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Items: 1 to 20 of 107

1.

A novel STIM1-Orai1 gating interface essential for CRAC channel activation.

Butorac C, Muik M, Derler I, Stadlbauer M, Lunz V, Krizova A, Lindinger S, Schober R, Frischauf I, Bhardwaj R, Hediger MA, Groschner K, Romanin C.

Cell Calcium. 2019 May;79:57-67. doi: 10.1016/j.ceca.2019.02.009. Epub 2019 Feb 23.

2.

Modulation of Orai1 and STIM1 by Cellular Factors.

Woo JS, Srikanth S, Gwack Y.

In: Kozak JA, Putney JW Jr., editors. Calcium Entry Channels in Non-Excitable Cells. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 4.

3.

Store-Independent Orai Channels Regulated by STIM.

Zhang X, Gueguinou M, Trebak M.

In: Kozak JA, Putney JW Jr., editors. Calcium Entry Channels in Non-Excitable Cells. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 11.

4.

Studies of Structure-Function and Subunit Composition of Orai/STIM Channel.

Fahrner M, Schindl R, Romanin C.

In: Kozak JA, Putney JW Jr., editors. Calcium Entry Channels in Non-Excitable Cells. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 2.

5.

Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions.

Cheng KT, Liu X, Ong HL, Swaim W, Ambudkar IS.

PLoS Biol. 2011 Mar;9(3):e1001025. doi: 10.1371/journal.pbio.1001025. Epub 2011 Mar 8.

6.

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1.

Park CY, Hoover PJ, Mullins FM, Bachhawat P, Covington ED, Raunser S, Walz T, Garcia KC, Dolmetsch RE, Lewis RS.

Cell. 2009 Mar 6;136(5):876-90. doi: 10.1016/j.cell.2009.02.014. Epub 2009 Feb 26.

7.

Stoichiometric requirements for trapping and gating of Ca2+ release-activated Ca2+ (CRAC) channels by stromal interaction molecule 1 (STIM1).

Hoover PJ, Lewis RS.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13299-304. doi: 10.1073/pnas.1101664108. Epub 2011 Jul 25.

8.

Voltage gating at the selectivity filter of the Ca2+ release-activated Ca2+ channel induced by mutation of the Orai1 protein.

Spassova MA, Hewavitharana T, Fandino RA, Kaya A, Tanaka J, Gill DL.

J Biol Chem. 2008 May 30;283(22):14938-45. Epub 2007 Dec 20.

9.

The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels.

McNally BA, Somasundaram A, Jairaman A, Yamashita M, Prakriya M.

J Physiol. 2013 Jun 1;591(11):2833-50. doi: 10.1113/jphysiol.2012.250456. Epub 2013 Apr 22.

10.

STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy.

Navarro-Borelly L, Somasundaram A, Yamashita M, Ren D, Miller RJ, Prakriya M.

J Physiol. 2008 Nov 15;586(22):5383-401. doi: 10.1113/jphysiol.2008.162503. Epub 2008 Oct 2.

11.

Optogenetic Approaches to Control Calcium Entry in Non-Excitable Cells.

He L, Zhang Q, Zhou Y, Huang Y.

In: Kozak JA, Putney JW Jr., editors. Calcium Entry Channels in Non-Excitable Cells. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 8.

12.

Critical role for Orai1 C-terminal domain and TM4 in CRAC channel gating.

Palty R, Stanley C, Isacoff EY.

Cell Res. 2015 Aug;25(8):963-80. doi: 10.1038/cr.2015.80. Epub 2015 Jul 3.

13.

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

Fahrner M, Muik M, Schindl R, Butorac C, Stathopulos P, Zheng L, Jardin I, Ikura M, Romanin C.

J Biol Chem. 2014 Nov 28;289(48):33231-44. doi: 10.1074/jbc.M114.610022. Epub 2014 Oct 23.

14.

STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels.

Mullins FM, Park CY, Dolmetsch RE, Lewis RS.

Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15495-500. doi: 10.1073/pnas.0906781106. Epub 2009 Aug 21.

15.

Assessing the Molecular Nature of the STIM1/Orai1 Coupling Interface Using FRET Approaches.

Zhou Y, Wang Y, Gill DL.

In: Kozak JA, Putney JW Jr., editors. Calcium Entry Channels in Non-Excitable Cells. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 7.

16.

Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus.

Derler I, Butorac C, Krizova A, Stadlbauer M, Muik M, Fahrner M, Frischauf I, Romanin C.

J Biol Chem. 2018 Jan 26;293(4):1259-1270. doi: 10.1074/jbc.M117.812206. Epub 2017 Dec 13.

17.

Differential roles of the C and N termini of Orai1 protein in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation.

Zheng H, Zhou MH, Hu C, Kuo E, Peng X, Hu J, Kuo L, Zhang SL.

J Biol Chem. 2013 Apr 19;288(16):11263-72. doi: 10.1074/jbc.M113.450254. Epub 2013 Feb 27.

18.

Complex role of STIM1 in the activation of store-independent Orai1/3 channels.

Zhang X, Zhang W, González-Cobos JC, Jardin I, Romanin C, Matrougui K, Trebak M.

J Gen Physiol. 2014 Mar;143(3):345-59. doi: 10.1085/jgp.201311084.

19.

Intramolecular shielding maintains the ER Ca²⁺ sensor STIM1 in an inactive conformation.

Yu F, Sun L, Hubrack S, Selvaraj S, Machaca K.

J Cell Sci. 2013 Jun 1;126(Pt 11):2401-10. doi: 10.1242/jcs.117200. Epub 2013 Apr 9.

20.

Orai1 and STIM reconstitute store-operated calcium channel function.

Soboloff J, Spassova MA, Tang XD, Hewavitharana T, Xu W, Gill DL.

J Biol Chem. 2006 Jul 28;281(30):20661-5. Epub 2006 Jun 9.

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