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Role of B7H3/IL-33 Signaling in Pulmonary Fibrosis-induced Profibrogenic Alterations in Bone Marrow.

Nakashima T, Liu T, Hu B, Wu Z, Ullenbruch M, Omori K, Ding L, Hattori N, Phan SH.

Am J Respir Crit Care Med. 2019 Oct 15;200(8):1032-1044. doi: 10.1164/rccm.201808-1560OC.


An ST2-dependent role of bone marrow-derived group 2 innate lymphoid cells in pulmonary fibrosis.

Zhao Y, De Los Santos FG, Wu Z, Liu T, Phan SH.

J Pathol. 2018 Aug;245(4):399-409. doi: 10.1002/path.5092. Epub 2018 Jun 5.


Lung bone marrow-derived hematopoietic progenitor cells enhance pulmonary fibrosis.

Nakashima T, Liu T, Yu H, Ding L, Ullenbruch M, Hu B, Wu Z, Oguro H, Phan SH.

Am J Respir Crit Care Med. 2013 Oct 15;188(8):976-84. doi: 10.1164/rccm.201303-0479OC.


IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice.

Li D, Guabiraba R, Besnard AG, Komai-Koma M, Jabir MS, Zhang L, Graham GJ, Kurowska-Stolarska M, Liew FY, McSharry C, Xu D.

J Allergy Clin Immunol. 2014 Dec;134(6):1422-1432.e11. doi: 10.1016/j.jaci.2014.05.011. Epub 2014 Jun 27.


Characterization of lung stem cell niches in a mouse model of bleomycin-induced fibrosis.

Banerjee ER, Henderson WR Jr.

Stem Cell Res Ther. 2012 May 29;3(3):21. doi: 10.1186/scrt112.


NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis.

Li X, Li C, Tang Y, Huang Y, Cheng Q, Huang X, Zhao F, Hao C, Feng D, Xu J, Han J, Tang S, Liu W, Yue S, Luo Z.

Am J Physiol Lung Cell Mol Physiol. 2018 Sep 1;315(3):L404-L421. doi: 10.1152/ajplung.00002.2018. Epub 2018 May 3.


Telomerase activity is required for bleomycin-induced pulmonary fibrosis in mice.

Liu T, Chung MJ, Ullenbruch M, Yu H, Jin H, Hu B, Choi YY, Ishikawa F, Phan SH.

J Clin Invest. 2007 Dec;117(12):3800-9.


Inhibition of Wnt/β-catenin signaling promotes epithelial differentiation of mesenchymal stem cells and repairs bleomycin-induced lung injury.

Wang C, Zhu H, Sun Z, Xiang Z, Ge Y, Ni C, Luo Z, Qian W, Han X.

Am J Physiol Cell Physiol. 2014 Aug 1;307(3):C234-44. doi: 10.1152/ajpcell.00366.2013. Epub 2014 Jun 4.


Prominin-1/CD133+ lung epithelial progenitors protect from bleomycin-induced pulmonary fibrosis.

Germano D, Blyszczuk P, Valaperti A, Kania G, Dirnhofer S, Landmesser U, Lüscher TF, Hunziker L, Zulewski H, Eriksson U.

Am J Respir Crit Care Med. 2009 May 15;179(10):939-49. doi: 10.1164/rccm.200809-1390OC. Epub 2009 Feb 20.


Paired immunoglobulin-like receptor-B inhibits pulmonary fibrosis by suppressing profibrogenic properties of alveolar macrophages.

Karo-Atar D, Moshkovits I, Eickelberg O, Königshoff M, Munitz A.

Am J Respir Cell Mol Biol. 2013 Apr;48(4):456-64. doi: 10.1165/rcmb.2012-0329OC.


Cyclophosphamide Combined with Bone Marrow Mesenchymal Stromal Cells Protects against Bleomycin-induced Lung Fibrosis in Mice.

Xu J, Li L, Xiong J, Zheng Y, Ye Q, Li Y.

Ann Clin Lab Sci. 2015 Spring;45(3):292-300.


Discoidin domain receptor 1-deficient mice are resistant to bleomycin-induced lung fibrosis.

Avivi-Green C, Singal M, Vogel WF.

Am J Respir Crit Care Med. 2006 Aug 15;174(4):420-7. Epub 2006 May 11.


The in vivo fibrotic role of FIZZ1 in pulmonary fibrosis.

Liu T, Yu H, Ullenbruch M, Jin H, Ito T, Wu Z, Liu J, Phan SH.

PLoS One. 2014 Feb 6;9(2):e88362. doi: 10.1371/journal.pone.0088362. eCollection 2014.


Tissue inhibitor of metalloproteinase-1 deficiency amplifies acute lung injury in bleomycin-exposed mice.

Kim KH, Burkhart K, Chen P, Frevert CW, Randolph-Habecker J, Hackman RC, Soloway PD, Madtes DK.

Am J Respir Cell Mol Biol. 2005 Sep;33(3):271-9. Epub 2005 Jun 9.


Repetitive intradermal bleomycin injections evoke T-helper cell 2 cytokine-driven pulmonary fibrosis.

Singh B, Kasam RK, Sontake V, Wynn TA, Madala SK.

Am J Physiol Lung Cell Mol Physiol. 2017 Nov 1;313(5):L796-L806. doi: 10.1152/ajplung.00184.2017. Epub 2017 Aug 3.


IRAK-M promotes alternative macrophage activation and fibroproliferation in bleomycin-induced lung injury.

Ballinger MN, Newstead MW, Zeng X, Bhan U, Mo XM, Kunkel SL, Moore BB, Flavell R, Christman JW, Standiford TJ.

J Immunol. 2015 Feb 15;194(4):1894-904. doi: 10.4049/jimmunol.1402377. Epub 2015 Jan 16.


Sphingosine-1-phosphate receptor-2 facilitates pulmonary fibrosis through potentiating IL-13 pathway in macrophages.

Zhao J, Okamoto Y, Asano Y, Ishimaru K, Aki S, Yoshioka K, Takuwa N, Wada T, Inagaki Y, Takahashi C, Nishiuchi T, Takuwa Y.

PLoS One. 2018 May 21;13(5):e0197604. doi: 10.1371/journal.pone.0197604. eCollection 2018.


Follistatin-Like 1 Promotes Bleomycin-Induced Pulmonary Fibrosis through the Transforming Growth Factor Beta 1/Mitogen-Activated Protein Kinase Signaling Pathway.

Jin YK, Li XH, Wang W, Liu J, Zhang W, Fang YS, Zhang ZF, Dai HP, Ning W, Wang C.

Chin Med J (Engl). 2018 Aug 20;131(16):1917-1925. doi: 10.4103/0366-6999.238151.


Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice.

Manoury B, Nenan S, Guenon I, Boichot E, Planquois JM, Bertrand CP, Lagente V.

J Inflamm (Lond). 2006 Feb 22;3:2.


Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis.

Lan YW, Choo KB, Chen CM, Hung TH, Chen YB, Hsieh CH, Kuo HP, Chong KY.

Stem Cell Res Ther. 2015 May 20;6:97. doi: 10.1186/s13287-015-0081-6.

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