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Items: 1 to 20 of 98

1.

Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome-mediated metabolic syndrome.

Mosquera MJ, Kim S, Zhou H, Jing TT, Luna M, Guss JD, Reddy P, Lai K, Leifer CA, Brito IL, Hernandez CJ, Singh A.

Sci Adv. 2019 Mar 27;5(3):eaav9788. doi: 10.1126/sciadv.aav9788. eCollection 2019 Mar.

2.

Polyanhydride Nanovaccines Induce Germinal Center B Cell Formation and Sustained Serum Antibody Responses.

Vela Ramirez JE, Tygrett LT, Hao J, Habte HH, Cho MW, Greenspan NS, Waldschmidt TJ, Narasimhan B.

J Biomed Nanotechnol. 2016 Jun;12(6):1303-11.

3.

Deletion of the Toll-Like Receptor 5 Gene Per Se Does Not Determine the Gut Microbiome Profile That Induces Metabolic Syndrome: Environment Trumps Genotype.

Zhang W, Hartmann R, Tun HM, Elson CO, Khafipour E, Garvey WT.

PLoS One. 2016 Mar 7;11(3):e0150943. doi: 10.1371/journal.pone.0150943. eCollection 2016.

4.

Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques.

Kasturi SP, Kozlowski PA, Nakaya HI, Burger MC, Russo P, Pham M, Kovalenkov Y, Silveira ELV, Havenar-Daughton C, Burton SL, Kilgore KM, Johnson MJ, Nabi R, Legere T, Sher ZJ, Chen X, Amara RR, Hunter E, Bosinger SE, Spearman P, Crotty S, Villinger F, Derdeyn CA, Wrammert J, Pulendran B.

J Virol. 2017 Jan 31;91(4). pii: e01844-16. doi: 10.1128/JVI.01844-16. Print 2017 Feb 15.

5.

Nanomaterial-dependent immunoregulation of dendritic cells and its effects on biological activities of contraceptive nanovaccines.

Xu P, Tang S, Jiang L, Yang L, Zhang D, Feng S, Zhao T, Dong Y, He W, Wang R, Zhang J, Liang Z.

J Control Release. 2016 Mar 10;225:252-68. doi: 10.1016/j.jconrel.2016.01.043. Epub 2016 Jan 27.

PMID:
26826303
6.

Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine.

Agallou M, Margaroni M, Athanasiou E, Toubanaki DK, Kontonikola K, Karidi K, Kammona O, Kiparissides C, Karagouni E.

PLoS Negl Trop Dis. 2017 Jan 23;11(1):e0005311. doi: 10.1371/journal.pntd.0005311. eCollection 2017 Jan.

7.

Interaction between gut microbiota and toll-like receptor: from immunity to metabolism.

Yiu JH, Dorweiler B, Woo CW.

J Mol Med (Berl). 2017 Jan;95(1):13-20. doi: 10.1007/s00109-016-1474-4. Epub 2016 Sep 17. Review.

8.

Co-delivery of Dual Toll-Like Receptor Agonists and Antigen in Poly(Lactic-Co-Glycolic) Acid/Polyethylenimine Cationic Hybrid Nanoparticles Promote Efficient In Vivo Immune Responses.

Ebrahimian M, Hashemi M, Maleki M, Hashemitabar G, Abnous K, Ramezani M, Haghparast A.

Front Immunol. 2017 Sep 13;8:1077. doi: 10.3389/fimmu.2017.01077. eCollection 2017.

9.

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation.

Porras D, Nistal E, Martínez-Flórez S, Pisonero-Vaquero S, Olcoz JL, Jover R, González-Gallego J, García-Mediavilla MV, Sánchez-Campos S.

Free Radic Biol Med. 2017 Jan;102:188-202. doi: 10.1016/j.freeradbiomed.2016.11.037. Epub 2016 Nov 25.

PMID:
27890642
10.

Delivery of an inactivated avian influenza virus vaccine adjuvanted with poly(D,L-lactic-co-glycolic acid) encapsulated CpG ODN induces protective immune responses in chickens.

Singh SM, Alkie TN, Nagy É, Kulkarni RR, Hodgins DC, Sharif S.

Vaccine. 2016 Sep 14;34(40):4807-13. doi: 10.1016/j.vaccine.2016.08.009. Epub 2016 Aug 16.

PMID:
27543454
11.

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.

Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT.

Science. 2010 Apr 9;328(5975):228-31. doi: 10.1126/science.1179721. Epub 2010 Mar 4.

12.

The microbiome and regulation of mucosal immunity.

McDermott AJ, Huffnagle GB.

Immunology. 2014 May;142(1):24-31. doi: 10.1111/imm.12231. Review.

13.

Mice harboring pathobiont-free microbiota do not develop intestinal inflammation that normally results from an innate immune deficiency.

Chassaing B, Gewirtz AT.

PLoS One. 2018 Apr 4;13(4):e0195310. doi: 10.1371/journal.pone.0195310. eCollection 2018.

14.

Toll-like receptors in the pathogenesis of chemotherapy-induced gastrointestinal toxicity.

Cario E.

Curr Opin Support Palliat Care. 2016 Jun;10(2):157-64. doi: 10.1097/SPC.0000000000000202. Review.

PMID:
26986508
15.

Latent, Immunosuppressive Nature of Poly(lactic-co-glycolic acid) Microparticles.

Allen RP, Bolandparvaz A, Ma JA, Manickam VA, Lewis JS.

ACS Biomater Sci Eng. 2018 Mar 12;4(3):900-918. doi: 10.1021/acsbiomaterials.7b00831. Epub 2018 Feb 3.

16.

Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome's potential to cause inflammation.

Leifer CA, McConkey C, Li S, Chassaing B, Gewirtz AT, Ley RE.

Immunol Lett. 2014 Dec;162(2 Pt A):3-9. doi: 10.1016/j.imlet.2014.07.017. Epub 2014 Oct 2. Review.

17.

Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice.

Chassaing B, Ley RE, Gewirtz AT.

Gastroenterology. 2014 Dec;147(6):1363-77.e17. doi: 10.1053/j.gastro.2014.08.033. Epub 2014 Aug 27.

18.

Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice.

Kellermayer R, Dowd SE, Harris RA, Balasa A, Schaible TD, Wolcott RD, Tatevian N, Szigeti R, Li Z, Versalovic J, Smith CW.

FASEB J. 2011 May;25(5):1449-60. doi: 10.1096/fj.10-172205. Epub 2011 Jan 12.

19.

Hollow microneedle-mediated intradermal delivery of model vaccine antigen-loaded PLGA nanoparticles elicits protective T cell-mediated immunity to an intracellular bacterium.

de Groot AM, Du G, Mönkäre J, Platteel ACM, Broere F, Bouwstra JA, Sijts AJAM.

J Control Release. 2017 Nov 28;266:27-35. doi: 10.1016/j.jconrel.2017.09.017. Epub 2017 Sep 14.

20.

Obesity, metabolic syndrome, and microbiota: multiple interactions.

Tilg H.

J Clin Gastroenterol. 2010 Sep;44 Suppl 1:S16-8. doi: 10.1097/MCG.0b013e3181dd8b64.

PMID:
20535027

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