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PRC2 is high maintenance.

Yu JR, Lee CH, Oksuz O, Stafford JM, Reinberg D.

Genes Dev. 2019 Aug 1;33(15-16):903-935. doi: 10.1101/gad.325050.119. Epub 2019 May 23. Review.


The Multiple Facets of PRC2 Alterations in Cancers.

Wassef M, Margueron R.

J Mol Biol. 2017 Jun 30;429(13):1978-1993. doi: 10.1016/j.jmb.2016.10.012. Epub 2016 Oct 12. Review.


Targeting EZH2 and PRC2 dependence as novel anticancer therapy.

Xu B, Konze KD, Jin J, Wang GG.

Exp Hematol. 2015 Aug;43(8):698-712. doi: 10.1016/j.exphem.2015.05.001. Epub 2015 May 28. Review.


Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer.

Laugesen A, Højfeldt JW, Helin K.

Cold Spring Harb Perspect Med. 2016 Sep 1;6(9). pii: a026575. doi: 10.1101/cshperspect.a026575. Review.


Targeting of Polycomb Repressive Complex 2 to RNA by Short Repeats of Consecutive Guanines.

Wang X, Goodrich KJ, Gooding AR, Naeem H, Archer S, Paucek RD, Youmans DT, Cech TR, Davidovich C.

Mol Cell. 2017 Mar 16;65(6):1056-1067.e5. doi: 10.1016/j.molcel.2017.02.003.


Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation.

Laugesen A, Højfeldt JW, Helin K.

Mol Cell. 2019 Apr 4;74(1):8-18. doi: 10.1016/j.molcel.2019.03.011. Review.


Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.

Son J, Shen SS, Margueron R, Reinberg D.

Genes Dev. 2013 Dec 15;27(24):2663-77. doi: 10.1101/gad.225888.113. Erratum in: Genes Dev. 2014 Apr 15;28(8):921.


Slow Chromatin Dynamics Allow Polycomb Target Genes to Filter Fluctuations in Transcription Factor Activity.

Berry S, Dean C, Howard M.

Cell Syst. 2017 Apr 26;4(4):445-457.e8. doi: 10.1016/j.cels.2017.02.013. Epub 2017 Mar 22.


Recruiting polycomb to chromatin.

van Kruijsbergen I, Hontelez S, Veenstra GJ.

Int J Biochem Cell Biol. 2015 Oct;67:177-87. doi: 10.1016/j.biocel.2015.05.006. Epub 2015 May 14. Review.


Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity.

Lavarone E, Barbieri CM, Pasini D.

Nat Commun. 2019 Apr 11;10(1):1679. doi: 10.1038/s41467-019-09624-w.


Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.

de Lucas M, Pu L, Turco G, Gaudinier A, Morao AK, Harashima H, Kim D, Ron M, Sugimoto K, Roudier F, Brady SM.

Plant Cell. 2016 Oct;28(10):2616-2631. Epub 2016 Sep 20.


Polycomb Repressor Complex 2 in Genomic Instability and Cancer.

Veneti Z, Gkouskou KK, Eliopoulos AG.

Int J Mol Sci. 2017 Jul 30;18(8). pii: E1657. doi: 10.3390/ijms18081657. Review.


Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells.

Wang Y, Long H, Yu J, Dong L, Wassef M, Zhuo B, Li X, Zhao J, Wang M, Liu C, Wen Z, Chang L, Chen P, Wang QF, Xu X, Margueron R, Li G.

BMC Biol. 2018 Sep 24;16(1):107. doi: 10.1186/s12915-018-0568-6.


Polycomb Repressive Complex 2 Methylates Elongin A to Regulate Transcription.

Ardehali MB, Anselmo A, Cochrane JC, Kundu S, Sadreyev RI, Kingston RE.

Mol Cell. 2017 Dec 7;68(5):872-884.e6. doi: 10.1016/j.molcel.2017.10.025. Epub 2017 Nov 16.


Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes.

Dozmorov MG.

Epigenetics. 2015;10(6):484-95. doi: 10.1080/15592294.2015.1040619. Epub 2015 Apr 16.


The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.

Davidovich C, Cech TR.

RNA. 2015 Dec;21(12):2007-22. doi: 10.1261/rna.053918.115. Review.


Nascent RNA interaction keeps PRC2 activity poised and in check.

Kaneko S, Son J, Bonasio R, Shen SS, Reinberg D.

Genes Dev. 2014 Sep 15;28(18):1983-8. doi: 10.1101/gad.247940.114. Epub 2014 Aug 28.


Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.

Liang SC, Hartwig B, Perera P, Mora-García S, de Leau E, Thornton H, de Lima Alves F, Rappsilber J, Yang S, James GV, Schneeberger K, Finnegan EJ, Turck F, Goodrich J.

PLoS Genet. 2015 Dec 7;11(12):e1005660. doi: 10.1371/journal.pgen.1005660. eCollection 2015 Dec. Erratum in: PLoS Genet. 2016 Feb;12(2):e1005812. de Alves, Flavia Lima [corrected to de Lima Alves, Flavia]; Rapsilber, Juri [corrected to Rappsilber, Juri].


Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing.

Moussa HF, Bsteh D, Yelagandula R, Pribitzer C, Stecher K, Bartalska K, Michetti L, Wang J, Zepeda-Martinez JA, Elling U, Stuckey JI, James LI, Frye SV, Bell O.

Nat Commun. 2019 Apr 29;10(1):1931. doi: 10.1038/s41467-019-09628-6.


Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma.

Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, Sato S, Takahashi S, Ishikawa Y, Takeuchi I, Shimogawa H, Uesugi M, Okano H, Kim SU, Wakabayashi T, Issa JP, Sekido Y, Kondo Y.

Cancer Res. 2013 Jul 15;73(14):4559-70. doi: 10.1158/0008-5472.CAN-13-0109. Epub 2013 May 29.

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