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Items: 1 to 20 of 98

1.

Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.

Ronsisvalle S, Spadaro A, Tomasello B, Basile L, Panarello F, Franchini S, Renis M, Guccione S, Crascì L, Panico AM.

Future Med Chem. 2019 Jun;11(11):1245-1258. doi: 10.4155/fmc-2018-0535. Epub 2019 Apr 12.

PMID:
30974972
2.

Antinociceptive profile of LP1, a non-peptide multitarget opioid ligand.

Parenti C, Turnaturi R, Aricò G, Marrazzo A, Prezzavento O, Ronsisvalle S, Scoto GM, Ronsisvalle G, Pasquinucci L.

Life Sci. 2012 Jun 27;90(25-26):957-61. doi: 10.1016/j.lfs.2012.04.041. Epub 2012 May 11.

PMID:
22580287
3.

Opioids in chronic pain.

Przewłocki R, Przewłocka B.

Eur J Pharmacol. 2001 Oct 19;429(1-3):79-91. Review.

PMID:
11698029
4.

Peripheral μ-opioid receptor mediated inhibition of calcium signaling and action potential-evoked calcium fluorescent transients in primary afferent CGRP nociceptive terminals.

Baillie LD, Schmidhammer H, Mulligan SJ.

Neuropharmacology. 2015 Jun;93:267-73. doi: 10.1016/j.neuropharm.2015.02.011. Epub 2015 Feb 24.

PMID:
25721395
5.

Clinically employed opioid analgesics produce antinociception via μ-δ opioid receptor heteromers in Rhesus monkeys.

Yekkirala AS, Banks ML, Lunzer MM, Negus SS, Rice KC, Portoghese PS.

ACS Chem Neurosci. 2012 Sep 19;3(9):720-7. Epub 2012 Jul 5.

6.

Acute morphine induces matrix metalloproteinase-9 up-regulation in primary sensory neurons to mask opioid-induced analgesia in mice.

Liu YC, Berta T, Liu T, Tan PH, Ji RR.

Mol Pain. 2012 Mar 25;8:19. doi: 10.1186/1744-8069-8-19.

7.

Hydrogen sulphide induces micro opioid receptor-dependent analgesia in a rodent model of visceral pain.

Distrutti E, Cipriani S, Renga B, Mencarelli A, Migliorati M, Cianetti S, Fiorucci S.

Mol Pain. 2010 Jun 11;6:36. doi: 10.1186/1744-8069-6-36.

9.

The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception.

Sarton E, Teppema LJ, Olievier C, Nieuwenhuijs D, Matthes HW, Kieffer BL, Dahan A.

Anesth Analg. 2001 Dec;93(6):1495-500, table of contents.

PMID:
11726430
10.
11.

μ Opioid receptor: novel antagonists and structural modeling.

Kaserer T, Lantero A, Schmidhammer H, Spetea M, Schuster D.

Sci Rep. 2016 Feb 18;6:21548. doi: 10.1038/srep21548.

12.

Bioactivity of new mu and delta opioid peptides.

Capasso A.

Med Chem. 2007 Sep;3(5):480-7.

PMID:
17897075
14.

Mu-opioid Receptor (MOR) Biased Agonists Induce Biphasic Dose-dependent Hyperalgesia and Analgesia, and Hyperalgesic Priming in the Rat.

Araldi D, Ferrari LF, Levine JD.

Neuroscience. 2018 Dec 1;394:60-71. doi: 10.1016/j.neuroscience.2018.10.015. Epub 2018 Oct 17.

PMID:
30342200
15.

Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice.

Weibel R, Reiss D, Karchewski L, Gardon O, Matifas A, Filliol D, Becker JA, Wood JN, Kieffer BL, Gaveriaux-Ruff C.

PLoS One. 2013 Sep 12;8(9):e74706. doi: 10.1371/journal.pone.0074706. eCollection 2013.

16.

Role of mu-opioid agonist efficacy on antinociceptive interactions between mu agonists and the nociceptin opioid peptide agonist Ro 64-6198 in rhesus monkeys.

Cornelissen JC, Steele FF, Tenney RD, Obeng S, Rice KC, Zhang Y, Banks ML.

Eur J Pharmacol. 2019 Feb 5;844:175-182. doi: 10.1016/j.ejphar.2018.12.021. Epub 2018 Dec 12.

PMID:
30552903
17.

Co-administration of δ- and μ-opioid receptor agonists promotes peripheral opioid receptor function.

Schramm CL, Honda CN.

Pain. 2010 Dec;151(3):763-70. doi: 10.1016/j.pain.2010.09.009.

18.

In vitro and in vivo activity of cyclopeptide Dmt-c[d-Lys-Phe-Asp]NH2, a mu opioid receptor agonist biased toward β-arrestin.

Gach-Janczak K, Piekielna-Ciesielska J, Adamska-Bartłomiejczyk A, Wtorek K, Ferrari F, Calo' G, Szymaszkiewicz A, Piasecka-Zelga J, Janecka A.

Peptides. 2018 Jul;105:51-57. doi: 10.1016/j.peptides.2018.04.014. Epub 2018 Apr 22.

PMID:
29684591
19.

Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR Affinities.

Harland AA, Yeomans L, Griggs NW, Anand JP, Pogozheva ID, Jutkiewicz EM, Traynor JR, Mosberg HI.

J Med Chem. 2015 Nov 25;58(22):8952-69. doi: 10.1021/acs.jmedchem.5b01270. Epub 2015 Nov 13.

20.

Interactions between μ-opioid receptor agonists and cannabinoid receptor agonists in rhesus monkeys: antinociception, drug discrimination, and drug self-administration.

Maguire DR, Yang W, France CP.

J Pharmacol Exp Ther. 2013 Jun;345(3):354-62. doi: 10.1124/jpet.113.204099. Epub 2013 Mar 27. Erratum in: J Pharmacol Exp Ther. 2014 Mar;348(3):490-1. Dosage error in article text.

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