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Items: 1 to 20 of 111

1.

Targeting SOCS Proteins to Control JAK-STAT Signalling in Disease.

Durham GA, Williams JJL, Nasim MT, Palmer TM.

Trends Pharmacol Sci. 2019 May;40(5):298-308. doi: 10.1016/j.tips.2019.03.001. Epub 2019 Apr 2. Review.

PMID:
30948191
2.

SOCS regulation of the JAK/STAT signalling pathway.

Croker BA, Kiu H, Nicholson SE.

Semin Cell Dev Biol. 2008 Aug;19(4):414-22. doi: 10.1016/j.semcdb.2008.07.010. Epub 2008 Jul 30. Review.

3.

miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling.

Collins AS, McCoy CE, Lloyd AT, O'Farrelly C, Stevenson NJ.

PLoS One. 2013 Jul 22;8(7):e69090. doi: 10.1371/journal.pone.0069090. Print 2013.

4.
5.

Suppressors of cytokine signaling (SOCS) proteins and JAK/STAT pathways: regulation of T-cell inflammation by SOCS1 and SOCS3.

Tamiya T, Kashiwagi I, Takahashi R, Yasukawa H, Yoshimura A.

Arterioscler Thromb Vasc Biol. 2011 May;31(5):980-5. doi: 10.1161/ATVBAHA.110.207464. Review.

PMID:
21508344
6.

Socs36E limits STAT signaling via Cullin2 and a SOCS-box independent mechanism in the Drosophila egg chamber.

Monahan AJ, Starz-Gaiano M.

Mech Dev. 2015 Nov;138 Pt 3:313-27. doi: 10.1016/j.mod.2015.08.003. Epub 2015 Aug 13.

7.

Inhibition of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling pathway in rheumatoid synovial fibroblasts using small molecule compounds.

Migita K, Izumi Y, Torigoshi T, Satomura K, Izumi M, Nishino Y, Jiuchi Y, Nakamura M, Kozuru H, Nonaka F, Eguchi K, Kawakami A, Motokawa S.

Clin Exp Immunol. 2013 Dec;174(3):356-63. doi: 10.1111/cei.12190.

8.

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.

Slattery ML, Lundgreen A, Kadlubar SA, Bondurant KL, Wolff RK.

Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841. Epub 2011 Nov 28.

9.

Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease.

O'Sullivan LA, Liongue C, Lewis RS, Stephenson SE, Ward AC.

Mol Immunol. 2007 Apr;44(10):2497-506. Epub 2007 Jan 17. Review.

PMID:
17208301
10.

Targeting JAK/STAT signalling in inflammatory skin diseases with small molecule inhibitors.

Welsch K, Holstein J, Laurence A, Ghoreschi K.

Eur J Immunol. 2017 Jul;47(7):1096-1107. doi: 10.1002/eji.201646680. Epub 2017 Jun 21. Review.

11.

[Research Advances of JAK/STAT Signaling Pathway in Lung Cancer].

Yang X, Tang Z, Zhang P, Zhang L.

Zhongguo Fei Ai Za Zhi. 2019 Jan 20;22(1):45-51. doi: 10.3779/j.issn.1009-3419.2019.01.09. Review. Chinese.

12.

Suppressors of cytokine signaling abrogate diabetic nephropathy.

Ortiz-Muñoz G, Lopez-Parra V, Lopez-Franco O, Fernandez-Vizarra P, Mallavia B, Flores C, Sanz A, Blanco J, Mezzano S, Ortiz A, Egido J, Gomez-Guerrero C.

J Am Soc Nephrol. 2010 May;21(5):763-72. doi: 10.1681/ASN.2009060625. Epub 2010 Feb 25.

13.

Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis.

Ortiz-Muñoz G, Martin-Ventura JL, Hernandez-Vargas P, Mallavia B, Lopez-Parra V, Lopez-Franco O, Muñoz-Garcia B, Fernandez-Vizarra P, Ortega L, Egido J, Gomez-Guerrero C.

Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):525-31. doi: 10.1161/ATVBAHA.108.173781. Epub 2009 Jan 22.

PMID:
19164812
14.

Therapeutic targeting of the Jak/STAT pathway.

Aittomäki S, Pesu M.

Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):18-23. doi: 10.1111/bcpt.12164. Epub 2013 Nov 15. Review.

15.

Formal modelling of toll like receptor 4 and JAK/STAT signalling pathways: insight into the roles of SOCS-1, interferon-β and proinflammatory cytokines in sepsis.

Paracha RZ, Ahmad J, Ali A, Hussain R, Niazi U, Tareen SH, Aslam B.

PLoS One. 2014 Sep 25;9(9):e108466. doi: 10.1371/journal.pone.0108466. eCollection 2014.

16.

Targeting the interleukin-6/Jak/stat pathway in human malignancies.

Sansone P, Bromberg J.

J Clin Oncol. 2012 Mar 20;30(9):1005-14. doi: 10.1200/JCO.2010.31.8907. Epub 2012 Feb 21. Review.

17.

MsSOCS expression indicates a potential role for JAK/STAT signalling in the early stages of Manduca sexta spermatogenesis.

Elliott GC, Zeidler MP.

Insect Mol Biol. 2008 Sep;17(5):475-83. doi: 10.1111/j.1365-2583.2008.00804.x.

PMID:
18715265
18.

Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.

Liongue C, O'Sullivan LA, Trengove MC, Ward AC.

PLoS One. 2012;7(3):e32777. doi: 10.1371/journal.pone.0032777. Epub 2012 Mar 7.

19.

Drosophila SOCS36E negatively regulates JAK/STAT pathway signaling via two separable mechanisms.

Stec W, Vidal O, Zeidler MP.

Mol Biol Cell. 2013 Sep;24(18):3000-9. doi: 10.1091/mbc.E13-05-0275. Epub 2013 Jul 24.

20.

SOCS3 revisited: a broad regulator of disease, now ready for therapeutic use?

Mahony R, Ahmed S, Diskin C, Stevenson NJ.

Cell Mol Life Sci. 2016 Sep;73(17):3323-36. doi: 10.1007/s00018-016-2234-x. Epub 2016 May 2. Review.

PMID:
27137184

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