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Items: 1 to 20 of 105

1.

The landscape of the mesenchymal signature in brain tumours.

Behnan J, Finocchiaro G, Hanna G.

Brain. 2019 Apr 1;142(4):847-866. doi: 10.1093/brain/awz044.

2.

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Sauvé CG, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW.

Cancer Cell. 2017 Jul 10;32(1):42-56.e6. doi: 10.1016/j.ccell.2017.06.003. Erratum in: Cancer Cell. 2018 Jan 8;33(1):152.

3.

Angiogenic Gene Signature Derived from Subtype Specific Cell Models Segregate Proneural and Mesenchymal Glioblastoma.

Sharma A, Bendre A, Mondal A, Muzumdar D, Goel N, Shiras A.

Front Oncol. 2017 Jul 11;7:146. doi: 10.3389/fonc.2017.00146. eCollection 2017.

4.

PATZ1 is a new prognostic marker of glioblastoma associated with the stem-like phenotype and enriched in the proneural subtype.

Guadagno E, Vitiello M, Francesca P, Calì G, Caponnetto F, Cesselli D, Camorani S, Borrelli G, Califano M, Cappabianca P, Arra C, Crescenzi E, Cerchia L, De Caro MLDB, Fedele M.

Oncotarget. 2017 Jul 25;8(35):59282-59300. doi: 10.18632/oncotarget.19546. eCollection 2017 Aug 29.

5.

A novel drug conjugate, NEO212, targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells.

Jhaveri N, Agasse F, Armstrong D, Peng L, Commins D, Wang W, Rosenstein-Sisson R, Vaikari VP, Santiago SV, Santos T, Chen L, Schönthal AH, Chen TC, Hofman FM.

Cancer Lett. 2016 Feb 28;371(2):240-50. doi: 10.1016/j.canlet.2015.11.040. Epub 2015 Dec 9.

PMID:
26683773
6.

Oncostatin-M differentially regulates mesenchymal and proneural signature genes in gliomas via STAT3 signaling.

Natesh K, Bhosale D, Desai A, Chandrika G, Pujari R, Jagtap J, Chugh A, Ranade D, Shastry P.

Neoplasia. 2015 Feb;17(2):225-37. doi: 10.1016/j.neo.2015.01.001.

7.

Stem cell signature in glioblastoma: therapeutic development for a moving target.

Nakano I.

J Neurosurg. 2015 Feb;122(2):324-30. doi: 10.3171/2014.9.JNS132253. Epub 2014 Nov 14. Review.

PMID:
25397368
8.

Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas.

Zhang Q, Xiang W, Yi DY, Xue BZ, Wen WW, Abdelmaksoud A, Xiong NX, Jiang XB, Zhao HY, Fu P.

Stem Cell Res Ther. 2018 Aug 24;9(1):228. doi: 10.1186/s13287-018-0977-z. Review.

9.

Prevalence and clinicopathologic characteristics of the molecular subtypes in malignant glioma: a multi-institutional analysis of 941 cases.

Lin N, Yan W, Gao K, Wang Y, Zhang J, You Y.

PLoS One. 2014 Apr 22;9(4):e94871. doi: 10.1371/journal.pone.0094871. eCollection 2014.

10.

Molecular subtypes, stem cells and heterogeneity: Implications for personalised therapy in glioma.

Morokoff A, Ng W, Gogos A, Kaye AH.

J Clin Neurosci. 2015 Aug;22(8):1219-26. doi: 10.1016/j.jocn.2015.02.008. Epub 2015 May 6. Review.

PMID:
25957782
11.

Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.

Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8644-9. doi: 10.1073/pnas.1221478110. Epub 2013 May 6.

12.

Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells.

Chandran UR, Luthra S, Santana-Santos L, Mao P, Kim SH, Minata M, Li J, Benos PV, DeWang M, Hu B, Cheng SY, Nakano I, Sobol RW.

Genom Data. 2015 Sep 1;5:333-336.

13.

Coexpression analysis of CD133 and CD44 identifies proneural and mesenchymal subtypes of glioblastoma multiforme.

Brown DV, Daniel PM, D'Abaco GM, Gogos A, Ng W, Morokoff AP, Mantamadiotis T.

Oncotarget. 2015 Mar 20;6(8):6267-80.

14.

Phospholipase C Beta 1: a Candidate Signature Gene for Proneural Subtype High-Grade Glioma.

Lu G, Chang JT, Liu Z, Chen Y, Li M, Zhu JJ.

Mol Neurobiol. 2016 Nov;53(9):6511-6525. doi: 10.1007/s12035-015-9518-2. Epub 2015 Nov 28.

15.

Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in Glioblastoma.

Fedele M, Cerchia L, Pegoraro S, Sgarra R, Manfioletti G.

Int J Mol Sci. 2019 Jun 4;20(11). pii: E2746. doi: 10.3390/ijms20112746. Review.

16.

Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis.

Reon BJ, Anaya J, Zhang Y, Mandell J, Purow B, Abounader R, Dutta A.

PLoS Med. 2016 Dec 6;13(12):e1002192. doi: 10.1371/journal.pmed.1002192. eCollection 2016 Dec.

17.

Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.

Duarte CW, Willey CD, Zhi D, Cui X, Harris JJ, Vaughan LK, Mehta T, McCubrey RO, Khodarev NN, Weichselbaum RR, Gillespie GY.

PLoS One. 2012;7(1):e29653. doi: 10.1371/journal.pone.0029653. Epub 2012 Jan 5.

18.

Detection of proneural/mesenchymal marker expression in glioblastoma: temporospatial dynamics and association with chromatin-modifying gene expression.

Murata H, Yoshimoto K, Hatae R, Akagi Y, Mizoguchi M, Hata N, Kuga D, Nakamizo A, Amano T, Sayama T, Iihara K.

J Neurooncol. 2015 Oct;125(1):33-41. doi: 10.1007/s11060-015-1886-y. Epub 2015 Aug 14.

PMID:
26272600
19.

MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma.

Bell JB, Eckerdt FD, Alley K, Magnusson LP, Hussain H, Bi Y, Arslan AD, Clymer J, Alvarez AA, Goldman S, Cheng SY, Nakano I, Horbinski C, Davuluri RV, James CD, Platanias LC.

Mol Cancer Res. 2016 Oct;14(10):984-993. Epub 2016 Jun 30.

20.

Extracellular vesicles in the biology of brain tumour stem cells--Implications for inter-cellular communication, therapy and biomarker development.

Nakano I, Garnier D, Minata M, Rak J.

Semin Cell Dev Biol. 2015 Apr;40:17-26. doi: 10.1016/j.semcdb.2015.02.011. Epub 2015 Feb 23. Review.

PMID:
25721810

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