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Items: 1 to 20 of 98

1.

Role of mTOR complex in IGF-1 induced neural differentiation of DPSCs.

Huang D, Shen S, Cai M, Jin L, Lu J, Xu K, Zhang J, Feng G, Hu Y, Zheng K, Feng X.

J Mol Histol. 2019 Jun;50(3):273-283. doi: 10.1007/s10735-019-09825-z. Epub 2019 May 2.

PMID:
31049797
2.

Insulin-like growth factor 1 can promote proliferation and osteogenic differentiation of human dental pulp stem cells via mTOR pathway.

Feng X, Huang D, Lu X, Feng G, Xing J, Lu J, Xu K, Xia W, Meng Y, Tao T, Li L, Gu Z.

Dev Growth Differ. 2014 Dec;56(9):615-24. doi: 10.1111/dgd.12179. Epub 2014 Nov 11.

PMID:
25388971
3.

mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR.

Yin Y, Hua H, Li M, Liu S, Kong Q, Shao T, Wang J, Luo Y, Wang Q, Luo T, Jiang Y.

Cell Res. 2016 Jan;26(1):46-65. doi: 10.1038/cr.2015.133. Epub 2015 Nov 20.

4.

Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition.

Damerill I, Biggar KK, Abu Shehab M, Li SS, Jansson T, Gupta MB.

Mol Endocrinol. 2016 Feb;30(2):201-16. doi: 10.1210/me.2015-1194. Epub 2015 Dec 29.

5.

Effects of Nerve Growth Factor and Basic Fibroblast Growth Factor Promote Human Dental Pulp Stem Cells to Neural Differentiation.

Zhang J, Lian M, Cao P, Bao G, Xu G, Sun Y, Wang L, Chen J, Wang Y, Feng G, Cui Z.

Neurochem Res. 2017 Apr;42(4):1015-1025. doi: 10.1007/s11064-016-2134-3. Epub 2016 Dec 22.

PMID:
28005222
6.

Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis.

Kim EK, Yun SJ, Ha JM, Kim YW, Jin IH, Yun J, Shin HK, Song SH, Kim JH, Lee JS, Kim CD, Bae SS.

Oncogene. 2011 Jun 30;30(26):2954-63. doi: 10.1038/onc.2011.22. Epub 2011 Feb 21.

PMID:
21339740
7.

mTORC1 and mTORC2 play different roles in regulating cardiomyocyte differentiation from embryonic stem cells.

Zheng B, Wang J, Tang L, Shi J, Zhu D.

Int J Dev Biol. 2017;61(1-2):65-72. doi: 10.1387/ijdb.160207dz.

8.
9.

mTor plays an important role in odontoblast differentiation.

Kim JK, Baker J, Nor JE, Hill EE.

J Endod. 2011 Aug;37(8):1081-5. doi: 10.1016/j.joen.2011.03.034. Epub 2011 May 28.

PMID:
21763898
10.

Reactive oxygen species and PI3K/Akt signaling in cancer.

Jin SY, Lee HS, Kim EK, Ha JM, Kim YW, Bae S.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S34-5. doi: 10.1016/j.freeradbiomed.2014.10.773. Epub 2014 Dec 10.

PMID:
26461347
11.

Chitosan scaffolds induce human dental pulp stem cells to neural differentiation: potential roles for spinal cord injury therapy.

Zhang J, Lu X, Feng G, Gu Z, Sun Y, Bao G, Xu G, Lu Y, Chen J, Xu L, Feng X, Cui Z.

Cell Tissue Res. 2016 Oct;366(1):129-42. doi: 10.1007/s00441-016-2402-1. Epub 2016 May 5.

PMID:
27147262
12.

Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin.

Han J, Wang B, Xiao Z, Gao Y, Zhao Y, Zhang J, Chen B, Wang X, Dai J.

Mol Cell Neurosci. 2008 Sep;39(1):118-24. doi: 10.1016/j.mcn.2008.06.003. Epub 2008 Jun 17.

PMID:
18620060
13.

Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells.

Zou T, Dissanayaka WL, Jiang S, Wang S, Heng BC, Huang X, Zhang C.

J Endod. 2017 Feb;43(2):297-305. doi: 10.1016/j.joen.2016.10.019. Epub 2016 Dec 24.

PMID:
28027822
14.
15.

Tumor Necrosis Factor Alpha Stimulates Proliferation of Dental Pulp Stem Cells via Akt/Glycogen Synthase Kinase-3β/Cyclin D1 Signaling Pathway.

Qin Z, Li Y, Li Y, Liu G.

J Endod. 2015 Jul;41(7):1066-72. doi: 10.1016/j.joen.2015.02.020. Epub 2015 Apr 3.

PMID:
25843750
16.

Brief report: the differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation.

Martin SK, Fitter S, Dutta AK, Matthews MP, Walkley CR, Hall MN, Ruegg MA, Gronthos S, Zannettino AC.

Stem Cells. 2015 Apr;33(4):1359-65. doi: 10.1002/stem.1931.

17.

Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship.

Jhanwar-Uniyal M, Wainwright JV, Mohan AL, Tobias ME, Murali R, Gandhi CD, Schmidt MH.

Adv Biol Regul. 2019 May;72:51-62. doi: 10.1016/j.jbior.2019.03.003. Epub 2019 Apr 11. Review.

PMID:
31010692
18.

Insulin-like growth factor 1 receptor and p38 mitogen-activated protein kinase signals inversely regulate signal transducer and activator of transcription 3 activity to control human dental pulp stem cell quiescence, propagation, and differentiation.

Vandomme J, Touil Y, Ostyn P, Olejnik C, Flamenco P, El Machhour R, Segard P, Masselot B, Bailliez Y, Formstecher P, Polakowska R.

Stem Cells Dev. 2014 Apr 15;23(8):839-51. doi: 10.1089/scd.2013.0400. Epub 2014 Jan 17.

19.

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.

Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM.

PLoS Biol. 2009 Feb 10;7(2):e38. doi: 10.1371/journal.pbio.1000038.

20.

Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.

Jhanwar-Uniyal M, Gillick JL, Neil J, Tobias M, Thwing ZE, Murali R.

Adv Biol Regul. 2015 Jan;57:64-74. doi: 10.1016/j.jbior.2014.09.004. Epub 2014 Sep 18.

PMID:
25442674

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