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Items: 1 to 20 of 98

1.

Highly Stable, Coordinated Polymeric Nanoparticles Loading Copper(II) Diethyldithiocarbamate for Combinational Chemo/Chemodynamic Therapy of Cancer.

Peng X, Pan Q, Zhang B, Wan S, Li S, Luo K, Pu Y, He B.

Biomacromolecules. 2019 Jun 10;20(6):2372-2383. doi: 10.1021/acs.biomac.9b00367. Epub 2019 May 30.

PMID:
31117352
2.

Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers.

Chen W, Yang W, Chen P, Huang Y, Li F.

ACS Appl Mater Interfaces. 2018 Dec 5;10(48):41118-41128. doi: 10.1021/acsami.8b14940. Epub 2018 Nov 16.

PMID:
30444340
3.

Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent.

Wehbe M, Anantha M, Shi M, Leung AW, Dragowska WH, Sanche L, Bally MB.

Int J Nanomedicine. 2017 May 31;12:4129-4146. doi: 10.2147/IJN.S137347. eCollection 2017.

4.

Hydroxycobalamin catalyzes the oxidation of diethyldithiocarbamate and increases its cytotoxicity independently of copper ions.

Solovieva ME, Shatalin YV, Solovyev VV, Sazonov AV, Kutyshenko VP, Akatov VS.

Redox Biol. 2019 Jan;20:28-37. doi: 10.1016/j.redox.2018.09.016. Epub 2018 Sep 25.

5.

A binuclear complex constituted by diethyldithiocarbamate and copper(I) functions as a proteasome activity inhibitor in pancreatic cancer cultures and xenografts.

Han J, Liu L, Yue X, Chang J, Shi W, Hua Y.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):477-83. doi: 10.1016/j.taap.2013.09.009. Epub 2013 Sep 20.

6.

Synergistic breast tumor cell killing achieved by intracellular co-delivery of doxorubicin and disulfiram via core-shell-corona nanoparticles.

Tao X, Gou J, Zhang Q, Tan X, Ren T, Yao Q, Tian B, Kou L, Zhang L, Tang X.

Biomater Sci. 2018 Jun 25;6(7):1869-1881. doi: 10.1039/c8bm00271a.

PMID:
29808221
7.

Stable loading and delivery of disulfiram with mPEG-PLGA/PCL mixed nanoparticles for tumor therapy.

Song W, Tang Z, Lei T, Wen X, Wang G, Zhang D, Deng M, Tang X, Chen X.

Nanomedicine. 2016 Feb;12(2):377-86. doi: 10.1016/j.nano.2015.10.022. Epub 2015 Dec 19.

PMID:
26711966
8.

Development and characterisation of disulfiram-loaded PLGA nanoparticles for the treatment of non-small cell lung cancer.

Najlah M, Ahmed Z, Iqbal M, Wang Z, Tawari P, Wang W, McConville C.

Eur J Pharm Biopharm. 2017 Mar;112:224-233. doi: 10.1016/j.ejpb.2016.11.032. Epub 2016 Nov 30.

PMID:
27915005
9.
10.

Enhanced Tumor-Specific Disulfiram Chemotherapy by In Situ Cu2+ Chelation-Initiated Nontoxicity-to-Toxicity Transition.

Wu W, Yu L, Jiang Q, Huo M, Lin H, Wang L, Chen Y, Shi J.

J Am Chem Soc. 2019 Jul 15. doi: 10.1021/jacs.9b03503. [Epub ahead of print]

PMID:
31251050
11.

Suppressing autophagy enhances disulfiram/copper-induced apoptosis in non-small cell lung cancer.

Wu X, Xue X, Wang L, Wang W, Han J, Sun X, Zhang H, Liu Y, Che X, Yang J, Wu C.

Eur J Pharmacol. 2018 May 15;827:1-12. doi: 10.1016/j.ejphar.2018.02.039. Epub 2018 Mar 13.

PMID:
29547841
12.

A multifunctional ternary Cu(II)-carboxylate coordination polymeric nanocomplex for cancer thermochemotherapy.

Zhang C, Li J, Qian C, Luo X, Wang K, Zhao P, Sun M.

Int J Pharm. 2018 Oct 5;549(1-2):1-12. doi: 10.1016/j.ijpharm.2018.06.048. Epub 2018 Jul 2.

PMID:
30057350
13.

Reactions of bovine serum amine oxidase with NN-diethyldithiocarbamate. Selective removal of one copper ion.

Morpurgo L, Agostinelli E, Befani O, Mondovì B.

Biochem J. 1987 Dec 15;248(3):865-70.

14.

Targeting ALDH2 with disulfiram/copper reverses the resistance of cancer cells to microtubule inhibitors.

Wang NN, Wang LH, Li Y, Fu SY, Xue X, Jia LN, Yuan XZ, Wang YT, Tang X, Yang JY, Wu CF.

Exp Cell Res. 2018 Jan 1;362(1):72-82. doi: 10.1016/j.yexcr.2017.11.004. Epub 2017 Nov 16.

PMID:
29155365
15.

A nanoparticle formulation of disulfiram prolongs corneal residence time of the drug and reduces intraocular pressure.

Nagai N, Yoshioka C, Mano Y, Tnabe W, Ito Y, Okamoto N, Shimomura Y.

Exp Eye Res. 2015 Mar;132:115-23. doi: 10.1016/j.exer.2015.01.022. Epub 2015 Jan 26.

PMID:
25633346
16.

Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status.

Wehbe M, Lo C, Leung AWY, Dragowska WH, Ryan GM, Bally MB.

Invest New Drugs. 2017 Dec;35(6):682-690. doi: 10.1007/s10637-017-0488-2. Epub 2017 Jul 21.

17.

Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate-copper complex loaded into hyaluronic acid decorated liposomes.

Marengo A, Forciniti S, Dando I, Dalla Pozza E, Stella B, Tsapis N, Yagoubi N, Fanelli G, Fattal E, Heeschen C, Palmieri M, Arpicco S.

Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):61-72. doi: 10.1016/j.bbagen.2018.09.018. Epub 2018 Sep 26.

PMID:
30267751
18.

Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways.

Li Y, Wang LH, Zhang HT, Wang YT, Liu S, Zhou WL, Yuan XZ, Li TY, Wu CF, Yang JY.

J Cell Mol Med. 2018 Jan;22(1):439-451. doi: 10.1111/jcmm.13334. Epub 2017 Nov 17.

19.

Anticancer drug-loaded nanospheres based on biodegradable amphiphilic ε-caprolactone and carbonate copolymers.

Yan GP, Zong RF, Li L, Fu T, Liu F, Yu XH.

Pharm Res. 2010 Dec;27(12):2743-52. doi: 10.1007/s11095-010-0275-7. Epub 2010 Sep 22.

PMID:
20859660
20.

Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells.

Liu X, Wang L, Cui W, Yuan X, Lin L, Cao Q, Wang N, Li Y, Guo W, Zhang X, Wu C, Yang J.

Oncotarget. 2016 Sep 6;7(36):58516-58530. doi: 10.18632/oncotarget.11305.

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