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Items: 1 to 20 of 99


A tunable assay for modulators of genome-destabilizing DNA structures.

Del Mundo IMA, Cho EJ, Dalby KN, Vasquez KM.

Nucleic Acids Res. 2019 Jul 26;47(13):e73. doi: 10.1093/nar/gkz237.


Modulation of DNA structure formation using small molecules.

Del Mundo IMA, Vasquez KM, Wang G.

Biochim Biophys Acta Mol Cell Res. 2019 Sep 3:118539. doi: 10.1016/j.bbamcr.2019.118539. [Epub ahead of print] Review.


Alternative DNA structure formation in the mutagenic human c-MYC promoter.

Del Mundo IMA, Zewail-Foote M, Kerwin SM, Vasquez KM.

Nucleic Acids Res. 2017 May 5;45(8):4929-4943. doi: 10.1093/nar/gkx100.


DNA structural basis for fragility at peak III of BCL2 major breakpoint region associated with t(14;18) translocation.

Javadekar SM, Yadav R, Raghavan SC.

Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):649-659. doi: 10.1016/j.bbagen.2017.12.003. Epub 2017 Dec 12.


Detection of cis- and trans-acting Factors in DNA Structure-Induced Genetic Instability Using In silico and Cellular Approaches.

Wang G, Zhao J, Vasquez KM.

Front Genet. 2016 Aug 2;7:135. doi: 10.3389/fgene.2016.00135. eCollection 2016.


Non-B DNA structure-induced genetic instability and evolution.

Zhao J, Bacolla A, Wang G, Vasquez KM.

Cell Mol Life Sci. 2010 Jan;67(1):43-62. doi: 10.1007/s00018-009-0131-2. Epub 2009 Sep 1. Review.


Oligonucleotide Binding to Non-B-DNA in MYC.

Umek T, Sollander K, Bergquist H, Wengel J, Lundin KE, Smith CIE, Zain R.

Molecules. 2019 Mar 12;24(5). pii: E1000. doi: 10.3390/molecules24051000.


Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes.

Lu S, Wang G, Bacolla A, Zhao J, Spitser S, Vasquez KM.

Cell Rep. 2015 Mar 17;10(10):1674-1680. doi: 10.1016/j.celrep.2015.02.039. Epub 2015 Mar 12.


Methods to detect replication-dependent and replication-independent DNA structure-induced genetic instability.

Wang G, Gaddis S, Vasquez KM.

Methods. 2013 Nov;64(1):67-72. doi: 10.1016/j.ymeth.2013.08.004. Epub 2013 Aug 15. Review.


Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes.

Zhao J, Wang G, Del Mundo IM, McKinney JA, Lu X, Bacolla A, Boulware SB, Zhang C, Zhang H, Ren P, Freudenreich CH, Vasquez KM.

Cell Rep. 2018 Jan 30;22(5):1200-1210. doi: 10.1016/j.celrep.2018.01.014.


Triplex-forming MicroRNAs form stable complexes with HIV-1 provirus and inhibit its replication.

Kanak M, Alseiari M, Balasubramanian P, Addanki K, Aggarwal M, Noorali S, Kalsum A, Mahalingam K, Pace G, Panasik N, Bagasra O.

Appl Immunohistochem Mol Morphol. 2010 Dec;18(6):532-45. doi: 10.1097/PAI.0b013e3181e1ef6a.


Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences.

Bacolla A, Tainer JA, Vasquez KM, Cooper DN.

Nucleic Acids Res. 2016 Jul 8;44(12):5673-88. doi: 10.1093/nar/gkw261. Epub 2016 Apr 15.


Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.

Wang G, Vasquez KM.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13448-53. Epub 2004 Sep 1.


Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?

Amato J, Pagano A, Cosconati S, Amendola G, Fotticchia I, Iaccarino N, Marinello J, De Magis A, Capranico G, Novellino E, Pagano B, Randazzo A.

Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1271-1280. doi: 10.1016/j.bbagen.2016.11.008. Epub 2016 Nov 9.


DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells.

Jain A, Bacolla A, Del Mundo IM, Zhao J, Wang G, Vasquez KM.

Nucleic Acids Res. 2013 Dec;41(22):10345-57. doi: 10.1093/nar/gkt804. Epub 2013 Sep 17.


DNA structure-induced genomic instability in vivo.

Wang G, Carbajal S, Vijg J, DiGiovanni J, Vasquez KM.

J Natl Cancer Inst. 2008 Dec 17;100(24):1815-7. doi: 10.1093/jnci/djn385. Epub 2008 Dec 9.


Triplex structures induce DNA double strand breaks via replication fork collapse in NER deficient cells.

Kaushik Tiwari M, Adaku N, Peart N, Rogers FA.

Nucleic Acids Res. 2016 Sep 19;44(16):7742-54. doi: 10.1093/nar/gkw515. Epub 2016 Jun 13.


Non-B DNA structure-induced genetic instability.

Wang G, Vasquez KM.

Mutat Res. 2006 Jun 25;598(1-2):103-19. Epub 2006 Mar 3.


The Lack of Mutagenic Potential of a Guanine-Rich Triplex Forming Oligonucleotide in Physiological Conditions.

Saleh AF, Fellows MD, Ying L, Gooderham NJ, Priestley CC.

Toxicol Sci. 2017 Jan;155(1):101-111. doi: 10.1093/toxsci/kfw179. Epub 2016 Sep 21.

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