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Items: 1 to 20 of 90

1.

Lysine-specific demethylase 1 accelerates oncogenesis in p53 heterozygous mice via transcriptional repression of the residual Trp53 allele.

Wada T, Kikuchi J, Koyama D, Honda H, Furukawa Y.

Leuk Res. 2019 Jul;82:29-32. doi: 10.1016/j.leukres.2019.05.008. Epub 2019 May 23. No abstract available.

PMID:
31152920
2.

Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.

Couto SS, Cao M, Duarte PC, Banach-Petrosky W, Wang S, Romanienko P, Wu H, Cardiff RD, Abate-Shen C, Cunha GR.

Differentiation. 2009 Jan;77(1):103-11. doi: 10.1016/j.diff.2008.09.010. Epub 2008 Oct 16.

3.

Menin and p53 have non-synergistic effects on tumorigenesis in mice.

Loffler KA, Mould AW, Waring PM, Hayward NK, Kay GF.

BMC Cancer. 2012 Jun 18;12:252. doi: 10.1186/1471-2407-12-252.

5.

Metabolic activation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and DNA adduct formation depends on p53: Studies in Trp53(+/+),Trp53(+/-) and Trp53(-/-) mice.

Krais AM, Speksnijder EN, Melis JP, Singh R, Caldwell A, Gamboa da Costa G, Luijten M, Phillips DH, Arlt VM.

Int J Cancer. 2016 Feb 15;138(4):976-82. doi: 10.1002/ijc.29836. Epub 2015 Sep 22.

6.

Mutant p53 Promotes Epithelial Ovarian Cancer by Regulating Tumor Differentiation, Metastasis, and Responsiveness to Steroid Hormones.

Ren YA, Mullany LK, Liu Z, Herron AJ, Wong KK, Richards JS.

Cancer Res. 2016 Apr 15;76(8):2206-18. doi: 10.1158/0008-5472.CAN-15-1046. Epub 2016 Mar 10.

7.

Oxidative and nitrative stress caused by subcutaneous implantation of a foreign body accelerates sarcoma development in Trp53+/- mice.

Tazawa H, Tatemichi M, Sawa T, Gilibert I, Ma N, Hiraku Y, Donehower LA, Ohgaki H, Kawanishi S, Ohshima H.

Carcinogenesis. 2007 Jan;28(1):191-8. Epub 2006 Jul 20.

PMID:
16857722
8.

Identification and chromosomal assignment of two heterozygous mutations in the Trp53 gene in L5178Y/Tk(+/-)-3.7.2C mouse lymphoma cells.

Clark LS, Hart DW, Vojta PJ, Harrington-Brock K, Barrett JC, Moore MM, Tindall KR.

Mutagenesis. 1998 Sep;13(5):427-34.

PMID:
9800187
9.

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, Harris CC, Deng CX.

Nat Genet. 2001 Jul;28(3):266-71.

PMID:
11431698
10.

Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1.

Patrick NM, Griggs CA, Icenogle AL, Gilpatrick MM, Kadiyala V, Jaime-Frias R, Smith CL.

J Steroid Biochem Mol Biol. 2017 Mar;167:1-13. doi: 10.1016/j.jsbmb.2016.09.014. Epub 2016 Sep 16.

11.

The nonhomologous end joining factor Artemis suppresses multi-tissue tumor formation and prevents loss of heterozygosity.

Woo Y, Wright SM, Maas SA, Alley TL, Caddle LB, Kamdar S, Affourtit J, Foreman O, Akeson EC, Shaffer D, Bronson RT, Morse HC 3rd, Roopenian D, Mills KD.

Oncogene. 2007 Sep 6;26(41):6010-20. Epub 2007 Mar 26.

PMID:
17384673
12.
13.

Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.

Katz SF, Lechel A, Obenauf AC, Begus-Nahrmann Y, Kraus JM, Hoffmann EM, Duda J, Eshraghi P, Hartmann D, Liss B, Schirmacher P, Kestler HA, Speicher MR, Rudolph KL.

Gastroenterology. 2012 May;142(5):1229-1239.e3. doi: 10.1053/j.gastro.2012.02.009. Epub 2012 Feb 15.

PMID:
22342966
14.

KDM2B is a histone H3K79 demethylase and induces transcriptional repression via sirtuin-1-mediated chromatin silencing.

Kang JY, Kim JY, Kim KB, Park JW, Cho H, Hahm JY, Chae YC, Kim D, Kook H, Rhee S, Ha NC, Seo SB.

FASEB J. 2018 Oct;32(10):5737-5750. doi: 10.1096/fj.201800242R. Epub 2018 May 15.

PMID:
29763382
16.

The effect of Trp53 gene-dosage and parent-of-origin of inheritance on mouse gamete and embryo function in vitro.

Li A, Ganeshan L, O'Neill C.

Biol Reprod. 2012 Jun 7;86(6):175. doi: 10.1095/biolreprod.111.097741. Print 2012 Jun.

PMID:
22441798
17.

The nature of the heterozygous Trp53 knockout model for identification of mutagenic carcinogens.

French J, Storer RD, Donehower LA.

Toxicol Pathol. 2001;29 Suppl:24-9. Review.

PMID:
11695559
18.

Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice.

Hulla JE, French JE, Dunnick JK.

Carcinogenesis. 2001 Jan;22(1):89-98.

PMID:
11159746
19.

siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.

Böhringer M, Obermeier K, Griner N, Waldraff D, Dickinson E, Eirich K, Schindler D, Hagen M, Jerry DJ, Wiesmüller L.

Oncogene. 2013 Nov 28;32(48):5458-70. doi: 10.1038/onc.2013.38. Epub 2013 Feb 25.

20.

The histone demethylase lysine-specific demethylase-1-mediated epigenetic silence of KLF2 contributes to gastric cancer cell proliferation, migration, and invasion.

Fang R, Xu J, Lin H, Xu X, Tian F.

Tumour Biol. 2017 Apr;39(4):1010428317698356. doi: 10.1177/1010428317698356.

PMID:
28381185

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