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Items: 1 to 20 of 102

1.

Polycomb repressive 2 complex-Molecular mechanisms of function.

Kouznetsova VL, Tchekanov A, Li X, Yan X, Tsigelny IF.

Protein Sci. 2019 May 16. doi: 10.1002/pro.3647. [Epub ahead of print] Review.

PMID:
31095801
2.

Role of PRC2-associated factors in stem cells and disease.

Vizán P, Beringer M, Ballaré C, Di Croce L.

FEBS J. 2015 May;282(9):1723-35. doi: 10.1111/febs.13083. Epub 2014 Oct 25. Review.

3.

Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.

Chen S, Jiao L, Shubbar M, Yang X, Liu X.

Mol Cell. 2018 Mar 1;69(5):840-852.e5. doi: 10.1016/j.molcel.2018.01.039.

4.

A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.

Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, Deevy O, Glancy E, Fitzpatrick DJ, Mucha M, Watson A, Rice AM, Chammas P, Huang C, Pratt-Kelly I, Koseki Y, Nakayama M, Ishikura T, Streubel G, Wynne K, Hokamp K, McLysaght A, Ciferri C, Di Croce L, Cagney G, Margueron R, Koseki H, Bracken AP.

Mol Cell. 2018 May 3;70(3):408-421.e8. doi: 10.1016/j.molcel.2018.03.005. Epub 2018 Apr 5.

5.

The polycomb repressive complex 2 is a potential target of SUMO modifications.

Riising EM, Boggio R, Chiocca S, Helin K, Pasini D.

PLoS One. 2008 Jul 16;3(7):e2704. doi: 10.1371/journal.pone.0002704.

6.

Nucleosome-binding activities within JARID2 and EZH1 regulate the function of PRC2 on chromatin.

Son J, Shen SS, Margueron R, Reinberg D.

Genes Dev. 2013 Dec 15;27(24):2663-77. doi: 10.1101/gad.225888.113. Erratum in: Genes Dev. 2014 Apr 15;28(8):921.

7.

Structures of human PRC2 with its cofactors AEBP2 and JARID2.

Kasinath V, Faini M, Poepsel S, Reif D, Feng XA, Stjepanovic G, Aebersold R, Nogales E.

Science. 2018 Feb 23;359(6378):940-944. doi: 10.1126/science.aar5700. Epub 2018 Jan 18.

8.

Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.

Liang SC, Hartwig B, Perera P, Mora-García S, de Leau E, Thornton H, de Lima Alves F, Rappsilber J, Yang S, James GV, Schneeberger K, Finnegan EJ, Turck F, Goodrich J.

PLoS Genet. 2015 Dec 7;11(12):e1005660. doi: 10.1371/journal.pgen.1005660. eCollection 2015 Dec. Erratum in: PLoS Genet. 2016 Feb;12(2):e1005812. de Alves, Flavia Lima [corrected to de Lima Alves, Flavia]; Rapsilber, Juri [corrected to Rappsilber, Juri].

9.

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.

Sanulli S, Justin N, Teissandier A, Ancelin K, Portoso M, Caron M, Michaud A, Lombard B, da Rocha ST, Offer J, Loew D, Servant N, Wassef M, Burlina F, Gamblin SJ, Heard E, Margueron R.

Mol Cell. 2015 Mar 5;57(5):769-783. doi: 10.1016/j.molcel.2014.12.020. Epub 2015 Jan 22.

10.

A Noncanonical Function of Polycomb Repressive Complexes Promotes Human Cytomegalovirus Lytic DNA Replication and Serves as a Novel Cellular Target for Antiviral Intervention.

Svrlanska A, Reichel A, Schilling EM, Scherer M, Stamminger T, Reuter N.

J Virol. 2019 Apr 17;93(9). pii: e02143-18. doi: 10.1128/JVI.02143-18. Print 2019 May 1.

PMID:
30814291
11.

Polycomb repressive complex 2 in embryonic stem cells: an overview.

Jones A, Wang H.

Protein Cell. 2010 Dec;1(12):1056-62. doi: 10.1007/s13238-010-0142-7. Epub 2011 Jan 8. Review.

12.

Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits.

Youmans DT, Schmidt JC, Cech TR.

Genes Dev. 2018 Jun 1;32(11-12):794-805. doi: 10.1101/gad.311936.118. Epub 2018 Jun 11.

13.

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

Oliviero G, Brien GL, Waston A, Streubel G, Jerman E, Andrews D, Doyle B, Munawar N, Wynne K, Crean J, Bracken AP, Cagney G.

Mol Cell Proteomics. 2016 Nov;15(11):3450-3460. Epub 2016 Sep 15.

14.

Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2.

Lee CH, Holder M, Grau D, Saldaña-Meyer R, Yu JR, Ganai RA, Zhang J, Wang M, LeRoy G, Dobenecker MW, Reinberg D, Armache KJ.

Mol Cell. 2018 May 3;70(3):435-448.e5. doi: 10.1016/j.molcel.2018.03.019. Epub 2018 Apr 19.

15.

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.

Shi J, Wang E, Zuber J, Rappaport A, Taylor M, Johns C, Lowe SW, Vakoc CR.

Oncogene. 2013 Feb 14;32(7):930-8. doi: 10.1038/onc.2012.110. Epub 2012 Apr 2.

16.

Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells.

Stojic L, Jasencakova Z, Prezioso C, Stützer A, Bodega B, Pasini D, Klingberg R, Mozzetta C, Margueron R, Puri PL, Schwarzer D, Helin K, Fischle W, Orlando V.

Epigenetics Chromatin. 2011 Sep 5;4:16. doi: 10.1186/1756-8935-4-16.

17.

MicroRNA-323-3p regulates the activity of polycomb repressive complex 2 (PRC2) via targeting the mRNA of embryonic ectoderm development (Eed) gene in mouse embryonic stem cells.

Zhang Y, Teng F, Luo GZ, Wang M, Tong M, Zhao X, Wang L, Wang XJ, Zhou Q.

J Biol Chem. 2013 Aug 16;288(33):23659-65. doi: 10.1074/jbc.M113.475608. Epub 2013 Jul 2.

18.

A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.

Bodega B, Marasca F, Ranzani V, Cherubini A, Della Valle F, Neguembor MV, Wassef M, Zippo A, Lanzuolo C, Pagani M, Orlando V.

Nat Struct Mol Biol. 2017 May;24(5):444-452. doi: 10.1038/nsmb.3392. Epub 2017 Mar 27.

PMID:
28346433
19.

Overexpression of polycomb repressive complex 2 key components EZH2/SUZ12/EED as an unfavorable prognostic marker in cholangiocarcinoma.

Wasenang W, Puapairoj A, Settasatian C, Proungvitaya S, Limpaiboon T.

Pathol Res Pract. 2019 May 13:152451. doi: 10.1016/j.prp.2019.152451. [Epub ahead of print]

PMID:
31126817
20.

Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs.

Grijzenhout A, Godwin J, Koseki H, Gdula MR, Szumska D, McGouran JF, Bhattacharya S, Kessler BM, Brockdorff N, Cooper S.

Development. 2016 Aug 1;143(15):2716-23. doi: 10.1242/dev.123935. Epub 2016 Jun 17.

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