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Items: 1 to 20 of 90

1.

Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model.

Millecam J, van Bergen T, Schauvliege S, Antonissen G, Martens A, Chiers K, Gehring R, Gasthuys E, Vande Walle J, Croubels S, Devreese M.

Front Pharmacol. 2019 May 9;10:505. doi: 10.3389/fphar.2019.00505. eCollection 2019.

2.

In Vivo Metabolism of Ibuprofen in Growing Conventional Pigs: A Pharmacokinetic Approach.

Millecam J, De Baere S, Croubels S, Devreese M.

Front Pharmacol. 2019 Jun 27;10:712. doi: 10.3389/fphar.2019.00712. eCollection 2019.

3.

Gastrostomy tube placement via a laparotomic procedure in growing conventional piglets to perform multi-dose preclinical paediatric drug studies.

Millecam J, van Bergen T, Devreese M, Schauvliege S, Martens A, Chiers K, Croubels S, Antonissen G.

Lab Anim. 2019 Jun 26:23677219857106. doi: 10.1177/0023677219857106. [Epub ahead of print]

PMID:
31242071
4.

Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers.

Fornasini G, Monti N, Brogin G, Gallina M, Eandi M, Persiani S, Bani M, Della Pepa C, Zara G, Strolin Benedetti M.

Chirality. 1997;9(3):297-302.

PMID:
9176996
5.

Lack of effect of gender and oral contraceptive steroids on the pharmacokinetics of (R)-ibuprofen in humans.

Knights KM, McLean CF, Tonkin AL, Miners JO.

Br J Clin Pharmacol. 1995 Aug;40(2):153-6.

6.

The oral bioavailability of ibuprofen enantiomers in broiler chickens.

Vermeulen B, Remon JP.

J Vet Pharmacol Ther. 2001 Apr;24(2):105-9.

PMID:
11442784
7.
8.

Postnatal Maturation of the Glomerular Filtration Rate in Conventional Growing Piglets As Potential Juvenile Animal Model for Preclinical Pharmaceutical Research.

Gasthuys E, Devreese M, Millecam J, Sys S, Vanderperren K, Delanghe J, Vande Walle J, Heyndrickx M, Croubels S.

Front Pharmacol. 2017 Jun 29;8:431. doi: 10.3389/fphar.2017.00431. eCollection 2017.

9.

Pharmacokinetics and pharmacodynamics of enantiomers of ibuprofen and flurbiprofen after oral administration.

Suri A, Grundy BL, Derendorf H.

Int J Clin Pharmacol Ther. 1997 Jan;35(1):1-8.

PMID:
9021434
10.

Pharmacokinetics and tolerability of intravenous ibuprofen injection in healthy Chinese volunteers: a randomized, open-label, single- and multiple-dose study
.

Zhou H, Xu W, Wu G, Wu L, Shentu J, Pan Z, Hu S, Liu Y.

Int J Clin Pharmacol Ther. 2016 Nov;54(11):904-913.

PMID:
27569737
11.
12.
13.

[Plasma ibuprofen enantiomers and their pharmacokinetics in Beagle dogs determined by HPLC].

Wang HY, Kong AY, Yang B, Yan LP, Di X.

Yao Xue Xue Bao. 2015 Dec;50(12):1607-12. Chinese.

PMID:
27169284
15.

Pharmacokinetics of intravenous ibuprofen: implications of time of infusion in the treatment of pain and fever.

Smith HS, Voss B.

Drugs. 2012 Feb 12;72(3):327-37. doi: 10.2165/11599230-000000000-00000. Review.

PMID:
22316349
16.

Perioperative pharmacokinetics of ibuprofen enantiomers after rectal administration.

Kyllönen M, Olkkola KT, Seppälä T, Ryhänen P.

Paediatr Anaesth. 2005 Jul;15(7):566-73.

PMID:
15960640
17.

Rationale and conditions for the requirement of chiral bioanalytical methods in bioequivalence studies.

Torrado JJ, Blanco M, Farré M, Roset P, García-Arieta A.

Eur J Clin Pharmacol. 2010 Jun;66(6):599-604. doi: 10.1007/s00228-010-0792-7. Epub 2010 Feb 27.

PMID:
20195587
18.
19.

Population pharmacokinetic analysis of Ibuprofen enantiomers in preterm newborn infants.

Gregoire N, Desfrere L, Roze JC, Kibleur Y, Koehne P.

J Clin Pharmacol. 2008 Dec;48(12):1460-8. doi: 10.1177/0091270008323752. Epub 2008 Sep 16.

PMID:
18796580
20.

Pharmacokinetics and Bioavailability of a Fixed-Dose Combination of Ibuprofen and Paracetamol after Intravenous and Oral Administration.

Atkinson HC, Stanescu I, Frampton C, Salem II, Beasley CP, Robson R.

Clin Drug Investig. 2015 Oct;35(10):625-32. doi: 10.1007/s40261-015-0320-8.

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