Similar articles for PMID: 31043490

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2005	2
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1

Evaluation of Tumor Cell-Tumor Microenvironment Component Interactions as Potential Predictors of Patient Response to Napabucasin.

Chang AY, Hsu E, Patel J, Li Y, Zhang M, Iguchi H, Rogoff HA. Chang AY, et al. Mol Cancer Res. 2019 Jul;17(7):1429-1434. doi: 10.1158/1541-7786.MCR-18-1242. Epub 2019 May 1. Mol Cancer Res. 2019. PMID: 31043490

2

Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell Death.

Froeling FEM, Swamynathan MM, Deschênes A, Chio IIC, Brosnan E, Yao MA, Alagesan P, Lucito M, Li J, Chang AY, Trotman LC, Belleau P, Park Y, Rogoff HA, Watson JD, Tuveson DA. Froeling FEM, et al. Clin Cancer Res. 2019 Dec 1;25(23):7162-7174. doi: 10.1158/1078-0432.CCR-19-0302. Epub 2019 Sep 16. Clin Cancer Res. 2019. PMID: 31527169 Free PMC article.

3

Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial.

Jonker DJ, Nott L, Yoshino T, Gill S, Shapiro J, Ohtsu A, Zalcberg J, Vickers MM, Wei AC, Gao Y, Tebbutt NC, Markman B, Price T, Esaki T, Koski S, Hitron M, Li W, Li Y, Magoski NM, Li CJ, Simes J, Tu D, O'Callaghan CJ. Jonker DJ, et al. Lancet Gastroenterol Hepatol. 2018 Apr;3(4):263-270. doi: 10.1016/S2468-1253(18)30009-8. Epub 2018 Feb 1. Lancet Gastroenterol Hepatol. 2018. PMID: 29397354 Clinical Trial.

4

Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.

Löcken H, Clamor C, Müller K. Löcken H, et al. J Nat Prod. 2018 Jul 27;81(7):1636-1644. doi: 10.1021/acs.jnatprod.8b00247. Epub 2018 Jul 13. J Nat Prod. 2018. PMID: 30003778

5

STAT3 Inhibitor Napabucasin Inhibits Tumor Growth and Cooperates with Proteasome Inhibition in Human Ovarian Cancer Cells.

Liu Y, Peng X, Li H, Jiao W, Peng X, Shao J, Xu Y, Wang R, Wang W, Kong D. Liu Y, et al. Recent Pat Anticancer Drug Discov. 2021;16(3):350-362. doi: 10.2174/1574892816666210224155403. Recent Pat Anticancer Drug Discov. 2021. PMID: 33655847

6

Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo.

Thulin MH, Määttä J, Linder A, Sterbova S, Ohlsson C, Damber JE, Widmark A, Persson E. Thulin MH, et al. Prostate. 2021 Jun;81(8):452-462. doi: 10.1002/pros.24125. Epub 2021 Apr 6. Prostate. 2021. PMID: 33822400

7

Napabucasin, a novel inhibitor of STAT3, inhibits growth and synergises with doxorubicin in diffuse large B-cell lymphoma.

Li X, Wei Y, Wei X. Li X, et al. Cancer Lett. 2020 Oct 28;491:146-161. doi: 10.1016/j.canlet.2020.07.032. Epub 2020 Aug 14. Cancer Lett. 2020. PMID: 32798587 Free article.

8

Discovery of a Napabucasin PROTAC as an Effective Degrader of the E3 Ligase ZFP91.

Hanafi M, Chen X, Neamati N. Hanafi M, et al. J Med Chem. 2021 Feb 11;64(3):1626-1648. doi: 10.1021/acs.jmedchem.0c01897. Epub 2021 Jan 28. J Med Chem. 2021. PMID: 33506674 Free PMC article.

9

Napabucasin, a novel STAT3 inhibitor suppresses proliferation, invasion and stemness of glioblastoma cells.

Han D, Yu T, Dong N, Wang B, Sun F, Jiang D. Han D, et al. J Exp Clin Cancer Res. 2019 Jul 5;38(1):289. doi: 10.1186/s13046-019-1289-6. J Exp Clin Cancer Res. 2019. PMID: 31277685 Free PMC article.

10

A novel series of napabucasin derivatives as orally active inhibitors of signal transducer and activator of transcription 3 (STAT3).

Li C, Chen C, An Q, Yang T, Sang Z, Yang Y, Ju Y, Tong A, Luo Y. Li C, et al. Eur J Med Chem. 2019 Jan 15;162:543-554. doi: 10.1016/j.ejmech.2018.10.067. Epub 2018 Nov 1. Eur J Med Chem. 2019. PMID: 30472602

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