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Items: 1 to 20 of 101

1.

New perspective on the metabolism of AD-1 in vivo: Characterization of a series of dammarane-type derivatives with novel metabolic sites and anticancer mechanisms of active oleanane-type metabolites.

Ding M, Wang X, Zhang Y, Yuan W, Zhang H, Xu L, Wang Z, Lu J, Li W, Zhao Y.

Bioorg Chem. 2019 Apr 29;88:102961. doi: 10.1016/j.bioorg.2019.102961. [Epub ahead of print]

PMID:
31075741
2.

Novel dammarane-type sapogenins from Panax ginseng berry and their biological activities.

Zhao JM, Li N, Zhang H, Wu CF, Piao HR, Zhao YQ.

Bioorg Med Chem Lett. 2011 Feb 1;21(3):1027-31. doi: 10.1016/j.bmcl.2010.12.035. Epub 2010 Dec 10.

PMID:
21216145
3.

Two new dammarane-type triterpene sapogenins from Chinese red ginseng.

Zheng Q, Li Z, Liu J, Han L, Zhang N, Zhang H, Chen J, Li P.

Nat Prod Res. 2016;30(1):95-9. doi: 10.1080/14786419.2015.1038538. Epub 2015 Jul 9.

PMID:
26156746
4.

Gender-related differences in pharmacokinetics, tissue distribution, and excretion of 20(R)-25-methoxyl-dammarane-3β,12β,20-triol and its metabolite in rats and anti-ovarian cancer evaluation.

Ding M, Zhang Y, Wang X, Zhao Y.

J Pharm Biomed Anal. 2018 Sep 5;158:327-338. doi: 10.1016/j.jpba.2018.06.010. Epub 2018 Jun 7.

PMID:
29933225
6.
7.

In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng.

Wang W, Zhao Y, Rayburn ER, Hill DL, Wang H, Zhang R.

Cancer Chemother Pharmacol. 2007 Apr;59(5):589-601. Epub 2006 Aug 22.

PMID:
16924497
8.

20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol, a novel natural product for prostate cancer therapy: activity in vitro and in vivo and mechanisms of action.

Wang W, Wang H, Rayburn ER, Zhao Y, Hill DL, Zhang R.

Br J Cancer. 2008 Feb 26;98(4):792-802. doi: 10.1038/sj.bjc.6604227. Epub 2008 Feb 5.

9.

25-methoxyl-dammarane-3β, 12β, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation through downregulation of testes-specific protease 50 (TSP50) expression.

Wang D, Zhao Y, Wang Y, Rong Y, Qin H, Bao Y, Song Z, Yu C, Sun L, Li Y.

Tumour Biol. 2016 Sep;37(9):11805-11813. Epub 2016 Apr 2.

PMID:
27039397
10.

25-Methoxylprotopanaxadiol derivatives and their anti-proliferative activities.

Liu YF, Yuan HN, Bi XL, Piao HR, Cao JQ, Li W, Wang P, Zhao YQ.

Steroids. 2013 Dec 20;78(14):1305-11. doi: 10.1016/j.steroids.2013.09.010. Epub 2013 Oct 8.

PMID:
24120654
11.

Pharmacokinetics of 20(S)-25-methoxyl-dammarane-3beta, 12beta, 20-triol and its active metabolite after oral and intravenous administration in rat.

Zhang X, Xu J, Zhang D, Gu J, Zhao Y.

Xenobiotica. 2009 Jun;39(6):457-64. doi: 10.1080/00498250902810951.

PMID:
19480551
12.

Stereoselective pharmacokinetics of 25-methoxyl-dammarane-3β,12β,20-triol and its active demethyl-metabolite epimers in rats after oral and intravenous administration.

Shao N, Jiang H, Wang X, Yuan B, Jin Y, Song M, Zhao Y, Xu H.

Fitoterapia. 2017 Jan;116:139-145. doi: 10.1016/j.fitote.2016.12.002. Epub 2016 Dec 8.

PMID:
27940119
13.

Structural identification of neopanaxadiol metabolites in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry.

Geng C, Yin J, Yu X, Yang Y, Liu J, Sun D, Chen F, Wei Z, Meng Q, Liu J.

Rapid Commun Mass Spectrom. 2015 Feb 15;29(3):283-94. doi: 10.1002/rcm.7107.

PMID:
26411626
14.

New triterpenoids from the stems and leaves of Panax ginseng.

Li KK, Yang XB, Yang XW, Liu JX, Gong XJ.

Fitoterapia. 2012 Sep;83(6):1030-5. doi: 10.1016/j.fitote.2012.05.013. Epub 2012 May 25.

PMID:
22634016
15.

Three new dammarane-type triterpene saponins from the leaves of Panax ginseng C.A. Meyer.

Liu GY, Li XW, Wang NB, Zhou HY, Wei W, Gui MY, Yang B, Jin YR.

J Asian Nat Prod Res. 2010 Oct;12(10):865-73. doi: 10.1080/10286020.2010.508035.

PMID:
20924900
16.

Microbial transformation of 20(S)-protopanaxatriol-type saponins by Absidia coerulea.

Chen G, Yang M, Lu Z, Zhang J, Huang H, Liang Y, Guan S, Song Y, Wu L, Guo DA.

J Nat Prod. 2007 Jul;70(7):1203-6. Epub 2007 Jul 13.

PMID:
17629326
17.
18.

Chemical Diversity of Panax ginseng, Panax quinquifolium, and Panax notoginseng.

Kim DH.

J Ginseng Res. 2012 Jan;36(1):1-15. doi: 10.5142/jgr.2012.36.1.1.

19.

Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells.

Wang X, Su GY, Zhao C, Qu FZ, Wang P, Zhao YQ.

J Ginseng Res. 2018 Apr;42(2):133-143. doi: 10.1016/j.jgr.2016.12.014. Epub 2016 Dec 31.

20.

Self-microemulsifying drug-delivery system for improved oral bioavailability of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol: preparation and evaluation.

Cai S, Shi CH, Zhang X, Tang X, Suo H, Yang L, Zhao Y.

Int J Nanomedicine. 2014 Feb 12;9:913-20. doi: 10.2147/IJN.S56894. eCollection 2014.

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