500705t. Epub 2014 Apr 9.

PMID:
24716606
17.

Imine-N-Heterocyclic Carbenes as Versatile Ligands in Ruthenium(II) p-Cymene Anticancer Complexes: A Structure-Activity Relationship Study.

Yang Y, Guo L, Tian Z, Liu X, Gong Y, Zheng H, Ge X, Liu Z.

Chem Asian J. 2018 Oct 4;13(19):2923-2933. doi: 10.1002/asia.201801058. Epub 2018 Sep 5.

PMID:
30101417
18.

Dinuclear Platinum(II) Complexes with Bone-Targeting Groups as Potential Anti-Osteosarcoma Agents.

Zhang Z, Wang X, Luo C, Zhu C, Wang K, Zhang C, Guo Z.

Chem Asian J. 2017 Jul 4;12(13):1659-1667. doi: 10.1002/asia.201700577. Epub 2017 Jun 19.

PMID:
28556606
19.
20.

Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.

Mlcouskova J, Malina J, Novohradsky V, Kasparkova J, Komeda S, Brabec V.

Biochim Biophys Acta. 2012 Oct;1820(10):1502-11. doi: 10.1016/j.bbagen.2012.05.014. Epub 2012 Jun 7.

PMID:
22683702

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