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Comparative validation of an epigenetic mortality risk score with three aging biomarkers for predicting mortality risks among older adult males.

Gao X, Colicino E, Shen J, Just AC, Nwanaji-Enwerem JC, Wang C, Coull B, Lin X, Vokonas P, Zheng Y, Hou L, Schwartz J, Baccarelli AA.

Int J Epidemiol. 2019 Apr 30. pii: dyz082. doi: 10.1093/ije/dyz082. [Epub ahead of print]


Leukocyte telomere length and epigenetic-based mortality risk score: associations with all-cause mortality among older adults.

Gao X, Zhang Y, Mons U, Brenner H.

Epigenetics. 2018;13(8):846-857. doi: 10.1080/15592294.2018.1514853. Epub 2018 Sep 21.


Vitamin D status and epigenetic-based mortality risk score: strong independent and joint prediction of all-cause mortality in a population-based cohort study.

Gao X, Zhang Y, Schöttker B, Brenner H.

Clin Epigenetics. 2018 Jun 20;10:84. doi: 10.1186/s13148-018-0515-y. eCollection 2018.


Smoking-Related DNA Methylation is Associated with DNA Methylation Phenotypic Age Acceleration: The Veterans Affairs Normative Aging Study.

Yang Y, Gao X, Just AC, Colicino E, Wang C, Coull BA, Hou L, Zheng Y, Vokonas P, Schwartz J, Baccarelli AA.

Int J Environ Res Public Health. 2019 Jul 3;16(13). pii: E2356. doi: 10.3390/ijerph16132356.


Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people.

Gao X, Gào X, Zhang Y, Holleczek B, Schöttker B, Brenner H.

Eur J Epidemiol. 2019 May;34(5):451-462. doi: 10.1007/s10654-019-00493-7. Epub 2019 Feb 15.


Accelerated DNA methylation age and the use of antihypertensive medication among older adults.

Gao X, Colicino E, Shen J, Just AC, Nwanaji-Enwerem JC, Wang C, Coull B, Lin X, Vokonas P, Zheng Y, Hou L, Schwartz J, Baccarelli AA.

Aging (Albany NY). 2018 Nov 10;10(11):3210-3228. doi: 10.18632/aging.101626. Erratum in: Aging (Albany NY). 2019 May 15;11(9):2911.


DNA methylation changes in response to active smoking exposure are associated with leukocyte telomere length among older adults.

Gao X, Mons U, Zhang Y, Breitling LP, Brenner H.

Eur J Epidemiol. 2016 Dec;31(12):1231-1241. doi: 10.1007/s10654-016-0210-2. Epub 2016 Nov 10.


Epigenetic drift in the aging genome: a ten-year follow-up in an elderly twin cohort.

Tan Q, Heijmans BT, Hjelmborg JV, Soerensen M, Christensen K, Christiansen L.

Int J Epidemiol. 2016 Aug;45(4):1146-1158. Epub 2016 Aug 6.


Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort.

Perna L, Zhang Y, Mons U, Holleczek B, Saum KU, Brenner H.

Clin Epigenetics. 2016 Jun 3;8:64. doi: 10.1186/s13148-016-0228-z. eCollection 2016.


Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins.

Starnawska A, Tan Q, Lenart A, McGue M, Mors O, Børglum AD, Christensen K, Nyegaard M, Christiansen L.

Neurobiol Aging. 2017 Feb;50:60-63. doi: 10.1016/j.neurobiolaging.2016.10.025. Epub 2016 Nov 4.


DNA methylation-based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies.

Dugué PA, Bassett JK, Joo JE, Jung CH, Ming Wong E, Moreno-Betancur M, Schmidt D, Makalic E, Li S, Severi G, Hodge AM, Buchanan DD, English DR, Hopper JL, Southey MC, Giles GG, Milne RL.

Int J Cancer. 2018 Apr 15;142(8):1611-1619. doi: 10.1002/ijc.31189. Epub 2017 Dec 18.


Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities).

Roetker NS, Pankow JS, Bressler J, Morrison AC, Boerwinkle E.

Circ Genom Precis Med. 2018 Mar;11(3):e001937. doi: 10.1161/CIRCGEN.117.001937.


Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.

Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H.

Hum Mol Genet. 2014 Mar 1;23(5):1186-201. doi: 10.1093/hmg/ddt531. Epub 2013 Oct 26.


Aging, exceptional longevity and comparisons of the Hannum and Horvath epigenetic clocks.

Armstrong NJ, Mather KA, Thalamuthu A, Wright MJ, Trollor JN, Ames D, Brodaty H, Schofield PR, Sachdev PS, Kwok JB.

Epigenomics. 2017 May;9(5):689-700. doi: 10.2217/epi-2016-0179. Epub 2017 May 4.


Tobacco smoking and smoking-related DNA methylation are associated with the development of frailty among older adults.

Gao X, Zhang Y, Saum KU, Schöttker B, Breitling LP, Brenner H.

Epigenetics. 2017 Feb;12(2):149-156. doi: 10.1080/15592294.2016.1271855. Epub 2016 Dec 21.


Frailty is associated with the epigenetic clock but not with telomere length in a German cohort.

Breitling LP, Saum KU, Perna L, Schöttker B, Holleczek B, Brenner H.

Clin Epigenetics. 2016 Feb 26;8:21. doi: 10.1186/s13148-016-0186-5. eCollection 2016.


A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study.

Liu Z, Kuo PL, Horvath S, Crimmins E, Ferrucci L, Levine M.

PLoS Med. 2018 Dec 31;15(12):e1002718. doi: 10.1371/journal.pmed.1002718. eCollection 2018 Dec. Erratum in: PLoS Med. 2019 Feb 25;16(2):e1002760.


Shift work, DNA methylation and epigenetic age.

White AJ, Kresovich JK, Xu Z, Sandler DP, Taylor JA.

Int J Epidemiol. 2019 Mar 15. pii: dyz027. doi: 10.1093/ije/dyz027. [Epub ahead of print]


The impact of methylation quantitative trait loci (mQTLs) on active smoking-related DNA methylation changes.

Gao X, Thomsen H, Zhang Y, Breitling LP, Brenner H.

Clin Epigenetics. 2017 Aug 17;9:87. doi: 10.1186/s13148-017-0387-6. eCollection 2017.


Leukocyte telomere length, T cell composition and DNA methylation age.

Chen BH, Carty CL, Kimura M, Kark JD, Chen W, Li S, Zhang T, Kooperberg C, Levy D, Assimes T, Absher D, Horvath S, Reiner AP, Aviv A.

Aging (Albany NY). 2017 Sep 20;9(9):1983-1995. doi: 10.18632/aging.101293.

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