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Items: 1 to 20 of 101

1.

The Proton Pump Inhibitor Lansoprazole Has Hepatoprotective Effects in In Vitro and In Vivo Rat Models of Acute Liver Injury.

Nakatake R, Hishikawa H, Kotsuka M, Ishizaki M, Matsui K, Nishizawa M, Yoshizawa K, Kaibori M, Okumura T.

Dig Dis Sci. 2019 Oct;64(10):2854-2866. doi: 10.1007/s10620-019-05622-6. Epub 2019 Apr 15.

PMID:
30989463
2.

Elental® amino acid component has protective effects on primary cultured hepatocytes and a rat model of acute liver injury.

Miki H, Tokuhara K, Oishi M, Tanaka Y, Nakatake R, Ueyama Y, Kaibori M, Nishizawa M, Okumura T, Kon M.

Nutr Res. 2017 Jun;42:71-84. doi: 10.1016/j.nutres.2017.04.010. Epub 2017 May 5.

PMID:
28633873
3.

Protective effect of neutrophil elastase inhibitor (FR136706) in lethal acute liver failure induced by D-galactosamine and lipopolysaccharide in rats.

Uchida Y, Kaibori M, Hijikawa T, Ishizaki M, Ozaki T, Tanaka H, Matsui K, Tokuhara K, Kwon AH, Kamiyama Y, Okumura T.

J Surg Res. 2008 Mar;145(1):57-65. Epub 2007 Oct 22.

PMID:
17936791
4.

Genipin Inhibits the Induction of Inducible Nitric Oxide Synthase Through the Inhibition of NF-κB Activation in Rat Hepatocytes.

Nakatake R, Tsuda T, Matsuura T, Miki H, Hishikawa H, Matsushima H, Ishizaki M, Matsui K, Kaibori M, Nishizawa M, Okumura T, Kon M.

Drug Metab Lett. 2017;10(4):254-263. doi: 10.2174/1872312810666161020164658.

PMID:
27774888
5.

Alpha-lipoic acid exerts a liver-protective effect in acute liver injury rats.

Tanaka Y, Kaibori M, Miki H, Nakatake R, Tokuhara K, Nishizawa M, Okumura T, Kwon AH.

J Surg Res. 2015 Feb;193(2):675-83. doi: 10.1016/j.jss.2014.08.057. Epub 2014 Sep 4.

PMID:
25266599
6.

pyroGlu-Leu inhibits the induction of inducible nitric oxide synthase in interleukin-1β-stimulated primary cultured rat hepatocytes.

Oishi M, Kiyono T, Sato K, Tokuhara K, Tanaka Y, Miki H, Nakatake R, Kaibori M, Nishizawa M, Okumura T, Kon M.

Nitric Oxide. 2015 Jan 30;44:81-7. doi: 10.1016/j.niox.2014.12.005. Epub 2014 Dec 12.

PMID:
25512333
7.

Na+/H+ exchanger inhibitor, FR183998, has protective effect in lethal acute liver failure and prevents iNOS induction in rats.

Tanaka H, Uchida Y, Kaibori M, Hijikawa T, Ishizaki M, Yamada M, Matsui K, Ozaki T, Tokuhara K, Kamiyama Y, Nishizawa M, Ito S, Okumura T.

J Hepatol. 2008 Feb;48(2):289-99. Epub 2007 Dec 10.

PMID:
18096265
8.

Insulin-like growth factor 1 prevents liver injury through the inhibition of TNF-alpha and iNOS induction in D-galactosamine and LPS-treated rats.

Hijikawa T, Kaibori M, Uchida Y, Yamada M, Matsui K, Ozaki T, Kamiyama Y, Nishizawa M, Okumura T.

Shock. 2008 Jun;29(6):740-7.

PMID:
18004231
9.

Japanese Kampo Saireito Has a Liver-Protective Effect Through the Inhibition of Inducible Nitric Oxide Synthase Induction in Primary Cultured Rat Hepatocytes.

Miki H, Tokuhara K, Oishi M, Nakatake R, Tanaka Y, Kaibori M, Nishizawa M, Okumura T, Kon M.

JPEN J Parenter Enteral Nutr. 2016 Sep;40(7):1033-41. doi: 10.1177/0148607115575035. Epub 2015 Mar 9.

PMID:
25754438
10.

The role of STAT1/IRF-1 on synergistic ROS production and loss of mitochondrial transmembrane potential during hepatic cell death induced by LPS/d-GalN.

Lee HJ, Oh YK, Rhee M, Lim JY, Hwang JY, Park YS, Kwon Y, Choi KH, Jo I, Park SI, Gao B, Kim WH.

J Mol Biol. 2007 Jun 15;369(4):967-84. Epub 2007 Apr 1.

PMID:
17475277
11.

Effects of globin digest and its active ingredient Trp-Thr-Gln-Arg on galactosamine/lipopolysaccharide-induced liver injury in ICR mice.

Sasakawa Y, Kominami A, Yamamoto K, Nakaoka F, Nakamura M, Nakao M, Abe M, Fukuhama C, Kagawa K.

Life Sci. 2012 Jan 30;90(5-6):190-9. doi: 10.1016/j.lfs.2011.11.013. Epub 2011 Dec 1.

PMID:
22154906
12.

CQMUH-011, a novel adamantane sulfonamide compound, inhibits lipopolysaccharide- and D-galactosamine-induced fulminant hepatic failure in mice.

Yan L, Hu X, Wu Q, Jiang R, Zhang S, Ling Q, Liu H, Jiang X, Wan J, Liu Y.

Int Immunopharmacol. 2017 Jun;47:231-243. doi: 10.1016/j.intimp.2017.04.015. Epub 2017 Apr 25.

PMID:
28433945
13.
14.

BML-111 Protected LPS/D-GalN-Induced Acute Liver Injury in Rats.

Yan D, Liu HL, Yu ZJ, Huang YH, Gao D, Hao H, Liao SS, Xu FY, Zhou XY.

Int J Mol Sci. 2016 Jul 13;17(7). pii: E1114. doi: 10.3390/ijms17071114.

15.

Protective Effects of Sesquiterpenoids from the Root of Panax ginseng on Fulminant Liver Injury Induced by Lipopolysaccharide/d-Galactosamine.

Wang W, Zhang Y, Li H, Zhao Y, Cai E, Zhu H, Li P, Liu J.

J Agric Food Chem. 2018 Jul 25;66(29):7758-7763. doi: 10.1021/acs.jafc.8b02627. Epub 2018 Jul 16.

PMID:
29974747
16.

Madecassoside prevents acute liver failure in LPS/D-GalN-induced mice by inhibiting p38/NF-κB and activating Nrf2/HO-1 signaling.

Wang W, Wu L, Li Q, Zhang Z, Xu L, Lin C, Gao L, Zhao K, Liang F, Zhang Q, Zhou M, Jiang W.

Biomed Pharmacother. 2018 Jul;103:1137-1145. doi: 10.1016/j.biopha.2018.04.162. Epub 2018 Apr 27.

PMID:
29715757
17.

Genistein modulates the expression of NF-κB and MAPK (p-38 and ERK1/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats.

Ganai AA, Khan AA, Malik ZA, Farooqi H.

Toxicol Appl Pharmacol. 2015 Mar 1;283(2):139-46. doi: 10.1016/j.taap.2015.01.012. Epub 2015 Jan 22.

PMID:
25620059
18.

Baicalein inhibits nuclear factor-κB and apoptosis via c-FLIP and MAPK in D-GalN/LPS induced acute liver failure in murine models.

Wu YL, Lian LH, Wan Y, Nan JX.

Chem Biol Interact. 2010 Dec 5;188(3):526-34. doi: 10.1016/j.cbi.2010.09.008. Epub 2010 Sep 17.

PMID:
20850421
19.

Effect of thiol-containing molecule cysteamine on the induction of inducible nitric oxide synthase in hepatocytes.

Ozaki T, Kaibori M, Matsui K, Tokuhara K, Tanaka H, Kamiyama Y, Nishizawa M, Ito S, Okumura T.

JPEN J Parenter Enteral Nutr. 2007 Sep-Oct;31(5):366-71; discussion 371-2.

PMID:
17712144
20.

alpha-lipoic acid prevents the induction of iNOS gene expression through destabilization of its mRNA in proinflammatory cytokine-stimulated hepatocytes.

Yamada M, Kaibori M, Tanaka H, Habara K, Hijikawa T, Tanaka Y, Oishi M, Okumura T, Nishizawa M, Kwon AH.

Dig Dis Sci. 2012 Apr;57(4):943-51. doi: 10.1007/s10620-011-2012-4. Epub 2012 Jan 3.

PMID:
22212728

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