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Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet.

Griffin LE, Fausnacht DW, Tuzo JL, Addington AK, Racine KC, Zhang H, Hughes MD, England KM, Bruno RS, O'Keefe SF, Neilson AP, Stewart AC.

Nutr Res. 2019 Jun;66:32-47. doi: 10.1016/j.nutres.2019.03.011. Epub 2019 Mar 21.


Dietary supplementation with Agaricus blazei murill extract prevents diet-induced obesity and insulin resistance in rats.

Vincent M, Philippe E, Everard A, Kassis N, Rouch C, Denom J, Takeda Y, Uchiyama S, Delzenne NM, Cani PD, Migrenne S, Magnan C.

Obesity (Silver Spring). 2013 Mar;21(3):553-61. doi: 10.1002/oby.20276.


Oligomeric cocoa procyanidins possess enhanced bioactivity compared to monomeric and polymeric cocoa procyanidins for preventing the development of obesity, insulin resistance, and impaired glucose tolerance during high-fat feeding.

Dorenkott MR, Griffin LE, Goodrich KM, Thompson-Witrick KA, Fundaro G, Ye L, Stevens JR, Ali M, O'Keefe SF, Hulver MW, Neilson AP.

J Agric Food Chem. 2014 Mar 12;62(10):2216-27. doi: 10.1021/jf500333y. Epub 2014 Mar 3.


Alterations to metabolically active bacteria in the mucosa of the small intestine predict anti-obesity and anti-diabetic activities of grape seed extract in mice.

Griffin LE, Witrick KA, Klotz C, Dorenkott MR, Goodrich KM, Fundaro G, McMillan RP, Hulver MW, Ponder MA, Neilson AP.

Food Funct. 2017 Oct 18;8(10):3510-3522. doi: 10.1039/c7fo01236e.


Dietary supplementation of chinese ginseng prevents obesity and metabolic syndrome in high-fat diet-fed mice.

Li X, Luo J, Anandh Babu PV, Zhang W, Gilbert E, Cline M, McMillan R, Hulver M, Alkhalidy H, Zhen W, Zhang H, Liu D.

J Med Food. 2014 Dec;17(12):1287-97. doi: 10.1089/jmf.2014.0016.


Effect of feeding grape pomace on selected metabolic parameters associated with high fructose feeding in growing Sprague-Dawley rats.

Khanal RC, Howard LR, Rogers TJ, Wilkes SE, Dhakal IB, Prior RL.

J Med Food. 2011 Dec;14(12):1562-9. doi: 10.1089/jmf.2010.0281. Epub 2011 Aug 23.


Dietary cocoa ameliorates obesity-related inflammation in high fat-fed mice.

Gu Y, Yu S, Lambert JD.

Eur J Nutr. 2014 Feb;53(1):149-58. doi: 10.1007/s00394-013-0510-1. Epub 2013 Mar 15.


Leucine supplementation at the onset of high-fat feeding does not prevent weight gain or improve glycemic regulation in male Sprague-Dawley rats.

Baum JI, Washington TA, Shouse SA, Bottje W, Dridi S, Davis G, Smith D.

J Physiol Biochem. 2016 Dec;72(4):781-789. Epub 2016 Aug 20.


Chitooligosaccharide ameliorates diet-induced obesity in mice and affects adipose gene expression involved in adipogenesis and inflammation.

Choi EH, Yang HP, Chun HS.

Nutr Res. 2012 Mar;32(3):218-28. doi: 10.1016/j.nutres.2012.02.004.


Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet.

Terra X, Montagut G, Bustos M, Llopiz N, Ardèvol A, Bladé C, Fernández-Larrea J, Pujadas G, Salvadó J, Arola L, Blay M.

J Nutr Biochem. 2009 Mar;20(3):210-8. doi: 10.1016/j.jnutbio.2008.02.005. Epub 2008 Jul 7.


Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity.

Judge MK, Zhang J, Tümer N, Carter C, Daniels MJ, Scarpace PJ.

Am J Physiol Regul Integr Comp Physiol. 2008 Sep;295(3):R773-80. doi: 10.1152/ajpregu.00727.2007. Epub 2008 Jul 2.


Fish oil prevents changes induced by a high-fat diet on metabolism and adipokine secretion in mice subcutaneous and visceral adipocytes.

de Sá RD, Crisma AR, Cruz MM, Martins AR, Masi LN, do Amaral CL, Curi R, Alonso-Vale MI.

J Physiol. 2016 Nov 1;594(21):6301-6317. doi: 10.1113/JP272541. Epub 2016 Aug 25.


A High-Fat Diet Decreases Bone Mass in Growing Mice with Systemic Chronic Inflammation Induced by Low-Dose, Slow-Release Lipopolysaccharide Pellets.

Cao JJ, Gregoire BR, Shen CL.

J Nutr. 2017 Oct;147(10):1909-1916. doi: 10.3945/jn.117.248302. Epub 2017 Aug 16.


Dietary D-psicose reduced visceral fat mass in high-fat diet-induced obese rats.

Chung YM, Hyun Lee J, Youl Kim D, Hwang SH, Hong YH, Kim SB, Jin Lee S, Hye Park C.

J Food Sci. 2012 Feb;77(2):H53-8. doi: 10.1111/j.1750-3841.2011.02571.x.


Mango Supplementation Modulates Gut Microbial Dysbiosis and Short-Chain Fatty Acid Production Independent of Body Weight Reduction in C57BL/6 Mice Fed a High-Fat Diet.

Ojo B, El-Rassi GD, Payton ME, Perkins-Veazie P, Clarke S, Smith BJ, Lucas EA.

J Nutr. 2016 Aug;146(8):1483-91. doi: 10.3945/jn.115.226688. Epub 2016 Jun 29.


At similar weight loss, dietary composition determines the degree of glycemic improvement in diet-induced obese C57BL/6 mice.

Vangoitsenhoven R, van der Ende M, Corbeels K, Monteiro Carvalho Mori Cunha JP, Lannoo M, Bedossa P, van der Merwe S, Mertens A, Gesquiere I, Meulemans A, Matthys C, Mathieu C, Overbergh L, Van der Schueren B.

PLoS One. 2018 Jul 23;13(7):e0200779. doi: 10.1371/journal.pone.0200779. eCollection 2018.


Grape seed procyanidin supplementation to rats fed a high-fat diet during pregnancy and lactation increases the body fat content and modulates the inflammatory response and the adipose tissue metabolism of the male offspring in youth.

del Bas JM, Crescenti A, Arola-Arnal A, Oms-Oliu G, Arola L, Caimari A.

Int J Obes (Lond). 2015 Jan;39(1):7-15. doi: 10.1038/ijo.2014.159. Epub 2014 Aug 25.


Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity.

van der Heijden RA, Morrison MC, Sheedfar F, Mulder P, Schreurs M, Hommelberg PP, Hofker MH, Schalkwijk C, Kleemann R, Tietge UJ, Koonen DP, Heeringa P.

Mediators Inflamm. 2016;2016:2042107. doi: 10.1155/2016/2042107. Epub 2016 Jun 6.


Suppression of oxidative stress by grape seed supplementation in rats.

Choi SK, Zhang XH, Seo JS.

Nutr Res Pract. 2012 Feb;6(1):3-8. doi: 10.4162/nrp.2012.6.1.3. Epub 2012 Feb 29.


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