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Items: 1 to 20 of 101

1.

Mutational landscape in genetically engineered, carcinogen-induced, and radiation-induced mouse sarcoma.

Lee CL, Mowery YM, Daniel AR, Zhang D, Sibley AB, Delaney JR, Wisdom AJ, Qin X, Wang X, Caraballo I, Gresham J, Luo L, Van Mater D, Owzar K, Kirsch DG.

JCI Insight. 2019 Jul 11;4(13). pii: 128698. doi: 10.1172/jci.insight.128698.

2.

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.

McFadden DG, Politi K, Bhutkar A, Chen FK, Song X, Pirun M, Santiago PM, Kim-Kiselak C, Platt JT, Lee E, Hodges E, Rosebrock AP, Bronson RT, Socci ND, Hannon GJ, Jacks T, Varmus H.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6409-E6417. Epub 2016 Oct 4.

3.

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.

Westcott PM, Halliwill KD, To MD, Rashid M, Rust AG, Keane TM, Delrosario R, Jen KY, Gurley KE, Kemp CJ, Fredlund E, Quigley DA, Adams DJ, Balmain A.

Nature. 2015 Jan 22;517(7535):489-92. doi: 10.1038/nature13898. Epub 2014 Nov 2.

4.

Analysis of the c-myc, K-ras and p53 genes in methylcholanthrene-induced mouse sarcomas.

Watanabe H, Shimokado K, Asahara T, Dohi K, Niwa O.

Jpn J Cancer Res. 1999 Jan;90(1):40-7.

5.

Genomic and transcriptomic comparison of post-radiation versus sporadic sarcomas.

Lesluyes T, Baud J, Pérot G, Charon-Barra C, You A, Valo I, Bazille C, Mishellany F, Leroux A, Renard-Oldrini S, Terrier P, Le Cesne A, Laé M, Piperno-Neumann S, Bonvalot S, Neuville A, Collin F, Maingon P, Coindre JM, Chibon F.

Mod Pathol. 2019 Jun 26. doi: 10.1038/s41379-019-0300-2. [Epub ahead of print]

PMID:
31243333
6.

Injury promotes sarcoma development in a genetically and temporally restricted manner.

Van Mater D, Xu E, Reddy A, Añó L, Sachdeva M, Huang W, Williams N, Ma Y, Love C, Happ L, Dave S, Kirsch DG.

JCI Insight. 2018 Oct 18;3(20). pii: 123687. doi: 10.1172/jci.insight.123687.

7.

Targeted next-generation sequencing of CIC-DUX4 soft tissue sarcomas demonstrates low mutational burden and recurrent chromosome 1p loss.

Lazo de la Vega L, Hovelson DH, Cani AK, Liu CJ, McHugh JB, Lucas DR, Thomas DG, Patel RM, Tomlins SA.

Hum Pathol. 2016 Dec;58:161-170. doi: 10.1016/j.humpath.2016.09.004. Epub 2016 Sep 21.

8.

Atypical fibroxanthoma and pleomorphic dermal sarcoma harbor frequent NOTCH1/2 and FAT1 mutations and similar DNA copy number alteration profiles.

Griewank KG, Wiesner T, Murali R, Pischler C, Müller H, Koelsche C, Möller I, Franklin C, Cosgarea I, Sucker A, Schadendorf D, Schaller J, Horn S, Brenn T, Mentzel T.

Mod Pathol. 2018 Mar;31(3):418-428. doi: 10.1038/modpathol.2017.146. Epub 2017 Nov 3.

9.

Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma.

Cheng L, Pandya PH, Liu E, Chandra P, Wang L, Murray ME, Carter J, Ferguson M, Saadatzadeh MR, Bijangi-Visheshsaraei K, Marshall M, Li L, Pollok KE, Renbarger JL.

BMC Med Genomics. 2019 Jan 31;12(Suppl 1):23. doi: 10.1186/s12920-018-0456-5.

10.

Analysis of 7,815 cancer exomes reveals associations between mutational processes and somatic driver mutations.

Poulos RC, Wong YT, Ryan R, Pang H, Wong JWH.

PLoS Genet. 2018 Nov 9;14(11):e1007779. doi: 10.1371/journal.pgen.1007779. eCollection 2018 Nov.

11.

Mutational analysis of PIK3CA, JAK2, BRAF, FOXL2, IDH1, AKT1 and EZH2 oncogenes in sarcomas.

Je EM, An CH, Yoo NJ, Lee SH.

APMIS. 2012 Aug;120(8):635-9. doi: 10.1111/j.1600-0463.2012.02878.x. Epub 2012 Mar 24.

PMID:
22779686
12.

Whole exome sequencing-based analysis to identify DNA damage repair deficiency as a major contributor to gliomagenesis in adult diffuse gliomas.

Ülgen E, Can Ö, Bilguvar K, Oktay Y, Akyerli CB, Danyeli AE, Yakıcıer MC, Sezerman OU, Pamir MN, Özduman K.

J Neurosurg. 2019 Apr 5:1-12. doi: 10.3171/2019.1.JNS182938. [Epub ahead of print]

PMID:
30952131
13.

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models.

Yen J, White RM, Wedge DC, Van Loo P, de Ridder J, Capper A, Richardson J, Jones D, Raine K, Watson IR, Wu CJ, Cheng J, Martincorena I, Nik-Zainal S, Mudie L, Moreau Y, Marshall J, Ramakrishna M, Tarpey P, Shlien A, Whitmore I, Gamble S, Latimer C, Langdon E, Kaufman C, Dovey M, Taylor A, Menzies A, McLaren S, O'Meara S, Butler A, Teague J, Lister J, Chin L, Campbell P, Adams DJ, Zon LI, Patton EE, Stemple DL, Futreal PA.

Genome Biol. 2013;14(10):R113.

14.

Association of minisatellite instability with c-myc amplification and K-ras mutation in methylcholanthrene-induced mouse sarcomas.

Niwa O, Kamiya K, Furihata C, Nitta Y, Wang Z, Fan YJ, Ninomiya Y, Kotomura N, Numoto M, Kominami R.

Cancer Res. 1995 Dec 1;55(23):5670-6.

15.

Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics.

Pérot G, Chibon F, Montero A, Lagarde P, de Thé H, Terrier P, Guillou L, Ranchère D, Coindre JM, Aurias A.

Am J Pathol. 2010 Oct;177(4):2080-90. doi: 10.2353/ajpath.2010.100104.

16.

Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma.

Nassar D, Latil M, Boeckx B, Lambrechts D, Blanpain C.

Nat Med. 2015 Aug;21(8):946-54. doi: 10.1038/nm.3878. Epub 2015 Jul 13. Erratum in: Nat Med. 2016 Feb;22(2):217.

PMID:
26168291
17.

Mutational landscape of a chemically-induced mouse model of liver cancer.

Connor F, Rayner TF, Aitken SJ, Feig C, Lukk M, Santoyo-Lopez J, Odom DT.

J Hepatol. 2018 Oct;69(4):840-850. doi: 10.1016/j.jhep.2018.06.009. Epub 2018 Jun 26.

18.

Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.

Sawada G, Niida A, Uchi R, Hirata H, Shimamura T, Suzuki Y, Shiraishi Y, Chiba K, Imoto S, Takahashi Y, Iwaya T, Sudo T, Hayashi T, Takai H, Kawasaki Y, Matsukawa T, Eguchi H, Sugimachi K, Tanaka F, Suzuki H, Yamamoto K, Ishii H, Shimizu M, Yamazaki H, Yamazaki M, Tachimori Y, Kajiyama Y, Natsugoe S, Fujita H, Mafune K, Tanaka Y, Kelsell DP, Scott CA, Tsuji S, Yachida S, Shibata T, Sugano S, Doki Y, Akiyama T, Aburatani H, Ogawa S, Miyano S, Mori M, Mimori K.

Gastroenterology. 2016 May;150(5):1171-1182. doi: 10.1053/j.gastro.2016.01.035. Epub 2016 Feb 10.

19.

Case Report: Exome sequencing reveals recurrent RETSAT mutations and a loss-of-function POLDIP2 mutation in a rare undifferentiated tongue sarcoma.

Chan JYK, Poon PHY, Zhang Y, Ng CWK, Piao WY, Ma M, Yip KY, Chan ABW, Lui VWY.

F1000Res. 2018 Apr 26;7:499. doi: 10.12688/f1000research.14383.1. eCollection 2018.

20.

Mutational Analysis of Ionizing Radiation Induced Neoplasms.

Sherborne AL, Davidson PR, Yu K, Nakamura AO, Rashid M, Nakamura JL.

Cell Rep. 2015 Sep 22;12(11):1915-26. doi: 10.1016/j.celrep.2015.08.015. Epub 2015 Sep 3.

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