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Items: 1 to 20 of 98

1.

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.

Ward-Caviness CK, de Vries PS, Wiggins KL, Huffman JE, Yanek LR, Bielak LF, Giulianini F, Guo X, Kleber ME, Kacprowski T, Groß S, Petersman A, Davey Smith G, Hartwig FP, Bowden J, Hemani G, Müller-Nuraysid M, Strauch K, Koenig W, Waldenberger M, Meitinger T, Pankratz N, Boerwinkle E, Tang W, Fu YP, Johnson AD, Song C, de Maat MPM, Uitterlinden AG, Franco OH, Brody JA, McKnight B, Chen YI, Psaty BM, Mathias RA, Becker DM, Peyser PA, Smith JA, Bielinski SJ, Ridker PM, Taylor KD, Yao J, Tracy R, Delgado G, Trompet S, Sattar N, Jukema JW, Becker LC, Kardia SLR, Rotter JI, März W, Dörr M, Chasman DI, Dehghan A, O'Donnell CJ, Smith NL, Peters A, Morrison AC.

PLoS One. 2019 May 10;14(5):e0216222. doi: 10.1371/journal.pone.0216222. eCollection 2019.

2.

Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'.

Keavney B, Danesh J, Parish S, Palmer A, Clark S, Youngman L, Delépine M, Lathrop M, Peto R, Collins R.

Int J Epidemiol. 2006 Aug;35(4):935-43. Epub 2006 Jul 26.

PMID:
16870675
3.

Does elevated plasma fibrinogen increase the risk of coronary heart disease? Evidence from a meta-analysis of genetic association studies.

Smith GD, Harbord R, Milton J, Ebrahim S, Sterne JA.

Arterioscler Thromb Vasc Biol. 2005 Oct;25(10):2228-33. Epub 2005 Aug 25.

PMID:
16123313
4.

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression.

Bowden J, Davey Smith G, Burgess S.

Int J Epidemiol. 2015 Apr;44(2):512-25. doi: 10.1093/ije/dyv080. Epub 2015 Jun 6.

5.

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.

Hägg S, Fall T, Ploner A, Mägi R, Fischer K, Draisma HH, Kals M, de Vries PS, Dehghan A, Willems SM, Sarin AP, Kristiansson K, Nuotio ML, Havulinna AS, de Bruijn RF, Ikram MA, Kuningas M, Stricker BH, Franco OH, Benyamin B, Gieger C, Hall AS, Huikari V, Jula A, Järvelin MR, Kaakinen M, Kaprio J, Kobl M, Mangino M, Nelson CP, Palotie A, Samani NJ, Spector TD, Strachan DP, Tobin MD, Whitfield JB, Uitterlinden AG, Salomaa V, Syvänen AC, Kuulasmaa K, Magnusson PK, Esko T, Hofman A, de Geus EJ, Lind L, Giedraitis V, Perola M, Evans A, Ferrières J, Virtamo J, Kee F, Tregouet DA, Arveiler D, Amouyel P, Gianfagna F, Brambilla P, Ripatti S, van Duijn CM, Metspalu A, Prokopenko I, McCarthy MI, Pedersen NL, Ingelsson E; European Network for Genetic and Genomic Epidemiology Consortium.

Int J Epidemiol. 2015 Apr;44(2):578-86. doi: 10.1093/ije/dyv094. Epub 2015 May 27.

6.

Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease.

Song C, Burgess S, Eicher JD, O'Donnell CJ, Johnson AD.

J Am Heart Assoc. 2017 May 26;6(6). pii: e004918. doi: 10.1161/JAHA.116.004918. Review.

7.

Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic.

Bowden J, Del Greco M F, Minelli C, Davey Smith G, Sheehan NA, Thompson JR.

Int J Epidemiol. 2016 Dec 1;45(6):1961-1974. doi: 10.1093/ije/dyw220.

8.

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption.

Hartwig FP, Davey Smith G, Bowden J.

Int J Epidemiol. 2017 Dec 1;46(6):1985-1998. doi: 10.1093/ije/dyx102.

9.

Bone mineral density and risk of type 2 diabetes and coronary heart disease: A Mendelian randomization study.

Gan W, Clarke RJ, Mahajan A, Kulohoma B, Kitajima H, Robertson NR, Rayner NW, Walters RG, Holmes MV, Chen Z, McCarthy MI.

Wellcome Open Res. 2017 Aug 22;2:68. doi: 10.12688/wellcomeopenres.12288.1. eCollection 2017.

10.

Mendelian randomization of blood lipids for coronary heart disease.

Holmes MV, Asselbergs FW, Palmer TM, Drenos F, Lanktree MB, Nelson CP, Dale CE, Padmanabhan S, Finan C, Swerdlow DI, Tragante V, van Iperen EP, Sivapalaratnam S, Shah S, Elbers CC, Shah T, Engmann J, Giambartolomei C, White J, Zabaneh D, Sofat R, McLachlan S; UCLEB consortium, Doevendans PA, Balmforth AJ, Hall AS, North KE, Almoguera B, Hoogeveen RC, Cushman M, Fornage M, Patel SR, Redline S, Siscovick DS, Tsai MY, Karczewski KJ, Hofker MH, Verschuren WM, Bots ML, van der Schouw YT, Melander O, Dominiczak AF, Morris R, Ben-Shlomo Y, Price J, Kumari M, Baumert J, Peters A, Thorand B, Koenig W, Gaunt TR, Humphries SE, Clarke R, Watkins H, Farrall M, Wilson JG, Rich SS, de Bakker PI, Lange LA, Davey Smith G, Reiner AP, Talmud PJ, Kivimäki M, Lawlor DA, Dudbridge F, Samani NJ, Keating BJ, Hingorani AD, Casas JP.

Eur Heart J. 2015 Mar 1;36(9):539-50. doi: 10.1093/eurheartj/eht571. Epub 2014 Jan 27.

11.

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.

Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, Trompet S, Chasman DI, Lumley T, Völker U, Buckley BM, Ding J, Jensen MK, Folsom AR, Kritchevsky SB, Girman CJ, Ford I, Dörr M, Salomaa V, Uitterlinden AG, Eiriksdottir G, Vasan RS, Franceschini N, Carty CL, Virtamo J, Demissie S, Amouyel P, Arveiler D, Heckbert SR, Ferrières J, Ducimetière P, Smith NL, Wang YA, Siscovick DS, Rice KM, Wiklund PG, Taylor KD, Evans A, Kee F, Rotter JI, Karvanen J, Kuulasmaa K, Heiss G, Kraft P, Launer LJ, Hofman A, Markus MR, Rose LM, Silander K, Wagner P, Benjamin EJ, Lohman K, Stott DJ, Rivadeneira F, Harris TB, Levy D, Liu Y, Rimm EB, Jukema JW, Völzke H, Ridker PM, Blankenberg S, Franco OH, Gudnason V, Psaty BM, Boerwinkle E, O'Donnell CJ.

PLoS One. 2016 Mar 7;11(3):e0144997. doi: 10.1371/journal.pone.0144997. eCollection 2016.

12.

Exploring the Causal Pathway From Telomere Length to Coronary Heart Disease: A Network Mendelian Randomization Study.

Zhan Y, Karlsson IK, Karlsson R, Tillander A, Reynolds CA, Pedersen NL, Hägg S.

Circ Res. 2017 Jul 21;121(3):214-219. doi: 10.1161/CIRCRESAHA.116.310517. Epub 2017 May 17.

PMID:
28515044
13.

Role of Adiponectin in Coronary Heart Disease Risk: A Mendelian Randomization Study.

Borges MC, Lawlor DA, de Oliveira C, White J, Horta BL, Barros AJ.

Circ Res. 2016 Jul 22;119(3):491-9. doi: 10.1161/CIRCRESAHA.116.308716. Epub 2016 Jun 1.

14.

Relative effects of LDL-C on ischemic stroke and coronary disease: A Mendelian randomization study.

Valdes-Marquez E, Parish S, Clarke R, Stari T, Worrall BB; METASTROKE Consortium of the ISGC,, Hopewell JC.

Neurology. 2019 Mar 12;92(11):e1176-e1187. doi: 10.1212/WNL.0000000000007091. Epub 2019 Feb 20.

15.

Mendelian randomization to assess causal effects of blood lipids on coronary heart disease: lessons from the past and applications to the future.

Burgess S, Harshfield E.

Curr Opin Endocrinol Diabetes Obes. 2016 Apr;23(2):124-30. doi: 10.1097/MED.0000000000000230. Review.

16.

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

Dale CE, Fatemifar G, Palmer TM, White J, Prieto-Merino D, Zabaneh D, Engmann JEL, Shah T, Wong A, Warren HR, McLachlan S, Trompet S, Moldovan M, Morris RW, Sofat R, Kumari M, Hyppönen E, Jefferis BJ, Gaunt TR, Ben-Shlomo Y, Zhou A, Gentry-Maharaj A, Ryan A; UCLEB Consortium; METASTROKE Consortium, Mutsert R, Noordam R, Caulfield MJ, Jukema JW, Worrall BB, Munroe PB, Menon U, Power C, Kuh D, Lawlor DA, Humphries SE, Mook-Kanamori DO, Sattar N, Kivimaki M, Price JF, Davey Smith G, Dudbridge F, Hingorani AD, Holmes MV, Casas JP.

Circulation. 2017 Jun 13;135(24):2373-2388. doi: 10.1161/CIRCULATIONAHA.116.026560. Epub 2017 May 12.

17.

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy.

Rees JMB, Wood AM, Burgess S.

Stat Med. 2017 Dec 20;36(29):4705-4718. doi: 10.1002/sim.7492. Epub 2017 Sep 27.

18.

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.

Budu-Aggrey A, Brumpton B, Tyrrell J, Watkins S, Modalsli EH, Celis-Morales C, Ferguson LD, Vie GÅ, Palmer T, Fritsche LG, Løset M, Nielsen JB, Zhou W, Tsoi LC, Wood AR, Jones SE, Beaumont R, Saunes M, Romundstad PR, Siebert S, McInnes IB, Elder JT, Davey Smith G, Frayling TM, Åsvold BO, Brown SJ, Sattar N, Paternoster L.

PLoS Med. 2019 Jan 31;16(1):e1002739. doi: 10.1371/journal.pmed.1002739. eCollection 2019 Jan.

19.

Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.

Fibrinogen Studies Collaboration, Danesh J, Lewington S, Thompson SG, Lowe GD, Collins R, Kostis JB, Wilson AC, Folsom AR, Wu K, Benderly M, Goldbourt U, Willeit J, Kiechl S, Yarnell JW, Sweetnam PM, Elwood PC, Cushman M, Psaty BM, Tracy RP, Tybjaerg-Hansen A, Haverkate F, de Maat MP, Fowkes FG, Lee AJ, Smith FB, Salomaa V, Harald K, Rasi R, Vahtera E, Jousilahti P, Pekkanen J, D'Agostino R, Kannel WB, Wilson PW, Tofler G, Arocha-Piñango CL, Rodriguez-Larralde A, Nagy E, Mijares M, Espinosa R, Rodriquez-Roa E, Ryder E, Diez-Ewald MP, Campos G, Fernandez V, Torres E, Marchioli R, Valagussa F, Rosengren A, Wilhelmsen L, Lappas G, Eriksson H, Cremer P, Nagel D, Curb JD, Rodriguez B, Yano K, Salonen JT, Nyyssönen K, Tuomainen TP, Hedblad B, Lind P, Loewel H, Koenig W, Meade TW, Cooper JA, De Stavola B, Knottenbelt C, Miller GJ, Cooper JA, Bauer KA, Rosenberg RD, Sato S, Kitamura A, Naito Y, Palosuo T, Ducimetiere P, Amouyel P, Arveiler D, Evans AE, Ferrieres J, Juhan-Vague I, Bingham A, Schulte H, Assmann G, Cantin B, Lamarche B, Després JP, Dagenais GR, Tunstall-Pedoe H, Woodward M, Ben-Shlomo Y, Davey Smith G, Palmieri V, Yeh JL, Rudnicka A, Ridker P, Rodeghiero F, Tosetto A, Shepherd J, Ford I, Robertson M, Brunner E, Shipley M, Feskens EJ, Kromhout D, Dickinson A, Ireland B, Juzwishin K, Kaptoge S, Lewington S, Memon A, Sarwar N, Walker M, Wheeler J, White I, Wood A.

JAMA. 2005 Oct 12;294(14):1799-809. Erratum in: JAMA. 2005 Dec 14;294(22):2848.

20.

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

Prins BP, Abbasi A, Wong A, Vaez A, Nolte I, Franceschini N, Stuart PE, Guterriez Achury J, Mistry V, Bradfield JP, Valdes AM, Bras J, Shatunov A; PAGE Consortium; International Stroke Genetics Consortium; Systemic Sclerosis consortium; Treat OA consortium; DIAGRAM Consortium; CARDIoGRAMplusC4D Consortium; ALS consortium; International Parkinson’s Disease Genomics Consortium; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; CKDGen consortium; GERAD1 Consortium; International Consortium for Blood Pressure; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Inflammation Working Group of the CHARGE Consortium, Lu C, Han B, Raychaudhuri S, Bevan S, Mayes MD, Tsoi LC, Evangelou E, Nair RP, Grant SF, Polychronakos C, Radstake TR, van Heel DA, Dunstan ML, Wood NW, Al-Chalabi A, Dehghan A, Hakonarson H, Markus HS, Elder JT, Knight J, Arking DE, Spector TD, Koeleman BP, van Duijn CM, Martin J, Morris AP, Weersma RK, Wijmenga C, Munroe PB, Perry JR, Pouget JG, Jamshidi Y, Snieder H, Alizadeh BZ.

PLoS Med. 2016 Jun 21;13(6):e1001976. doi: 10.1371/journal.pmed.1001976. eCollection 2016 Jun.

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