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Items: 1 to 20 of 89

1.

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade.

Dantoft W, Robertson KA, Watkins WJ, Strobl B, Ghazal P.

Front Microbiol. 2019 Mar 4;10:355. doi: 10.3389/fmicb.2019.00355. eCollection 2019.

2.

An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.

Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S, Martin K, Griffiths SJ, Enright AJ, Yamamoto M, Pradeepa MM, Lennox KA, Behlke MA, Talbot S, Haas J, Dölken L, Griffiths WJ, Wang Y, Angulo A, Ghazal P.

PLoS Biol. 2016 Mar 3;14(3):e1002364. doi: 10.1371/journal.pbio.1002364. eCollection 2016 Mar.

3.

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.

Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, Osborne T, Wenk MR, Angulo A, Ghazal P.

PLoS Biol. 2011 Mar;9(3):e1000598. doi: 10.1371/journal.pbio.1000598. Epub 2011 Mar 8.

4.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

5.

Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis.

Lu H, Talbot S, Robertson KA, Watterson S, Forster T, Roy D, Ghazal P.

Steroids. 2015 Jul;99(Pt B):219-29. doi: 10.1016/j.steroids.2015.02.022. Epub 2015 Mar 7.

6.

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P.

Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27.

7.

RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production.

Xu L, Wang W, Li Y, Zhou X, Yin Y, Wang Y, de Man RA, van der Laan LJW, Huang F, Kamar N, Peppelenbosch MP, Pan Q.

Hepatology. 2017 Jun;65(6):1823-1839. doi: 10.1002/hep.29105. Epub 2017 May 3.

PMID:
28195391
8.

Yin Yang 1 Dynamically Regulates Antiviral Innate Immune Responses During Viral Infection.

Zan J, Zhang H, Gu AP, Zhong KL, Lu MY, Bai XX, Zhang JY, Cai J.

Cell Physiol Biochem. 2017;44(2):607-617. doi: 10.1159/000485116. Epub 2017 Nov 20.

9.

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.

Sociali G, Grozio A, Caffa I, Schuster S, Becherini P, Damonte P, Sturla L, Fresia C, Passalacqua M, Mazzola F, Raffaelli N, Garten A, Kiess W, Cea M, Nencioni A, Bruzzone S.

FASEB J. 2019 Mar;33(3):3704-3717. doi: 10.1096/fj.201800321R. Epub 2018 Dec 4.

PMID:
30514106
10.

Nipah and Hendra Virus Nucleoproteins Inhibit Nuclear Accumulation of Signal Transducer and Activator of Transcription 1 (STAT1) and STAT2 by Interfering with Their Complex Formation.

Sugai A, Sato H, Takayama I, Yoneda M, Kai C.

J Virol. 2017 Oct 13;91(21). pii: e01136-17. doi: 10.1128/JVI.01136-17. Print 2017 Nov 1.

11.

EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway.

Zhu C, Xiao F, Hong J, Wang K, Liu X, Cai D, Fusco DN, Zhao L, Jeong SW, Brisac C, Chusri P, Schaefer EA, Zhao H, Peng LF, Lin W, Chung RT.

J Virol. 2015 Jul;89(13):6608-18. doi: 10.1128/JVI.00364-15. Epub 2015 Apr 15.

12.

Inhibition of STAT Pathway Impairs Anti-Hepatitis C Virus Effect of Interferon Alpha.

Zhao LJ, He SF, Liu Y, Zhao P, Bian ZQ, Qi ZT.

Cell Physiol Biochem. 2016;40(1-2):77-90. Epub 2016 Nov 18.

13.

Murine gammaherpesvirus 68 encoding open reading frame 11 targets TANK binding kinase 1 to negatively regulate the host type I interferon response.

Kang HR, Cheong WC, Park JE, Ryu S, Cho HJ, Youn H, Ahn JH, Song MJ.

J Virol. 2014 Jun;88(12):6832-46. doi: 10.1128/JVI.03460-13. Epub 2014 Apr 2.

14.

Interferon Control of the Sterol Metabolic Network: Bidirectional Molecular Circuitry-Mediating Host Protection.

Robertson KA, Ghazal P.

Front Immunol. 2016 Dec 23;7:634. doi: 10.3389/fimmu.2016.00634. eCollection 2016. Review.

15.

JAK-STAT signaling pathways are activated in the brain following reovirus infection.

Goody RJ, Beckham JD, Rubtsova K, Tyler KL.

J Neurovirol. 2007 Aug;13(4):373-83.

16.

Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.

Mann BA, Huang JH, Li P, Chang HC, Slee RB, O'Sullivan A, Anita M, Yeh N, Klemsz MJ, Brutkiewicz RR, Blum JS, Kaplan MH.

J Interferon Cytokine Res. 2008 Jun;28(6):367-80. doi: 10.1089/jir.2007.0113.

17.

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein.

Feng L, Sheng J, Vu GP, Liu Y, Foo C, Wu S, Trang P, Paliza-Carre M, Ran Y, Yang X, Sun X, Deng Z, Zhou T, Lu S, Li H, Liu F.

PLoS Pathog. 2018 Jan 29;14(1):e1006867. doi: 10.1371/journal.ppat.1006867. eCollection 2018 Jan.

18.

IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-κB pathway.

Brisac C, Salloum S, Yang V, Schaefer EA, Holmes JA, Chevaliez S, Hong J, Carlton-Smith C, Alatrakchi N, Kruger A, Lin W, Chung RT.

J Hepatol. 2016 Nov;65(5):972-979. doi: 10.1016/j.jhep.2016.06.028. Epub 2016 Jul 9.

19.
20.

Herpes Simplex Virus 1 Serine Protease VP24 Blocks the DNA-Sensing Signal Pathway by Abrogating Activation of Interferon Regulatory Factor 3.

Zhang D, Su C, Zheng C.

J Virol. 2016 May 27;90(12):5824-5829. doi: 10.1128/JVI.00186-16. Print 2016 Jun 15.

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