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Items: 1 to 20 of 102

1.

In Vivo Exon Replacement in the Mouse Atp7b Gene by the Cas9 System.

Liu L, Cao J, Chang Q, Xing F, Yan G, Fu L, Wang H, Ma Z, Chen X, Li Y, Li S.

Hum Gene Ther. 2019 Jul 2. doi: 10.1089/hum.2019.037. [Epub ahead of print]

PMID:
31144528
2.

Generation of megabase-scale deletions, inversions and duplications involving the Contactin-6 gene in mice by CRISPR/Cas9 technology.

Korablev AN, Serova IA, Serov OL.

BMC Genet. 2017 Dec 28;18(Suppl 1):112. doi: 10.1186/s12863-017-0582-7.

3.

CRISPR/Cas9-mediated targeted T-DNA integration in rice.

Lee K, Eggenberger AL, Banakar R, McCaw ME, Zhu H, Main M, Kang M, Gelvin SB, Wang K.

Plant Mol Biol. 2019 Mar;99(4-5):317-328. doi: 10.1007/s11103-018-00819-1. Epub 2019 Jan 15.

PMID:
30645710
4.

Hot News: Gene Therapy with CRISPR/Cas9 Coming to Age for HIV Cure.

Soriano V.

AIDS Rev. 2017 Oct-Dec;19(3):167-172.

PMID:
29019352
5.

Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells.

Zheng Q, Cai X, Tan MH, Schaffert S, Arnold CP, Gong X, Chen CZ, Huang S.

Biotechniques. 2014 Sep 1;57(3):115-24. doi: 10.2144/000114196. eCollection 2014.

6.

CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.

Engelholm LH, Riaz A, Serra D, Dagnæs-Hansen F, Johansen JV, Santoni-Rugiu E, Hansen SH, Niola F, Frödin M.

Gastroenterology. 2017 Dec;153(6):1662-1673.e10. doi: 10.1053/j.gastro.2017.09.008. Epub 2017 Sep 18.

7.

Efficient generation of targeted and controlled mutational events in porcine cells using nuclease-directed homologous recombination.

Butler JR, Santos RMN, Martens GR, Ladowski JM, Wang ZY, Li P, Tector M, Tector AJ.

J Surg Res. 2017 May 15;212:238-245. doi: 10.1016/j.jss.2017.01.025. Epub 2017 Jan 29.

PMID:
28550913
8.

Targeted mutagenesis of aryl hydrocarbon receptor 2a and 2b genes in Atlantic killifish (Fundulus heteroclitus).

Aluru N, Karchner SI, Franks DG, Nacci D, Champlin D, Hahn ME.

Aquat Toxicol. 2015 Jan;158:192-201. doi: 10.1016/j.aquatox.2014.11.016. Epub 2014 Nov 26.

9.

CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments.

Boel A, De Saffel H, Steyaert W, Callewaert B, De Paepe A, Coucke PJ, Willaert A.

Dis Model Mech. 2018 Oct 18;11(10). pii: dmm035352. doi: 10.1242/dmm.035352.

10.

Postnatal Cardiac Gene Editing Using CRISPR/Cas9 With AAV9-Mediated Delivery of Short Guide RNAs Results in Mosaic Gene Disruption.

Johansen AK, Molenaar B, Versteeg D, Leitoguinho AR, Demkes C, Spanjaard B, de Ruiter H, Akbari Moqadam F, Kooijman L, Zentilin L, Giacca M, van Rooij E.

Circ Res. 2017 Oct 27;121(10):1168-1181. doi: 10.1161/CIRCRESAHA.116.310370. Epub 2017 Aug 29.

PMID:
28851809
11.

A Simple and Universal System for Gene Manipulation in Aspergillus fumigatus: In Vitro-Assembled Cas9-Guide RNA Ribonucleoproteins Coupled with Microhomology Repair Templates.

Al Abdallah Q, Ge W, Fortwendel JR.

mSphere. 2017 Nov 22;2(6). pii: e00446-17. doi: 10.1128/mSphere.00446-17. eCollection 2017 Nov-Dec.

12.

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome.

Hay EA, Khalaf AR, Marini P, Brown A, Heath K, Sheppard D, MacKenzie A.

Neuropeptides. 2017 Aug;64:101-107. doi: 10.1016/j.npep.2016.11.003. Epub 2016 Nov 4.

13.

CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani.

Zhang WW, Matlashewski G.

MBio. 2015 Jul 21;6(4):e00861. doi: 10.1128/mBio.00861-15.

14.

An Agrobacterium-delivered CRISPR/Cas9 system for high-frequency targeted mutagenesis in maize.

Char SN, Neelakandan AK, Nahampun H, Frame B, Main M, Spalding MH, Becraft PW, Meyers BC, Walbot V, Wang K, Yang B.

Plant Biotechnol J. 2017 Feb;15(2):257-268. doi: 10.1111/pbi.12611. Epub 2016 Sep 5.

15.

CRISPR/Cas9-mediated genome editing of splicing mutation causing congenital hearing loss.

Ryu N, Kim MA, Choi DG, Kim YR, Sonn JK, Lee KY, Kim UK.

Gene. 2019 Jun 30;703:83-90. doi: 10.1016/j.gene.2019.03.020. Epub 2019 Mar 18.

PMID:
30898719
16.

Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice.

Song CQ, Li Y, Mou H, Moore J, Park A, Pomyen Y, Hough S, Kennedy Z, Fischer A, Yin H, Anderson DG, Conte D Jr, Zender L, Wang XW, Thorgeirsson S, Weng Z, Xue W.

Gastroenterology. 2017 Apr;152(5):1161-1173.e1. doi: 10.1053/j.gastro.2016.12.002. Epub 2016 Dec 10.

17.

MET gene exon 14 deletion created using the CRISPR/Cas9 system enhances cellular growth and sensitivity to a MET inhibitor.

Togashi Y, Mizuuchi H, Tomida S, Terashima M, Hayashi H, Nishio K, Mitsudomi T.

Lung Cancer. 2015 Dec;90(3):590-7. doi: 10.1016/j.lungcan.2015.10.020. Epub 2015 Nov 4.

PMID:
26547802
18.

Increased efficiency of targeted mutagenesis by CRISPR/Cas9 in plants using heat stress.

LeBlanc C, Zhang F, Mendez J, Lozano Y, Chatpar K, Irish VF, Jacob Y.

Plant J. 2018 Jan;93(2):377-386. doi: 10.1111/tpj.13782. Epub 2017 Dec 22.

19.

Generation of site-specific mutant mice using the CRISPR/Cas9 system.

Bai M, Li Q, Shao YJ, Huang YH, Li DL, Ma YL.

Yi Chuan. 2015 Oct;37(10):1029-35. doi: 10.16288/j.yczz.15-127.

PMID:
26496755
20.

Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR/Cas9 Nickases.

Kocher T, Peking P, Klausegger A, Murauer EM, Hofbauer JP, Wally V, Lettner T, Hainzl S, Ablinger M, Bauer JW, Reichelt J, Koller U.

Mol Ther. 2017 Nov 1;25(11):2585-2598. doi: 10.1016/j.ymthe.2017.08.015. Epub 2017 Aug 24.

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