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Early recognition and treatment of neuropsychiatric symptoms to improve quality of life in early Alzheimer's disease: protocol of the BEAT-IT study.

Eikelboom WS, Singleton E, van den Berg E, Coesmans M, Mattace Raso F, van Bruchem RL, Goudzwaard JA, de Jong FJ, Koopmanschap M, den Heijer T, Driesen JJM, Vroegindeweij LJHM, Thomeer EC, Hoogers SE, Dijkstra AA, Zuidema SU, Pijnenburg YAL, Scheltens P, van Swieten JC, Ossenkoppele R, Papma JM.

Alzheimers Res Ther. 2019 May 24;11(1):48. doi: 10.1186/s13195-019-0503-2.


Screening for Cognitive Impairment in Older Adults: An Evidence Update for the U.S. Preventive Services Task Force [Internet].

Lin JS, O'Connor E, Rossom RC, Perdue LA, Burda BU, Thompson M, Eckstrom E.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Nov.


Dementia -- Caring, Ethics, Ethnical and Economical Aspects: A Systematic Review [Internet].

Swedish Council on Health Technology Assessment.

Stockholm: Swedish Council on Health Technology Assessment (SBU); 2008 Jun.


Cognitive behavioural treatment for mild Alzheimer's patients and their caregivers (CBTAC): study protocol for a randomized controlled trial.

Forstmeier S, Maercker A, Savaskan E, Roth T.

Trials. 2015 Nov 17;16:526. doi: 10.1186/s13063-015-1043-0.


Caregivers' emotional distress due to neuropsychiatric symptoms of persons with amnestic mild cognitive impairment or Alzheimer's disease.

Mavounza C, Ouellet MC, Hudon C.

Aging Ment Health. 2018 Dec 27:1-8. doi: 10.1080/13607863.2018.1544208. [Epub ahead of print]


Goal-oriented cognitive rehabilitation for early-stage Alzheimer's and related dementias: the GREAT RCT.

Clare L, Kudlicka A, Oyebode JR, Jones RW, Bayer A, Leroi I, Kopelman M, James IA, Culverwell A, Pool J, Brand A, Henderson C, Hoare Z, Knapp M, Morgan-Trimmer S, Burns A, Corbett A, Whitaker R, Woods B.

Health Technol Assess. 2019 Mar;23(10):1-242. doi: 10.3310/hta23100.


Emotion Detection Deficits and Decreased Empathy in Patients with Alzheimer's Disease and Parkinson's Disease Affect Caregiver Mood and Burden.

Martinez M, Multani N, Anor CJ, Misquitta K, Tang-Wai DF, Keren R, Fox S, Lang AE, Marras C, Tartaglia MC.

Front Aging Neurosci. 2018 Apr 24;10:120. doi: 10.3389/fnagi.2018.00120. eCollection 2018.


Caregiver- and patient-directed interventions for dementia: an evidence-based analysis.

Medical Advisory Secretariat.

Ont Health Technol Assess Ser. 2008;8(4):1-98. Epub 2008 Oct 1.


Frequency and subgroups of neuropsychiatric symptoms in mild cognitive impairment and different stages of dementia in Alzheimer's disease.

Siafarikas N, Selbaek G, Fladby T, Šaltytė Benth J, Auning E, Aarsland D.

Int Psychogeriatr. 2018 Jan;30(1):103-113. doi: 10.1017/S1041610217001879. Epub 2017 Sep 20.


Quality of Life in relation to neuropsychiatric symptoms in Alzheimer's disease: 5-year prospective ALSOVA cohort study.

Hongisto K, Hallikainen I, Selander T, Törmälehto S, Väätäinen S, Martikainen J, Välimäki T, Hartikainen S, Suhonen J, Koivisto AM.

Int J Geriatr Psychiatry. 2018 Jan;33(1):47-57. doi: 10.1002/gps.4666. Epub 2017 Jan 9.


The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomised controlled trial.

Orrell M, Yates L, Leung P, Kang S, Hoare Z, Whitaker C, Burns A, Knapp M, Leroi I, Moniz-Cook E, Pearson S, Simpson S, Spector A, Roberts S, Russell I, de Waal H, Woods RT, Orgeta V.

PLoS Med. 2017 Mar 28;14(3):e1002269. doi: 10.1371/journal.pmed.1002269. eCollection 2017 Mar.


Neuropsychiatric symptoms as the main determinant of caregiver burden in Alzheimer's disease.

Kochhann R, Borba E, Cerveira MO, Onyszko D, de Jesus A, Forster L, Franciscatto L, Godinho C, Camozzato AL, Chaves MLF.

Dement Neuropsychol. 2011 Jul-Sep;5(3):203-208. doi: 10.1590/S1980-57642011DN05030008.


Behavioural interventions for urinary incontinence in community-dwelling seniors: an evidence-based analysis.

Medical Advisory Secretariat.

Ont Health Technol Assess Ser. 2008;8(3):1-52. Epub 2008 Oct 1.


The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy: study protocol for a randomized controlled trial.

Chiatti C, Masera F, Rimland JM, Cherubini A, Scarpino O, Spazzafumo L, Lattanzio F; UP-TECH research group.

Trials. 2013 May 28;14:155. doi: 10.1186/1745-6215-14-155.


Effect of second-generation antipsychotics on caregiver burden in Alzheimer's disease.

Mohamed S, Rosenheck R, Lyketsos CG, Kaczynski R, Sultzer DL, Schneider LS.

J Clin Psychiatry. 2012 Jan;73(1):121-8. doi: 10.4088/JCP.10m06574. Epub 2011 Sep 6.


Neuropsychiatric symptoms in Alzheimer's disease: associations with caregiver burden and treatment outcomes.

Chen CT, Chang CC, Chang WN, Tsai NW, Huang CC, Chang YT, Wang HC, Kung CT, Su YJ, Lin WC, Cheng BC, Su CM, Hsiao SY, Hsu CW, Lu CH.

QJM. 2017 Sep 1;110(9):565-570. doi: 10.1093/qjmed/hcx077.


A three-year follow-up on the efficacy of psychosocial interventions for patients with mild dementia and their caregivers: the multicentre, rater-blinded, randomised Danish Alzheimer Intervention Study (DAISY).

Phung KT, Waldorff FB, Buss DV, Eckermann A, Keiding N, Rishøj S, Siersma V, Sørensen J, Søgaard R, Sørensen LV, Vogel A, Waldemar G.

BMJ Open. 2013 Nov 21;3(11):e003584. doi: 10.1136/bmjopen-2013-003584.


TIME - Targeted interdisciplinary model for evaluation and treatment of neuropsychiatric symptoms: protocol for an effectiveness-implementation cluster randomized hybrid trial.

Lichtwarck B, Selbaek G, Kirkevold Ø, Rokstad AM, Benth JŠ, Myhre J, Nybakken S, Bergh S.

BMC Psychiatry. 2016 Jul 12;16:233. doi: 10.1186/s12888-016-0944-0.


The Progression of Neuropsychiatric Symptoms in Alzheimer's Disease During a Five-Year Follow-Up: Kuopio ALSOVA Study.

Hallikainen I, Hongisto K, Välimäki T, Hänninen T, Martikainen J, Koivisto AM.

J Alzheimers Dis. 2018;61(4):1367-1376. doi: 10.3233/JAD-170697.


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