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Items: 1 to 20 of 99

1.

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.

Chakraborty AA, Laukka T, Myllykoski M, Ringel AE, Booker MA, Tolstorukov MY, Meng YJ, Meier SR, Jennings RB, Creech AL, Herbert ZT, McBrayer SK, Olenchock BA, Jaffe JD, Haigis MC, Beroukhim R, Signoretti S, Koivunen P, Kaelin WG Jr.

Science. 2019 Mar 15;363(6432):1217-1222. doi: 10.1126/science.aaw1026. Epub 2019 Mar 14.

PMID:
30872525
2.
3.

Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases.

Laukka T, Myllykoski M, Looper RE, Koivunen P.

J Mol Biol. 2018 Sep 14;430(18 Pt B):3081-3092. doi: 10.1016/j.jmb.2018.06.048. Epub 2018 Jul 5.

PMID:
29981745
4.

Regulation of histone demethylase KDM6B by hypoxia-inducible factor-2α.

Guo X, Tian Z, Wang X, Pan S, Huang W, Shen Y, Gui Y, Duan X, Cai Z.

Acta Biochim Biophys Sin (Shanghai). 2015 Feb;47(2):106-13. doi: 10.1093/abbs/gmu122. Epub 2014 Dec 17.

PMID:
25520177
5.

UTX demethylase activity is required for satellite cell-mediated muscle regeneration.

Faralli H, Wang C, Nakka K, Benyoucef A, Sebastian S, Zhuang L, Chu A, Palii CG, Liu C, Camellato B, Brand M, Ge K, Dilworth FJ.

J Clin Invest. 2016 Apr 1;126(4):1555-65. doi: 10.1172/JCI83239. Epub 2016 Mar 21.

6.

Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3.

Prickaerts P, Adriaens ME, Beucken TVD, Koch E, Dubois L, Dahlmans VEH, Gits C, Evelo CTA, Chan-Seng-Yue M, Wouters BG, Voncken JW.

Epigenetics Chromatin. 2016 Oct 26;9:46. doi: 10.1186/s13072-016-0086-0. eCollection 2016.

7.

Hypoxia induces rapid changes to histone methylation and reprograms chromatin.

Batie M, Frost J, Frost M, Wilson JW, Schofield P, Rocha S.

Science. 2019 Mar 15;363(6432):1222-1226. doi: 10.1126/science.aau5870. Epub 2019 Mar 14.

PMID:
30872526
8.

Epigenetic regulation by histone demethylases in hypoxia.

Hancock RL, Dunne K, Walport LJ, Flashman E, Kawamura A.

Epigenomics. 2015 Aug;7(5):791-811. doi: 10.2217/epi.15.24. Epub 2015 Apr 2. Review.

9.

JmjC histone demethylases act as chromatin oxygen sensors.

Batie M, Rocha S.

Mol Cell Oncol. 2019 May 7;6(4):1608501. doi: 10.1080/23723556.2019.1608501. eCollection 2019.

PMID:
31211238
10.

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.

Wang AH, Zare H, Mousavi K, Wang C, Moravec CE, Sirotkin HI, Ge K, Gutierrez-Cruz G, Sartorelli V.

EMBO J. 2013 Apr 17;32(8):1075-86. doi: 10.1038/emboj.2013.54. Epub 2013 Mar 15.

11.

Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis.

Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4260-5. doi: 10.1073/pnas.0810067106. Epub 2009 Mar 2.

12.

Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase.

Walport LJ, Hopkinson RJ, Vollmar M, Madden SK, Gileadi C, Oppermann U, Schofield CJ, Johansson C.

J Biol Chem. 2014 Jun 27;289(26):18302-13. doi: 10.1074/jbc.M114.555052. Epub 2014 May 5.

14.

KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development.

Shpargel KB, Starmer J, Yee D, Pohlers M, Magnuson T.

PLoS Genet. 2014 Aug 7;10(8):e1004507. doi: 10.1371/journal.pgen.1004507. eCollection 2014 Aug.

15.

The involvement of histone methylation in osteoblastic differentiation of human periosteum-derived cells cultured in vitro under hypoxic conditions.

Yoon DK, Park JS, Rho GJ, Lee HJ, Sung IY, Son JH, Park BW, Kang YH, Byun SH, Hwang SC, Woo DK, Cho YC, Byun JH.

Cell Biochem Funct. 2017 Oct;35(7):441-452. doi: 10.1002/cbf.3302.

PMID:
29082591
16.

Epigenetic regulation of epithelial-mesenchymal transition by KDM6A histone demethylase in lung cancer cells.

Terashima M, Ishimura A, Wanna-Udom S, Suzuki T.

Biochem Biophys Res Commun. 2017 Sep 2;490(4):1407-1413. doi: 10.1016/j.bbrc.2017.07.048. Epub 2017 Jul 8.

PMID:
28698146
17.

Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases.

Salminen A, Kaarniranta K, Kauppinen A.

Aging Dis. 2016 Mar 15;7(2):180-200. doi: 10.14336/AD.2015.0929. eCollection 2016 Mar. Review.

18.

Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.

Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18439-44. Epub 2007 Nov 14.

19.

Histone demethylase UTX counteracts glucocorticoid deregulation of osteogenesis by modulating histone-dependent and -independent pathways.

Wang FS, Lian WS, Lee MS, Weng WT, Huang YH, Chen YS, Sun YC, Wu SL, Chuang PC, Ko JY.

J Mol Med (Berl). 2017 May;95(5):499-512. doi: 10.1007/s00109-017-1512-x. Epub 2017 Jan 27.

PMID:
28130569
20.

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