Similar articles for PMID: 30849276

Year	Number of Results
1999	1
2000	1
2001	2
2002	1
2003	3
2004	5
2005	5
2006	7
2007	6
2008	4
2009	3
2010	4
2011	5
2012	5
2013	11
2014	6
2015	8
2016	6
2017	9
2018	8
2019	5
2020	6
2021	2
2024	0

1

Inhibition of Cdc42-intersectin interaction by small molecule ZCL367 impedes cancer cell cycle progression, proliferation, migration, and tumor growth.

Aguilar BJ, Zhao Y, Zhou H, Huo S, Chen YH, Lu Q. Aguilar BJ, et al. Cancer Biol Ther. 2019;20(6):740-749. doi: 10.1080/15384047.2018.1564559. Epub 2019 Mar 8. Cancer Biol Ther. 2019. PMID: 30849276 Free PMC article.

2

Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.

Friesland A, Zhao Y, Chen YH, Wang L, Zhou H, Lu Q. Friesland A, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1261-6. doi: 10.1073/pnas.1116051110. Epub 2013 Jan 2. Proc Natl Acad Sci U S A. 2013. PMID: 23284167 Free PMC article.

3

A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.

Zins K, Lucas T, Reichl P, Abraham D, Aharinejad S. Zins K, et al. PLoS One. 2013 Sep 11;8(9):e74924. doi: 10.1371/journal.pone.0074924. eCollection 2013. PLoS One. 2013. PMID: 24040362 Free PMC article.

4

Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.

Zins K, Gunawardhana S, Lucas T, Abraham D, Aharinejad S. Zins K, et al. J Transl Med. 2013 Nov 27;11:295. doi: 10.1186/1479-5876-11-295. J Transl Med. 2013. PMID: 24279335 Free PMC article.

5

A Cdc42 mutant specifically activated by intersectin.

Smith WJ, Hamel B, Yohe ME, Sondek J, Cerione RA, Snyder JT. Smith WJ, et al. Biochemistry. 2005 Oct 11;44(40):13282-90. doi: 10.1021/bi050591b. Biochemistry. 2005. PMID: 16201754

6

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

Hong L, Kenney SR, Phillips GK, Simpson D, Schroeder CE, Nöth J, Romero E, Swanson S, Waller A, Strouse JJ, Carter M, Chigaev A, Ursu O, Oprea T, Hjelle B, Golden JE, Aubé J, Hudson LG, Buranda T, Sklar LA, Wandinger-Ness A. Hong L, et al. J Biol Chem. 2013 Mar 22;288(12):8531-8543. doi: 10.1074/jbc.M112.435941. Epub 2013 Feb 4. J Biol Chem. 2013. PMID: 23382385 Free PMC article.

7

Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras- Related Cancers.

Aguilar BJ, Zhou H, Lu Q. Aguilar BJ, et al. Curr Med Chem. 2017;24(32):3485-3507. doi: 10.2174/0929867324666170602082956. Curr Med Chem. 2017. PMID: 28571533 Review.

8

Maspin controls mammary tumor cell migration through inhibiting Rac1 and Cdc42, but not the RhoA GTPase.

Shi HY, Stafford LJ, Liu Z, Liu M, Zhang M. Shi HY, et al. Cell Motil Cytoskeleton. 2007 May;64(5):338-46. doi: 10.1002/cm.20187. Cell Motil Cytoskeleton. 2007. PMID: 17301947

9

Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.

Wang JB, Wu WJ, Cerione RA. Wang JB, et al. J Biol Chem. 2005 Jun 17;280(24):22883-91. doi: 10.1074/jbc.M414375200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15824104 Free article.

10

Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases.

Zhu Y, Casey PJ, Kumar AP, Pervaiz S. Zhu Y, et al. Cell Death Dis. 2013 Apr 4;4(4):e568. doi: 10.1038/cddis.2013.103. Cell Death Dis. 2013. PMID: 23559002 Free PMC article.

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