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Comprehensive kinome NGS targeted expression profiling by KING-REX.

Carapezza G, Cusi C, Rizzo E, Raddrizzani L, Di Bella S, Somaschini A, Leone A, Lupi R, Mutarelli M, Nigro V, di Bernardo D, Magni P, Isacchi A, Bosotti R.

BMC Genomics. 2019 Apr 23;20(1):307. doi: 10.1186/s12864-019-5676-3.


Kinase analysis of penile squamous cell carcinoma on multiple platforms to identify potential therapeutic targets.

Yang ES, Willey CD, Mehta A, Crowley MR, Crossman DK, Chen D, Anderson JC, Naik G, Della Manna DL, Cooper TS, Sonpavde G.

Oncotarget. 2017 Mar 28;8(13):21710-21718. doi: 10.18632/oncotarget.15558.


A targeted quantitative proteomics strategy for global kinome profiling of cancer cells and tissues.

Xiao Y, Guo L, Wang Y.

Mol Cell Proteomics. 2014 Apr;13(4):1065-75. doi: 10.1074/mcp.M113.036905. Epub 2014 Feb 11.


Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.

Bailey FP, Clarke K, Kalirai H, Kenyani J, Shahidipour H, Falciani F, Coulson JM, Sacco JJ, Coupland SE, Eyers PA.

Pigment Cell Melanoma Res. 2018 Mar;31(2):253-266. doi: 10.1111/pcmr.12650. Epub 2017 Oct 15. Review.


The Human Kinome Targeted by FDA Approved Multi-Target Drugs and Combination Products: A Comparative Study from the Drug-Target Interaction Network Perspective.

Li YH, Wang PP, Li XX, Yu CY, Yang H, Zhou J, Xue WW, Tan J, Zhu F.

PLoS One. 2016 Nov 9;11(11):e0165737. doi: 10.1371/journal.pone.0165737. eCollection 2016.


Targeted next-generation-sequencing for reliable detection of targetable rearrangements in lung adenocarcinoma-a single center retrospective study.

Velizheva NP, Rechsteiner MP, Valtcheva N, Freiberger SN, Wong CE, Vrugt B, Zhong Q, Wagner U, Moch H, Hillinger S, Schmitt-Opitz I, Soltermann A, Wild PJ, Tischler V.

Pathol Res Pract. 2018 Apr;214(4):572-578. doi: 10.1016/j.prp.2018.02.001. Epub 2018 Feb 16.


Identification and Validation of Driver Kinases from Next-Generation Sequencing Data.

Leonidou A, Peck B, Natrajan R.

Methods Mol Biol. 2017;1636:179-195. doi: 10.1007/978-1-4939-7154-1_12.


Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines.

Ha KC, Lalonde E, Li L, Cavallone L, Natrajan R, Lambros MB, Mitsopoulos C, Hakas J, Kozarewa I, Fenwick K, Lord CJ, Ashworth A, Vincent-Salomon A, Basik M, Reis-Filho JS, Majewski J, Foulkes WD.

BMC Med Genomics. 2011 Oct 27;4:75. doi: 10.1186/1755-8794-4-75.


KinMap: a web-based tool for interactive navigation through human kinome data.

Eid S, Turk S, Volkamer A, Rippmann F, Fulle S.

BMC Bioinformatics. 2017 Jan 5;18(1):16. doi: 10.1186/s12859-016-1433-7.


System-based drug discovery within the human kinome.

Bamborough P.

Expert Opin Drug Discov. 2012 Nov;7(11):1053-70. doi: 10.1517/17460441.2012.724056. Epub 2012 Sep 13. Review.


Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines.

Gioiosa S, Bolis M, Flati T, Massini A, Garattini E, Chillemi G, Fratelli M, Castrignanò T.

Gigascience. 2018 Oct 1;7(10). doi: 10.1093/gigascience/giy062.


Retinal transcriptome profiling by directional next-generation sequencing using 100 ng of total RNA.

Brooks MJ, Rajasimha HK, Swaroop A.

Methods Mol Biol. 2012;884:319-34. doi: 10.1007/978-1-61779-848-1_23.


Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications.

Hovelson DH, Udager AM, McDaniel AS, Grivas P, Palmbos P, Tamura S, Lazo de la Vega L, Palapattu G, Veeneman B, El-Sawy L, Sadis SE, Morgan TM, Montgomery JS, Weizer AZ, Day KC, Neamati N, Liebert M, Keller ET, Day ML, Mehra R, Tomlins SA.

Eur Urol. 2018 Dec;74(6):741-753. doi: 10.1016/j.eururo.2018.06.047. Epub 2018 Jul 20.


Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals.

Arend KC, Lenarcic EM, Vincent HA, Rashid N, Lazear E, McDonald IM, Gilbert TS, East MP, Herring LE, Johnson GL, Graves LM, Moorman NJ.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S263-S276. doi: 10.1074/mcp.M116.065375. Epub 2017 Feb 25.


Pocketome of human kinases: prioritizing the ATP binding sites of (yet) untapped protein kinases for drug discovery.

Volkamer A, Eid S, Turk S, Jaeger S, Rippmann F, Fulle S.

J Chem Inf Model. 2015 Mar 23;55(3):538-49. doi: 10.1021/ci500624s. Epub 2015 Jan 20.


A kinome wide screen identifies novel kinases involved in regulation of monoamine transporter function.

Vuorenpää A, Ammendrup-Johnsen I, Jørgensen TN, Gether U.

Neurochem Int. 2016 Sep;98:103-14. doi: 10.1016/j.neuint.2016.03.013. Epub 2016 Mar 26.


Identification of novel fusion transcripts in multiple myeloma.

Lin M, Lee PL, Chiu L, Chua C, Ban KHK, Lin AHF, Chan ZL, Chung TH, Yan B, Chng WJ.

J Clin Pathol. 2018 Aug;71(8):708-712. doi: 10.1136/jclinpath-2017-204961. Epub 2018 Feb 16.


Cardiac protein kinases: the cardiomyocyte kinome and differential kinase expression in human failing hearts.

Fuller SJ, Osborne SA, Leonard SJ, Hardyman MA, Vaniotis G, Allen BG, Sugden PH, Clerk A.

Cardiovasc Res. 2015 Oct 1;108(1):87-98. doi: 10.1093/cvr/cvv210. Epub 2015 Aug 10.


Large-scale proteomics analysis of the human kinome.

Oppermann FS, Gnad F, Olsen JV, Hornberger R, Greff Z, Kéri G, Mann M, Daub H.

Mol Cell Proteomics. 2009 Jul;8(7):1751-64. doi: 10.1074/mcp.M800588-MCP200. Epub 2009 Apr 15.


Presence and utility of intrinsically disordered regions in kinases.

Kathiriya JJ, Pathak RR, Clayman E, Xue B, Uversky VN, Davé V.

Mol Biosyst. 2014 Nov;10(11):2876-88. doi: 10.1039/c4mb00224e.


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